Design, synthesis, biological activity, and ADME properties of pyrazolo[3,4-d]pyrimidines active in hypoxic human leukemia cells: a lead optimization study.

Design, synthesis, biological activity, and ADME properties of pyrazolo[3,4-d]pyrimidines active in hypoxic human leukemia cells: a lead optimization study.

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http://www.wikidata.org/entity/Q33857013
An update on dual Src/Abl inhibitors.Identification of Hck inhibitors as hits for the development of antileukemia and anti-HIV agents.Opening the door to the development of novel Abl kinase inhibitors.Novel 1,5-diphenyl-6-substituted 1H-pyrazolo[3,4-d]pyrimidin-4(5H)-ones induced apoptosis in RKO colon cancer cells.SRC family kinase inhibition through a new pyrazolo[3,4-d]pyrimidine derivative as a feasible approach for glioblastoma treatment.Probing the binding site of abl tyrosine kinase using in situ click chemistry.Pyrazolo[3,4-d]pyrimidine Prodrugs: Strategic Optimization of the Aqueous Solubility of Dual Src/Abl Inhibitors.Dipyrazolo[1,5-a:4',3'-c]pyridines - a new heterocyclic system accessed via multicomponent reaction.The SGK1 inhibitor SI113 induces autophagy, apoptosis, and endoplasmic reticulum stress in endometrial cancer cells.Water Solubility Enhancement of Pyrazolo[3,4-d]pyrimidine Derivatives via Miniaturized Polymer-Drug Microarrays.Theoretical Studies on Pyrazolo[3,4-d]pyrimidine Derivatives as Potent Dual c-Src/Abl Inhibitors Using 3D-QSAR and Docking Approaches.Synthesis and Tautomerism of Substituted Pyrazolo[4,3-c]pyrazoles
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Design, synthesis, biological activity, and ADME properties of pyrazolo[3,4-d]pyrimidines active in hypoxic human leukemia cells: a lead optimization study.

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http://www.wikidata.org/entity/Q33857013
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2011 թուականի Մարտին հրատարակուած գիտական յօդուած
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2011 թվականի մարտին հրատարակված գիտական հոդված
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2011年の論文
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2011年論文
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2011年論文
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2011年論文
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2011年論文
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2011年論文
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2011年论文
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Design, synthesis, biological ...... ls: a lead optimization study.
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Design, synthesis, biological ...... ls: a lead optimization study.
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Design, synthesis, biological ...... ls: a lead optimization study.
@ast
Design, synthesis, biological ...... ls: a lead optimization study.
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Design, synthesis, biological ...... ls: a lead optimization study.
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Design, synthesis, biological ...... ls: a lead optimization study.
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P1433
P1476
P2093
P304
P31
P356
P407
P433
P478
P50
P577
P698
P921
P356
P1433
P1476
Design, synthesis, biological ...... lls: a lead optimization study
@en
P2093
P304
P31
P356
P407
P433
P478
P50
P577
P698
P921