Respiratory syncytial virus nonstructural proteins NS1 and NS2 mediate inhibition of Stat2 expression and alpha/beta interferon responsiveness
about
Human respiratory syncytial virus nonstructural protein NS2 antagonizes the activation of beta interferon transcription by interacting with RIG-IDevelopment of next-generation respiratory virus vaccines through targeted modifications to viral immunomodulatory genesAnimal models of respiratory syncytial virus infection and diseaseRespiratory syncytial virus infection in cattleRespiratory syncytial virus NS1 protein colocalizes with mitochondrial antiviral signaling protein MAVS following infectionThe non-structural NS1 protein unique to respiratory syncytial virus: a two-state folding monomer in quasi-equilibrium with a stable spherical oligomerRespiratory syncytial virus human experimental infection model: provenance, production, and sequence of low-passaged memphis-37 challenge virusSevere respiratory syncytial virus bronchiolitis in infants is associated with reduced airway interferon gamma and substance P.Respiratory syncytial virus impairs macrophage IFN-alpha/beta- and IFN-gamma-stimulated transcription by distinct mechanisms.Respiratory infections by HMPV and RSV are clinically indistinguishable but induce different host response in aged individuals.Respiratory syncytial virus interferon antagonist NS1 protein suppresses and skews the human T lymphocyte responseRespiratory syncytial virus engineered to express the cystic fibrosis transmembrane conductance regulator corrects the bioelectric phenotype of human cystic fibrosis airway epithelium in vitro.Human metapneumovirus inhibits IFN-β signaling by downregulating Jak1 and Tyk2 cellular levels.Innate immune recognition of respiratory syncytial virus infection.Refining the balance of attenuation and immunogenicity of respiratory syncytial virus by targeted codon deoptimization of virulence genesViral and host factors determine innate immune responses in airway epithelial cells from children with wheeze and atopy.Respiratory syncytial virus infections in the adult asthmatic--mechanisms of host susceptibility and viral subversion.Vaccinia virus blocks Stat1-dependent and Stat1-independent gene expression induced by type I and type II interferons.Blocking airway mucous cell metaplasia by inhibiting EGFR antiapoptosis and IL-13 transdifferentiation signals.The infectious march: the complex interaction between microbes and the immune system in asthma.Current concepts and progress in RSV vaccine development.The airway epithelium: soldier in the fight against respiratory virusesBiological challenges and technological opportunities for respiratory syncytial virus vaccine development.Molecular Mechanisms of Innate Immune Inhibition by Non-Segmented Negative-Sense RNA Viruses.Development of a reverse genetics system for respiratory syncytial virus long strain and an immunogenicity study of the recombinant virus.A systems-based approach to analyse the host response in murine lung macrophages challenged with respiratory syncytial virus.A comprehensive proteomic view of responses of A549 type II alveolar epithelial cells to human respiratory syncytial virus infectionThe NS2 protein of human respiratory syncytial virus suppresses the cytotoxic T-cell response as a consequence of suppressing the type I interferon responseRespiratory syncytial virus induced type I IFN production by pDC is regulated by RSV-infected airway epithelial cells, RSV-exposed monocytes and virus specific antibodiesMutation of the elongin C binding domain of human respiratory syncytial virus non-structural protein 1 (NS1) results in degradation of NS1 and attenuation of the virus.Both nonstructural proteins NS1 and NS2 of pneumonia virus of mice are inhibitors of the interferon type I and type III responses in vivo.Host epithelial-viral interactions as cause and cure for asthma.Exploratory Spatial Analysis of in vitro Respiratory Syncytial Virus Co-infections.Progress in understanding and controlling respiratory syncytial virus: still crazy after all these yearsReduced inflammation and altered innate response in neonates during paramyxoviral infectionMouse STAT2 restricts early dengue virus replicationAntiviral IFN-γ responses of monocytes at birth predict respiratory tract illness in the first year of lifeIdentification of a novel virulence factor in recombinant pneumonia virus of mice.Differential type I interferon induction by respiratory syncytial virus and influenza a virus in vivo.Asthma as a chronic disease of the innate and adaptive immune systems responding to viruses and allergens
P2860
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P2860
Respiratory syncytial virus nonstructural proteins NS1 and NS2 mediate inhibition of Stat2 expression and alpha/beta interferon responsiveness
description
2005 nî lūn-bûn
@nan
2005 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Respiratory syncytial virus no ...... beta interferon responsiveness
@ast
Respiratory syncytial virus no ...... beta interferon responsiveness
@en
type
label
Respiratory syncytial virus no ...... beta interferon responsiveness
@ast
Respiratory syncytial virus no ...... beta interferon responsiveness
@en
prefLabel
Respiratory syncytial virus no ...... beta interferon responsiveness
@ast
Respiratory syncytial virus no ...... beta interferon responsiveness
@en
P2860
P1433
P1476
Respiratory syncytial virus no ...... beta interferon responsiveness
@en
P2093
Mindy S Lo
Robert M Brazas
P2860
P304
P356
10.1128/JVI.79.14.9315-9319.2005
P577
2005-07-01T00:00:00Z