Theoretical Studies on Pyrazolo[3,4-d]pyrimidine Derivatives as Potent Dual c-Src/Abl Inhibitors Using 3D-QSAR and Docking Approaches.

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Theoretical Studies on Pyrazolo[3,4-d]pyrimidine Derivatives as Potent Dual c-Src/Abl Inhibitors Using 3D-QSAR and Docking Approaches.

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2014 nî lūn-bûn

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2014年の論文

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2014年学术文章

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2014年学术文章

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2014年学术文章

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2014年学术文章

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2014年学术文章

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2014年學術文章

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2014年學術文章

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2014年學術文章

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Theoretical Studies on Pyrazol ...... D-QSAR and Docking Approaches.

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Theoretical Studies on Pyrazol ...... D-QSAR and Docking Approaches.

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Item

label

Theoretical Studies on Pyrazol ...... D-QSAR and Docking Approaches.

@en

Theoretical Studies on Pyrazol ...... D-QSAR and Docking Approaches.

@nl

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Theoretical Studies on Pyrazol ...... D-QSAR and Docking Approaches.

@en

Theoretical Studies on Pyrazol ...... D-QSAR and Docking Approaches.

@nl

P1476

Theoretical Studies on Pyrazol ...... D-QSAR and Docking Approaches.

@en

P2093

Dan Qing Fang

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Guo Hua Zeng

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Jing Heng Wu

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Ju Ping Wang

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Shao Jie Ma

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Wen Guo Xie

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Wen Juan Wu

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Yong Shen

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P2860

Newest findings on the oldest oncogene; how activated src does it

Protein structure alignment by incremental combinatorial extension (CE) of the optimal path

Letter: A new consistent chromosomal abnormality in chronic myelogenous leukaemia identified by quinacrine fluorescence and Giemsa staining

Overriding imatinib resistance with a novel ABL kinase inhibitor

Src family kinases, key regulators of signal transduction.

Development of CoMFA and CoMSIA models of cytotoxicity data of anti-HIV-1-phenylamino-1H-imidazole derivatives.

Determination of permeability and lipophilicity of pyrazolo-pyrimidine tyrosine kinase inhibitors and correlation with biological data.

Design, synthesis, biological activity, and ADME properties of pyrazolo[3,4-d]pyrimidines active in hypoxic human leukemia cells: a lead optimization study.

An update on dual Src/Abl inhibitors.

N-(5-chloro-1,3-benzodioxol-4-yl)-7-[2-(4-methylpiperazin-1-yl)ethoxy]-5- (tetrahydro-2H-pyran-4-yloxy)quinazolin-4-amine, a novel, highly selective, orally available, dual-specific c-Src/Abl kinase inhibitor.

P304

183-200

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P31

scholarly article

P356

10.1002/MINF.201300126

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P433

http://www.w3.org/2001/XMLSchema#string

P478

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P577

2014-03-11T00:00:00Z

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P698

27485688

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