Small molecule inhibitor of the RPA70 N-terminal protein interaction domain discovered using in silico and in vitro methods.
about
DNA repair targeted therapy: The past or future of cancer treatment?Discovery of Protein–Protein Interaction Inhibitors of Replication Protein ASurface Reengineering of RPA70N Enables Cocrystallization with an Inhibitor of the Replication Protein A Interaction Motif of ATR Interacting ProteinDiscovery of a Potent Inhibitor of Replication Protein A Protein–Protein Interactions Using a Fragment-Linking ApproachDiscovery of a Potent Stapled Helix Peptide That Binds to the 70N Domain of Replication Protein AA high-throughput fluorescence polarization anisotropy assay for the 70N domain of replication protein A.RPA inhibition increases replication stress and suppresses tumor growth.A small molecule directly inhibits the p53 transactivation domain from binding to replication protein A.Characterization of the interaction between Rfa1 and Rad24 in Saccharomyces cerevisiaeState-of-the-art strategies for targeting protein-protein interactions by small-molecule inhibitors.Identification and Optimization of Anthranilic Acid Based Inhibitors of Replication Protein AIdentification of small molecule inhibitors of ERCC1-XPF that inhibit DNA repair and potentiate cisplatin efficacy in cancer cells.Targeting homologous recombination-mediated DNA repair in cancer.TIPIN depletion leads to apoptosis in breast cancer cells.Targeting repair pathways with small molecules increases precise genome editing in pluripotent stem cells.
P2860
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P2860
Small molecule inhibitor of the RPA70 N-terminal protein interaction domain discovered using in silico and in vitro methods.
description
2011 nî lūn-bûn
@nan
2011 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի մարտին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Small molecule inhibitor of th ...... n silico and in vitro methods.
@ast
Small molecule inhibitor of th ...... n silico and in vitro methods.
@en
type
label
Small molecule inhibitor of th ...... n silico and in vitro methods.
@ast
Small molecule inhibitor of th ...... n silico and in vitro methods.
@en
prefLabel
Small molecule inhibitor of th ...... n silico and in vitro methods.
@ast
Small molecule inhibitor of th ...... n silico and in vitro methods.
@en
P2860
P1476
Small molecule inhibitor of th ...... n silico and in vitro methods.
@en
P2093
Jason G Glanzer
Shengqin Liu
P2860
P304
P356
10.1016/J.BMC.2011.03.012
P407
P577
2011-03-12T00:00:00Z