Identification of small molecule inhibitors of ERCC1-XPF that inhibit DNA repair and potentiate cisplatin efficacy in cancer cells.
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Drugging the Cancers Addicted to DNA Repair.Targeting DNA repair and replication stress in the treatment of ovarian cancer.Disruption of DNA repair in cancer cells by ubiquitination of a destabilising dimerization domain of nucleotide excision repair protein ERCC1.PFKFB3 blockade inhibits hepatocellular carcinoma growth by impairing DNA repair through AKT.Computational Characterization of Small Molecules Binding to the Human XPF Active Site and Virtual Screening to Identify Potential New DNA Repair Inhibitors Targeting the ERCC1-XPF Endonuclease.
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Identification of small molecule inhibitors of ERCC1-XPF that inhibit DNA repair and potentiate cisplatin efficacy in cancer cells.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 16 September 2016
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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Identification of small molecu ...... atin efficacy in cancer cells.
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Identification of small molecu ...... atin efficacy in cancer cells.
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type
label
Identification of small molecu ...... atin efficacy in cancer cells.
@en
Identification of small molecu ...... atin efficacy in cancer cells.
@nl
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Identification of small molecu ...... atin efficacy in cancer cells.
@en
Identification of small molecu ...... atin efficacy in cancer cells.
@nl
P2093
P2860
P356
P1433
P1476
Identification of small molecu ...... latin efficacy in cancer cells
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P2093
Ashley M Floyd
Elaine M Chalfin
Gerold Bepler
Kristin Tillison
Sanjeevani Arora
Steve M Patrick
Vivian Kalman-Maltese
P2860
P304
75104-75117
P356
10.18632/ONCOTARGET.12072
P407
P50
P577
2016-11-01T00:00:00Z