Cell cycle regulation of Dfp1, an activator of the Hsk1 protein kinase.
about
Transcriptional co-activator LEDGF interacts with Cdc7-activator of S-phase kinase (ASK) and stimulates its enzymatic activityCdc7-Dbf4 and the human S checkpoint response to UVCA Xenopus Dbf4 homolog is required for Cdc7 chromatin binding and DNA replicationGenomic instability in cancer.Human Cdc7-related kinase complex. In vitro phosphorylation of MCM by concerted actions of Cdks and Cdc7 and that of a criticial threonine residue of Cdc7 bY CdksHierarchy of S-phase-promoting factors: yeast Dbf4-Cdc7 kinase requires prior S-phase cyclin-dependent kinase activation.The C-terminus of S. pombe DDK subunit Dfp1 is required for meiosis-specific transcription and cohesin cleavage.Cell cycle regulation of chromatin binding and nuclear localization of human Cdc7-ASK kinase complex.Checkpoint independence of most DNA replication origins in fission yeastSchizosaccharomyces pombe Swi1, Swi3, and Hsk1 are components of a novel S-phase response pathway to alkylation damage.Fission yeast Hsk1 (Cdc7) kinase is required after replication initiation for induced mutagenesis and proper response to DNA alkylation damage.Identification of cell cycle-regulated genes in fission yeastDNA replication and damage checkpoints and meiotic cell cycle controls in the fission and budding yeasts.Regulation and roles of Cdc7 kinase under replication stress.mcl1+, the Schizosaccharomyces pombe homologue of CTF4, is important for chromosome replication, cohesion, and segregation.The Cdc7/Dbf4 protein kinase: target of the S phase checkpoint?A conserved domain of Schizosaccharomyces pombe dfp1(+) is uniquely required for chromosome stability following alkylation damage during S phaseCdc7 kinase complex: a key regulator in the initiation of DNA replication.The Cdc23 (Mcm10) protein is required for the phosphorylation of minichromosome maintenance complex by the Dfp1-Hsk1 kinase.Eukaryotic MCM proteins: beyond replication initiation.Dbf4 is direct downstream target of ataxia telangiectasia mutated (ATM) and ataxia telangiectasia and Rad3-related (ATR) protein to regulate intra-S-phase checkpoint.Hypomorphic mutation in an essential cell-cycle kinase causes growth retardation and impaired spermatogenesis.Integrating S-phase checkpoint signaling with trans-lesion synthesis of bulky DNA adducts.Roles of CDK and DDK in Genome Duplication and Maintenance: Meiotic Singularities.Cds1 controls the release of Cdc14-like phosphatase Flp1 from the nucleolus to drive full activation of the checkpoint response to replication stress in fission yeast.Regulation of initiation of S phase, replication checkpoint signaling, and maintenance of mitotic chromosome structures during S phase by Hsk1 kinase in the fission yeast.Multiple pathways can bypass the essential role of fission yeast Hsk1 kinase in DNA replication initiation.Schizosaccharomyces pombe Hsk1p is a potential cds1p target required for genome integrity.Interactions between Swi1-Swi3, Mrc1 and S phase kinase, Hsk1 may regulate cellular responses to stalled replication forks in fission yeast.Novel fission yeast Cdc7-Dbf4-like kinase complex required for the initiation and progression of meiotic second division.Identification of stimulators and inhibitors of Cdc7 kinase in vitro.Xenopus cdc7 function is dependent on licensing but not on XORC, XCdc6, or CDK activity and is required for XCdc45 loading.Hsk1- and SCF(Pof3)-dependent proteolysis of S. pombe Ams2 ensures histone homeostasis and centromere function.Premature structural changes at replication origins in a yeast minichromosome maintenance (MCM) mutant.A synthetic human kinase can control cell cycle progression in budding yeast.A mutation in Dbf4 motif M impairs interactions with DNA replication factors and confers increased resistance to genotoxic agents.Characterization of a novel ATR-dependent, Chk1-independent, intra-S-phase checkpoint that suppresses initiation of replication in Xenopus.Bipartite binding of a kinase activator activates Cdc7-related kinase essential for S phase.Xenopus Drf1, a regulator of Cdc7, displays checkpoint-dependent accumulation on chromatin during an S-phase arrest.Schizosaccharomyces pombe Ddb1 is functionally linked to the replication checkpoint pathway.
P2860
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P2860
Cell cycle regulation of Dfp1, an activator of the Hsk1 protein kinase.
description
1999 nî lūn-bûn
@nan
1999 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Cell cycle regulation of Dfp1, an activator of the Hsk1 protein kinase.
@ast
Cell cycle regulation of Dfp1, an activator of the Hsk1 protein kinase.
@en
type
label
Cell cycle regulation of Dfp1, an activator of the Hsk1 protein kinase.
@ast
Cell cycle regulation of Dfp1, an activator of the Hsk1 protein kinase.
@en
prefLabel
Cell cycle regulation of Dfp1, an activator of the Hsk1 protein kinase.
@ast
Cell cycle regulation of Dfp1, an activator of the Hsk1 protein kinase.
@en
P2860
P356
P1476
Cell cycle regulation of Dfp1, an activator of the Hsk1 protein kinase.
@en
P2093
P2860
P304
P356
10.1073/PNAS.96.15.8443
P407
P577
1999-07-01T00:00:00Z