DNA-binding and transactivation activities are essential for TAp63 protein degradation. - Wikidata - wikimedia - TriplyDB

DNA-binding and transactivation activities are essential for TAp63 protein degradation.

DNA-binding and transactivation activities are essential for TAp63 protein degradation.

http://www.wikidata.org/entity/Q33884223

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PKCδ stabilizes TAp63 to promote cell apoptosis DNA damage in oocytes induces a switch of the quality control factor TAp63α from dimer to tetramer Mechanisms of transcriptional repression of cell-cycle G2/M promoters by p63.Epigenetic Regulation of Epidermal Stem Cell Biomarkers and Their Role in Wound Healing Differences in the transactivation domains of p53 family members: a computational study.Regulation of p63 protein stability via ubiquitin-proteasome pathway.The human papillomavirus E6 oncogene represses a cell adhesion pathway and disrupts focal adhesion through degradation of TAp63β upon transformation An invertebrate mdm homolog interacts with p53 and is differentially expressed together with p53 and ras in neoplastic Mytilus trossulus haemocytes.TAp63γ demethylation regulates protein stability and cellular distribution during neural stem cell differentiation The C-terminus of p63 contains multiple regulatory elements with different functions.Ubiquitin and ubiquitin-like modifications of the p53 family.Role of p63 in Development, Tumorigenesis and Cancer Progression p63 the guardian of human reproduction.p63 expression confers significantly better survival outcomes in high-risk diffuse large B-cell lymphoma and demonstrates p53-like and p53-independent tumor suppressor function.Quality control in oocytes by p63 is based on a spring-loaded activation mechanism on the molecular and cellular level.DeltaNp63 antagonizes p53 to regulate mesoderm induction in Xenopus laevis.Pin1 modulates p63α protein stability in regulation of cell survival, proliferation and tumor formation Anorectal malformation associated with a mutation in the P63 gene in a family with split hand-foot malformation.ΔNp63α regulates Erk signaling via MKP3 to inhibit cancer metastasis.The role of p63 in cancer, stem cells and cancer stem cells.Phosphorylation and stabilization of TAp63gamma by IkappaB kinase-beta.Characterization of specific p63 and p63-N-terminal isoform antibodies and their application for immunohistochemistry.A novel approach to cancer treatment using structural hybrids of the p53 gene family.p63 regulates an adhesion programme and cell survival in epithelial cells.The metastasis suppressor, N-myc downstream regulated gene 1 (NDRG1), upregulates p21 via p53-independent mechanisms.

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DNA-binding and transactivation activities are essential for TAp63 protein degradation.

http://www.wikidata.org/entity/Q33884223

description

2005 nî lūn-bûn

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2005 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

2005 թվականի հուլիսին հրատարակված գիտական հոդված

@hy

2005年の論文

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2005年論文

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2005年論文

@zh-hant

2005年論文

@zh-hk

2005年論文

@zh-mo

2005年論文

@zh-tw

2005年论文

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name

DNA-binding and transactivation activities are essential for TAp63 protein degradation.

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DNA-binding and transactivation activities are essential for TAp63 protein degradation.

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type

label

DNA-binding and transactivation activities are essential for TAp63 protein degradation.

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DNA-binding and transactivation activities are essential for TAp63 protein degradation.

@en

prefLabel

DNA-binding and transactivation activities are essential for TAp63 protein degradation.

@ast

DNA-binding and transactivation activities are essential for TAp63 protein degradation.

@en

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P356

MCB.25.14.6154-6164.2005

P1433

Molecular and Cellular Biology

P1476

DNA-binding and transactivation activities are essential for TAp63 protein degradation

@en

P2093

Donny L F Chang

http://www.w3.org/2001/XMLSchema#string

Frank McKeon

http://www.w3.org/2001/XMLSchema#string

Haoqiang Ying

http://www.w3.org/2001/XMLSchema#string

Zhi-Xiong Jim Xiao

http://www.w3.org/2001/XMLSchema#string

P2860

p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities

Structure of the MDM2 oncoprotein bound to the p53 tumor suppressor transactivation domain

Cloning and functional analysis of human p51, which structurally and functionally resembles p53

A C-terminal inhibitory domain controls the activity of p63 by an intramolecular mechanism.

Mdm2 promotes the rapid degradation of p53

The p63 gene in EEC and other syndromes

Site-directed mutagenesis by overlap extension using the polymerase chain reaction

Regulation of p53 stability by Mdm2

Heterozygous germline mutations in the p53 homolog p63 are the cause of EEC syndrome

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6154-6164

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scholarly article

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10.1128/MCB.25.14.6154-6164.2005

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