Deregulation of MYCN, LIN28B and LET7 in a molecular subtype of aggressive high-grade serous ovarian cancers. - Wikidata - wikimedia - TriplyDB

Deregulation of MYCN, LIN28B and LET7 in a molecular subtype of aggressive high-grade serous ovarian cancers.

Deregulation of MYCN, LIN28B and LET7 in a molecular subtype of aggressive high-grade serous ovarian cancers.

http://www.wikidata.org/entity/Q33886925

about

Circulating micro-RNAs as potential blood-based markers for early stage breast cancer detection Ovarian cancer cell invasiveness is associated with discordant exosomal sequestration of Let-7 miRNA and miR-200 MYC and the art of microRNA maintenance Regulation of ovarian cancer stem cells or tumor-initiating cells A KRAS variant is a biomarker of poor outcome, platinum chemotherapy resistance and a potential target for therapy in ovarian cancer Focal DNA copy number changes in neuroblastoma target MYCN regulated genes Unveiling MYCN regulatory networks in neuroblastoma via integrative analysis of heterogeneous genomics data.11q deletion in neuroblastoma: a review of biological and clinical implications.Anti-miR182 reduces ovarian cancer burden, invasion, and metastasis: an in vivo study in orthotopic xenografts of nude mice.ABCA transporter gene expression and poor outcome in epithelial ovarian cancer.ARID3B induces tumor necrosis factor alpha mediated apoptosis while a novel ARID3B splice form does not induce cell death.Profiles of genomic instability in high-grade serous ovarian cancer predict treatment outcome LIN28B promotes colon cancer migration and recurrence.OvMark: a user-friendly system for the identification of prognostic biomarkers in publically available ovarian cancer gene expression datasets.The Wnt gatekeeper SFRP4 modulates EMT, cell migration and downstream Wnt signalling in serous ovarian cancer cells High levels of genomic aberrations in serous ovarian cancers are associated with better survival.Combined image and genomic analysis of high-grade serous ovarian cancer reveals PTEN loss as a common driver event and prognostic classifier An in-tumor genetic screen reveals that the BET bromodomain protein, BRD4, is a potential therapeutic target in ovarian carcinoma Molecular correlates of platinum response in human high-grade serous ovarian cancer patient-derived xenografts Expression of CIP2A in renal cell carcinomas correlates with tumour invasion, metastasis and patients' survival.Loss of let-7 up-regulates EZH2 in prostate cancer consistent with the acquisition of cancer stem cell signatures that are attenuated by BR-DIM Aberrant regulation of the LIN28A/LIN28B and let-7 loop in human malignant tumors and its effects on the hallmarks of cancer Overexpression of the RNA-binding proteins Lin28B and IGF2BP3 (IMP3) is associated with chemoresistance and poor disease outcome in ovarian cancer.The MYCN-HMGA2-CDKN2A pathway in non-small cell lung carcinoma--differences in histological subtypes Lin-28 homologue A (LIN28A) promotes cell cycle progression via regulation of cyclin-dependent kinase 2 (CDK2), cyclin D1 (CCND1), and cell division cycle 25 homolog A (CDC25A) expression in cancer Tandem duplication of chromosomal segments is common in ovarian and breast cancer genomes Defining Transcriptional Regulatory Mechanisms for Primary let-7 miRNAs Attributes of Oct4 in stem cell biology: perspectives on cancer stem cells of the ovary.A LIN28B polymorphism predicts for colon cancer survival.PI3K/AKT/mTOR and sonic hedgehog pathways cooperate together to inhibit human pancreatic cancer stem cell characteristics and tumor growth.Differential miRNA expression profiles between the first and third trimester human placentas MYCN-driven regulatory mechanisms controlling LIN28B in neuroblastoma Lin28 promotes growth of prostate cancer cells and activates the androgen receptor Functional genomics identifies five distinct molecular subtypes with clinical relevance and pathways for growth control in epithelial ovarian cancer.LIN28 Expression in malignant germ cell tumors downregulates let-7 and increases oncogene levels LIN28B-mediated expression of fetal hemoglobin and production of fetal-like erythrocytes from adult human erythroblasts ex vivo MicroRNA profiling of carcinogen-induced rat colon tumors and the influence of dietary spinach.Neuroblastoma and MYCN Molecular characteristics of malignant ovarian germ cell tumors and comparison with testicular counterparts: implications for pathogenesis.Expression of cancerous inhibitor of protein phosphatase 2A in human triple negative breast cancer correlates with tumor survival, invasion and autophagy.

