Analysis of heparin, alpha-dystroglycan and sulfatide binding to the G domain of the laminin alpha1 chain by site-directed mutagenesis.
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Form and function: the laminin family of heterotrimersStructure of the C-terminal laminin G-like domain pair of the laminin alpha2 chain harbouring binding sites for alpha-dystroglycan and heparinLaminin isoforms containing the gamma3 chain are unable to bind to integrins due to the absence of the glutamic acid residue conserved in the C-terminal regions of the gamma1 and gamma2 chainsDistinct roles for laminin globular domains in laminin alpha1 chain mediated rescue of murine laminin alpha2 chain deficiencyCrystal Structure and Cell Surface Anchorage Sites of Laminin 1LG4-5The Laminin 511/521 binding site on the Lutheran blood group glycoprotein is located at the flexible junction of Ig domains 2 and 3Spatial regulation and activity modulation of plasmin by high affinity binding to the G domain of the alpha 3 subunit of laminin-5Tropoelastin binding to fibulins, nidogen-2 and other extracellular matrix proteinsA unique sequence of the laminin alpha 3 G domain binds to heparin and promotes cell adhesion through syndecan-2 and -4Laminin-121--recombinant expression and interactions with integrinsBinding of laminin-1 to monosialoganglioside GM1 in lipid rafts is crucial for neurite outgrowthLARGE2 generates the same xylose- and glucuronic acid-containing glycan structures as LARGEBeta1 integrin and alpha-dystroglycan binding sites are localized to different laminin-G-domain-like (LG) modules within the laminin alpha5 chain G domain.laminin alpha 1 gene is essential for normal lens development in zebrafish.Laminins: structure and genetic regulation.Proteolytic modification of laminins: functional consequences.Order and disorder: the role of extracellular matrix in epithelial cancer.Glycoproteomic characterization of recombinant mouse α-dystroglycan.Interactions of laminin with the amyloid beta peptide. Implications for Alzheimer's disease.Flow cytometry for the analysis of α-dystroglycan glycosylation in fibroblasts from patients with dystroglycanopathies.HNK-1 glycan functions as a tumor suppressor for astrocytic tumor.Old World and clade C New World arenaviruses mimic the molecular mechanism of receptor recognition used by alpha-dystroglycan's host-derived ligands.Functional sites in the laminin alpha chains.Laminin-sulfatide binding initiates basement membrane assembly and enables receptor signaling in Schwann cells and fibroblastsMatrix assembly, regulation, and survival functions of laminin and its receptors in embryonic stem cell differentiation.Molecular analysis of the interaction of LCMV with its cellular receptor [alpha]-dystroglycan.The rapid decrease in astrocyte-associated dystroglycan expression by focal cerebral ischemia is protease-dependent.Perlecan and Dystroglycan act at the basal side of the Drosophila follicular epithelium to maintain epithelial organization.The myotomal basement membrane: insight into laminin-111 function and its control by Sonic hedgehog signaling.Identification of a major heparin and cell binding site in the LG4 module of the laminin alpha 5 chain.Molecular dissection of the alpha-dystroglycan- and integrin-binding sites within the globular domain of human laminin-10.Cell surface proteoglycans syndecan-1 and -4 bind overlapping but distinct sites in laminin α3 LG45 protein domain.The tumor supressor function of STGC3 and its reduced expression in nasopharyngeal carcinoma.The requirement of the glutamic acid residue at the third position from the carboxyl termini of the laminin gamma chains in integrin binding by laminins.A novel strategy for defining critical amino acid residues involved in protein/glycosaminoglycan interactions.Laminin-6 is activated by proteolytic processing and regulates cellular adhesion and migration differently from laminin-5.Perlecan domain V of Drosophila melanogaster. Sequence, recombinant analysis and tissue expression.Mutation of a basic sequence in the laminin alpha2LG3 module leads to a lack of proteolytic processing and has different effects on beta1 integrin-mediated cell adhesion and alpha-dystroglycan binding.Complete sequence, recombinant analysis and binding to laminins and sulphated ligands of the N-terminal domains of laminin alpha3B and alpha5 chains.Differential expression of perlecan receptors, α-dystroglycan and integrin β1, before and after invasion of oral squamous cell carcinoma.
P2860
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P2860
Analysis of heparin, alpha-dystroglycan and sulfatide binding to the G domain of the laminin alpha1 chain by site-directed mutagenesis.
description
1999 nî lūn-bûn
@nan
1999 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի մարտին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
name
Analysis of heparin, alpha-dys ...... by site-directed mutagenesis.
@ast
Analysis of heparin, alpha-dys ...... by site-directed mutagenesis.
@en
type
label
Analysis of heparin, alpha-dys ...... by site-directed mutagenesis.
@ast
Analysis of heparin, alpha-dys ...... by site-directed mutagenesis.
@en
prefLabel
Analysis of heparin, alpha-dys ...... by site-directed mutagenesis.
@ast
Analysis of heparin, alpha-dys ...... by site-directed mutagenesis.
@en
P2093
P356
P1476
Analysis of heparin, alpha-dys ...... by site-directed mutagenesis.
@en
P2093
P304
P356
10.1006/JMBI.1999.2606
P407
P577
1999-03-01T00:00:00Z