Development of a selective modulator of aryl hydrocarbon (Ah) receptor activity that exhibits anti-inflammatory properties.
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Influence of light on aryl hydrocarbon receptor signaling and consequences in drug metabolism, physiology and diseaseExactly the same but different: promiscuity and diversity in the molecular mechanisms of action of the aryl hydrocarbon (dioxin) receptorComparisons of differential gene expression elicited by TCDD, PCB126, βNF, or ICZ in mouse hepatoma Hepa1c1c7 cells and C57BL/6 mouse liver.Distinct roles for aryl hydrocarbon receptor nuclear translocator and ah receptor in estrogen-mediated signaling in human cancer cell lines.The aryl hydrocarbon receptor ligand omeprazole inhibits breast cancer cell invasion and metastasisAh receptor antagonism inhibits constitutive and cytokine inducible IL6 production in head and neck tumor cell lines.Xenobiotic metabolism, disposition, and regulation by receptors: from biochemical phenomenon to predictors of major toxicitiesChemoprevention of chemically induced skin tumorigenesis by ligand activation of peroxisome proliferator-activated receptor-beta/delta and inhibition of cyclooxygenase 2.Suppression of cytokine-mediated complement factor gene expression through selective activation of the Ah receptor with 3',4'-dimethoxy-α-naphthoflavoneAryl hydrocarbon receptor-dependent retention of nuclear HuR suppresses cigarette smoke-induced cyclooxygenase-2 expression independent of DNA-binding.Identification of a high-affinity ligand that exhibits complete aryl hydrocarbon receptor antagonism.Aryl hydrocarbon receptor ligands in cancer: friend and foe.Genetic and pharmacological analysis identifies a physiological role for the AHR in epidermal differentiation.Aryl hydrocarbon receptor agonists induce microRNA-335 expression and inhibit lung metastasis of estrogen receptor negative breast cancer cells.Differential regulation of Th17 and T regulatory cell differentiation by aryl hydrocarbon receptor dependent xenobiotic response element dependent and independent pathwaysAryl hydrocarbon receptor regulates the cholesterol biosynthetic pathway in a dioxin response element-independent mannerIndole and Tryptophan Metabolism: Endogenous and Dietary Routes to Ah Receptor Activation.Selective aryl hydrocarbon receptor modulator-mediated repression of CD55 expression induced by cytokine exposureAryl Hydrocarbon Receptor Activation Synergistically Induces Lipopolysaccharide-Mediated Expression of Proinflammatory Chemokine (c-c motif) Ligand 20.Lack of ligand-selective binding of the aryl hydrocarbon receptor to putative DNA binding sites regulating expression of Bax and paraoxonase 1 genes.Ligand promiscuity of aryl hydrocarbon receptor agonists and antagonists revealed by site-directed mutagenesis.Ah receptor antagonism represses head and neck tumor cell aggressive phenotype.A role of the aryl hydrocarbon receptor in attenuation of colitis.Atranorin and lecanoric acid antagonize TCDD-induced xenobiotic response element-driven activity, but not xenobiotic response element-independent activity.Editor's Highlight: Ah Receptor Activation Potentiates Neutrophil Chemoattractant (C-X-C Motif) Ligand 5 Expression in Keratinocytes and Skin.High AHR expression in breast tumors correlates with expression of genes from several signaling pathways namely inflammation and endogenous tryptophan metabolism.Targeting STUB1-tissue factor axis normalizes hyperthrombotic uremic phenotype without increasing bleeding risk.Ligand-mediated cytoplasmic retention of the Ah receptor inhibits macrophage-mediated acute inflammatory responses.Synthesis of 1H-indazoles from N-tosylhydrazones and nitroaromatic compounds.
P2860
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P2860
Development of a selective modulator of aryl hydrocarbon (Ah) receptor activity that exhibits anti-inflammatory properties.
description
2010 nî lūn-bûn
@nan
2010 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Development of a selective mod ...... anti-inflammatory properties.
@ast
Development of a selective mod ...... anti-inflammatory properties.
@en
type
label
Development of a selective mod ...... anti-inflammatory properties.
@ast
Development of a selective mod ...... anti-inflammatory properties.
@en
prefLabel
Development of a selective mod ...... anti-inflammatory properties.
@ast
Development of a selective mod ...... anti-inflammatory properties.
@en
P2093
P2860
P356
P1476
Development of a selective mod ...... anti-inflammatory properties.
@en
P2093
Arun K Sharma
Brett C DiNatale
Chris Chiaro
Colin Flaveny
Gary H Perdew
Gowdahalli Krishnegowda
Iain A Murray
Jyh-Ming Lin
Shantu Amin
P2860
P304
P356
10.1021/TX100045H
P577
2010-05-01T00:00:00Z