PTEN C-terminal deletion causes genomic instability and tumor development. - Wikidata - wikimedia - TriplyDB

PTEN C-terminal deletion causes genomic instability and tumor development.

PTEN C-terminal deletion causes genomic instability and tumor development.

http://www.wikidata.org/entity/Q33874805

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The relevance of PTEN-AKT in relation to NOTCH1-directed treatment strategies in T-cell acute lymphoblastic leukemia Posttranslational regulation of phosphatase and tensin homolog (PTEN) and its functional impact on cancer behaviors.PTEN interacts with histone H1 and controls chromatin condensation.PTEN: Multiple Functions in Human Malignant Tumors Mathematical Modelling of Molecular Pathways Enabling Tumour Cell Invasion and Migration.Noncatalytic PTEN missense mutation predisposes to organ-selective cancer development in vivo PTEN loss is associated with follicular variant of Middle Eastern papillary thyroid carcinoma PTEN regulates RPA1 and protects DNA replication forks.PTEN stabilizes TOP2A and regulates the DNA decatenation PTEN regulates EG5 to control spindle architecture and chromosome congression during mitosis.Pten regulates spindle pole movement through Dlg1-mediated recruitment of Eg5 to centrosomes Multi-platform molecular profiling of a large cohort of glioblastomas reveals potential therapeutic strategies.Genome maintenance in the context of 4D chromatin condensation.PTEN regulates DNA replication progression and stalled fork recovery.Nuclear PTEN tumor-suppressor functions through maintaining heterochromatin structure.Combining PARP inhibitors with radiation therapy for the treatment of glioblastoma: Is PTEN predictive of response?PTEN proteoforms in biology and disease.PTEN regulates PLK1 and controls chromosomal stability during cell division Suppression of T-cell lymphomagenesis in mice requires PTEN phosphatase activity.Distinct subtypes of genomic PTEN deletion size influence the landscape of aneuploidy and outcome in prostate cancer.PTEN regulates spindle assembly checkpoint timing through MAD1 in interphase.RCC2 is a novel p53 target in suppressing metastasis.PTEN in the maintenance of genome integrity: From DNA replication to chromosome segregation.PTEN at the interface of immune tolerance and tumor suppression.

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PTEN C-terminal deletion causes genomic instability and tumor development.

http://www.wikidata.org/entity/Q33874805

description

2014 nî lūn-bûn

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2014 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի փետրվարին հրատարակված գիտական հոդված

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年论文

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name

PTEN C-terminal deletion causes genomic instability and tumor development.

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PTEN C-terminal deletion causes genomic instability and tumor development.

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type

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PTEN C-terminal deletion causes genomic instability and tumor development.

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PTEN C-terminal deletion causes genomic instability and tumor development.

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PTEN C-terminal deletion causes genomic instability and tumor development.

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PTEN C-terminal deletion causes genomic instability and tumor development.

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PTEN C-terminal deletion causes genomic instability and tumor development.

@en

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Chuanxin Huang

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Jinxue He

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Kristy L Lamb

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Tingting Gu

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Xi Kang

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Yuxin Yin

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Zhuo Sun

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P2860

The tumor-suppressor activity of PTEN is regulated by its carboxyl-terminal region

The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate

PtdIns(3,4,5)P(3)-dependent and -independent roles for PTEN in the control of cell migration

Targeted deletion of Wwox reveals a tumor suppressor function

Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis

PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer

PTEN: life as a tumor suppressor

Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers

Initiation of genome instability and preneoplastic processes through loss of Fhit expression

Pten is essential for embryonic development and tumour suppression

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10.1016/J.CELREP.2014.01.030

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