Antibody-targeted superantigens are potent inducers of tumor-infiltrating T lymphocytes in vivo - Wikidata - wikimedia - TriplyDB

Antibody-targeted superantigens are potent inducers of tumor-infiltrating T lymphocytes in vivo

Antibody-targeted superantigens are potent inducers of tumor-infiltrating T lymphocytes in vivo

http://www.wikidata.org/entity/Q33870240

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A3--a novel colon and pancreatic cancer reactive antibody from a primate phage library selected using intact tumour cells.Targeting of hepatoma cell and suppression of tumor growth by a novel 12mer peptide fused to superantigen TSST-1 Solid tumor-targeted infiltrating cytotoxic T lymphocytes retained by a superantigen fusion protein The tumor targeted superantigen ABR-217620 selectively engages TRBV7-9 and exploits TCR-pMHC affinity mimicry in mediating T cell cytotoxicity.Immunological response and overall survival in a subset of advanced renal cell carcinoma patients from a randomized phase 2/3 study of naptumomab estafenatox plus IFN-α versus IFN-α.Tumor therapy with an antibody-targeted superantigen generates a dichotomy between local and systemic immune responses.Genetically engineered superantigens as tolerable antitumor agents.A phase II study of a 5T4 oncofoetal antigen tumour-targeted superantigen (ABR-214936) therapy in patients with advanced renal cell carcinoma.The distinct role of CD4+ and CD8+ T-cells during the anti-tumour effects of targeted superantigens.Therapy of human non-small-cell lung carcinoma using antibody targeting of a modified superantigen.Naptumomab estafenatox: a new immunoconjugate.Naptumomab estafenatox: targeted immunotherapy with a novel immunotoxin PBMC activation via the ERK and STAT signaling pathways enhances the anti-tumor activity of Staphylococcal enterotoxin A.5T4 oncofoetal antigen: an attractive target for immune intervention in cancer.Endothelial cells expressing an inflammatory phenotype are lysed by superantigen-targeted cytotoxic T cells.Polyethylenimine-mediated in vivo gene transfer of a transmembrane superantigen fusion construct inhibits B16 murine melanoma growth.Intratumoral IL-18 gene transfer improves therapeutic efficacy of antibody-targeted superantigen in established murine melanoma.Identification of framework residues in a secreted recombinant antibody fragment that control production level and localization in Escherichia coli.

P2860

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P2860

Antibody-targeted superantigens are potent inducers of tumor-infiltrating T lymphocytes in vivo

http://www.wikidata.org/entity/Q33870240

description

1995 nî lūn-bûn

@nan

1995 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

1995 թվականի հոտեմբերին հրատարակված գիտական հոդված

@hy

1995年の論文

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1995年論文

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1995年論文

@zh-hant

1995年論文

@zh-hk

1995年論文

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1995年論文

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1995年论文

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name

Antibody-targeted superantigen ...... ltrating T lymphocytes in vivo

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Antibody-targeted superantigen ...... ltrating T lymphocytes in vivo

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type

label

Antibody-targeted superantigen ...... ltrating T lymphocytes in vivo

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Antibody-targeted superantigen ...... ltrating T lymphocytes in vivo

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prefLabel

Antibody-targeted superantigen ...... ltrating T lymphocytes in vivo

@ast

Antibody-targeted superantigen ...... ltrating T lymphocytes in vivo

@en

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Proceedings of the National Academy of Sciences of the United States of America

P1476

Antibody-targeted superantigen ...... ltrating T lymphocytes in vivo

@en

P2093

Hansson J

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Kalland T

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Litton M

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Ohlsson L

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P2860

Monoclonal antibody-superantigen fusion proteins: tumor-specific agents for T-cell-based tumor therapy.

Synergistic antitumor activity of tumor-infiltrating lymphocytes, interleukin 2, and local tumor irradiation. Studies on the mechanism of action.

Tumor immunogenicity determines the effect of B7 costimulation on T cell-mediated tumor immunity.

Major histocompatibility complex class II+B7-1+ tumor cells are potent vaccines for stimulating tumor rejection in tumor-bearing mice

Treatment of established lung metastases with tumor-infiltrating lymphocytes derived from a poorly immunogenic tumor engineered to secrete human TNF-alpha

Staphylococcal enterotoxin-dependent cell-mediated cytotoxicity.

Staphylococcal enterotoxin microbial superantigens.

Superantigens: bacterial and viral proteins that manipulate the immune system.

Isolation, partial characterization, and molecular cloning of a human colon adenocarcinoma cell-surface glycoprotein recognized by the C215 mouse monoclonal antibody.

Tumor-selective cytotoxic effects of murine tumor necrosis factor (TNF) and interferon-gamma (IFN-gamma) in organ culture of B16 melanoma cells and heart tissue.

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9791-9795

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scholarly article

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10.1073/PNAS.92.21.9791

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21

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92

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Mikael Dohlsten

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1995-10-01T00:00:00Z

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15631337

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7568219

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40888

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