What can the structures of enzyme-inhibitor complexes tell us about the structures of enzyme substrate complexes?
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Human mesotrypsin is a unique digestive protease specialized for the degradation of trypsin inhibitorsCrystal structures of the FXIa catalytic domain in complex with ecotin mutants reveal substrate-like interactionsEvolutionary families of peptidase inhibitorsComplexation of two proteic insect inhibitors to the active site of chymotrypsin suggests decoupled roles for binding and selectivityComparative structure analysis of proteinase inhibitors from the desert locust, Schistocerca gregariaA clogged gutter mechanism for protease inhibitors.The (1)H-NMR solution structure of the antitryptic core peptide of Bowman-Birk inhibitor proteins: a minimal canonical loopEnzymatic cyclization of a potent bowman-birk protease inhibitor, sunflower trypsin inhibitor-1, and solution structure of an acyclic precursor peptideRigidification of a Flexible Protease Inhibitor Variant upon Binding to TrypsinStructural basis of inhibition revealed by a 1:2 complex of the two-headed tomato inhibitor-II and subtilisin CarlsbergUnbound form of tomato inhibitor-II reveals interdomain flexibility and conformational variability in the reactive site loopsFunctional and Structural Roles of the Cys14–Cys38 Disulfide of Bovine Pancreatic Trypsin InhibitorDeterminants of Affinity and Proteolytic Stability in Interactions of Kunitz Family Protease Inhibitors with MesotrypsinRegulation of an intracellular subtilisin protease activity by a short propeptide sequence through an original combined dual mechanismStructural evidence for standard-mechanism inhibition in metallopeptidases from a complex poised to resynthesize a peptide bondStructural Basis of Trypsin Inhibition and Entomotoxicity of Cospin, Serine Protease Inhibitor Involved in Defense of Coprinopsis cinerea Fruiting BodiesPresence versus absence of hydrogen bond donor Tyr-39 influences interactions of cationic trypsin and mesotrypsin with protein protease inhibitorsComparison of complexes formed by a crustacean and a vertebrate trypsin with bovine pancreatic trypsin inhibitor - the key to achieving extreme stability?Atomic resolution crystal structure of HV-BBI protease inhibitor from amphibian skin in complex with bovine trypsinPlant Protease Inhibitors in Therapeutics-Focus on Cancer TherapyMastering the canonical loop of serine protease inhibitors: enhancing potency by optimising the internal hydrogen bond networkThe trypsin inhibitor panulirin regulates the prophenoloxidase-activating system in the spiny lobster Panulirus argus.Substrate turnover and inhibitor binding as selection parameters in directed evolution of blood coagulation factor Xa.Crystallization, data collection and processing of the chymotrypsin-BTCI-trypsin ternary complexFrog albumin is expressed in skin and characterized as a novel potent trypsin inhibitorSunflower trypsin inhibitor-1, proteolytic studies on a trypsin inhibitor peptide and its analogs.Strengths and weaknesses of data-driven docking in critical assessment of prediction of interactions.Serine Protease Inhibitors in Ticks: An Overview of Their Role in Tick Biology and Tick-Borne Pathogen Transmission.Analysis of binding properties and specificity through identification of the interface forming residues (IFR) for serine proteases in silico docked to different inhibitorsA flow cytometry-based screening system for directed evolution of proteases.Predicting the reactivity of proteins from their sequence alone: Kazal family of protein inhibitors of serine proteinases.pH dependence thermal stability of a chymotrypsin inhibitor from Schizolobium parahyba seeds.The mammary gland-specific marsupial ELP and eutherian CTI share a common ancestral gene.The molecular structure and catalytic mechanism of a novel carboxyl peptidase from Scytalidium lignicolum.Phage selection of cyclic peptide antagonists with increased stability toward intestinal proteases.Bacterial protease inhibitors.Purification, crystallization and X-ray characterization of a Kunitz-type trypsin inhibitor protein from the seeds of chickpea (Cicer arietinum).Primary Structure of a Trypsin Inhibitor (Copaifera langsdorffii Trypsin Inhibitor-1) Obtained from C. langsdorffii SeedsThe many faces of protease-protein inhibitor interactionHuman mesotrypsin defies natural trypsin inhibitors: from passive resistance to active destruction.
P2860
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P2860
What can the structures of enzyme-inhibitor complexes tell us about the structures of enzyme substrate complexes?
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2000 nî lūn-bûn
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2000 թուականի Մարտին հրատարակուած գիտական յօդուած
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2000年の論文
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2000年論文
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2000年論文
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2000年論文
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name
What can the structures of enz ...... of enzyme substrate complexes?
@ast
What can the structures of enz ...... of enzyme substrate complexes?
@en
type
label
What can the structures of enz ...... of enzyme substrate complexes?
@ast
What can the structures of enz ...... of enzyme substrate complexes?
@en
prefLabel
What can the structures of enz ...... of enzyme substrate complexes?
@ast
What can the structures of enz ...... of enzyme substrate complexes?
@en
P1476
What can the structures of enz ...... of enzyme substrate complexes?
@en
P2093
M Laskowski
P304
P356
10.1016/S0167-4838(99)00284-8
P407
P577
2000-03-01T00:00:00Z