P2860

Q21134914-9EC4C0B9-58A4-4F85-86B2-B10E4AF7AC0C Q24616100-39237588-DC70-4D42-940E-D6B0C4BC1373 Q26825457-81DFF496-3464-4C47-AD68-EC933F7D4C6A Q26853096-4E59A43C-59D5-4D99-8C76-63A8EB301BA9 Q27851690-906960F4-3FFA-44B1-A96E-2FF97ABDCBC5 Q28115604-B6D91DCA-24F4-417C-BC5E-B4D551FCD761 Q31095310-B519E939-00EA-4274-BF00-7E6765784B61 Q32174267-B1F58945-91A4-48CA-A709-7D8BBDC7667C Q33895739-90623C8A-5A26-457A-95C4-48F1885FED0A Q33947899-64FC64AA-825E-4CDB-BB75-34691804DFF0 Q34364547-267AF8DD-1E80-4A4A-A45A-92254625089B Q34381630-31E92805-7994-4F57-9544-E1C63820B921 Q34433950-DE986768-ECF4-4B49-A66B-E7FF5FA55A4E Q34447404-3CAE4089-B1E2-494E-AAF4-EF17A4B453A2 Q34552289-65B02E52-E343-406D-A104-76E53381D99B Q34571142-A64F4C71-64D7-4582-AE80-76425C7B37F0 Q34720998-23796548-ACCC-425F-A4FF-DF1CFCEE73F5 Q34926232-5B99E197-C462-46D0-8357-7D19A9C8121A Q35448716-0968638F-CA1E-4761-837B-9782FC284FE2 Q35653981-496C7E19-B47B-4B68-B289-5D34C333FC13 Q35839941-7A75D7B0-842D-4548-89D9-DD3B6228C514 Q35881362-BDD7FCE6-0E35-454A-89A8-FDAE7ADAA0DB Q35909674-5AF27AC8-F24D-4835-B05A-BC3FA2EA3433 Q35917825-9D51DB24-98FC-4C0A-B75B-DD822361242E Q36006947-BEEF7358-3739-4223-9814-55FF8A48F2C7 Q36193230-384EB06B-C092-4D14-A12D-D953AA3410C2 Q36239451-8E16F064-CBAC-4FD9-9765-DA8B8F85D8C5 Q36507476-082D2A99-B25A-48B1-A75D-928AA4025BD3 Q36524197-D3842BDB-A593-44F2-96DB-7D9AE1E01D8A Q36544764-518E3712-84B9-4383-8364-08C401207EEE Q36764042-E0721957-842B-44EE-BA67-9E5E8B755C00 Q36815139-0EBFFABA-0C06-485A-903C-ADF2A02AAA60 Q36986508-A205CCB5-606E-4D47-B437-7DF5EB7382C4 Q37040827-EAEAE6FC-5CD7-4661-AE11-4629B100680F Q37067208-E1FD5864-A489-424D-A9F1-D60D79D9BEFF Q37083933-17FA4A5D-6208-4904-BC41-282AA827B34C Q37146244-718D6F8C-AF1F-49EA-8BD3-24BA8DD68449 Q37201479-A425D238-A584-40CF-A8FA-C6F4DBB18A9C Q37209628-7908947B-9030-4D2C-9572-8A4F93C78F09 Q37581930-1FE57D04-AFB9-4164-929F-80F828B72146

P2860

Deregulation of MYCN, LIN28B and LET7 in a molecular subtype of aggressive high-grade serous ovarian cancers.

http://www.wikidata.org/entity/Q33886925

description

2011 nî lūn-bûn

@nan

2011 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի ապրիլին հրատարակված գիտական հոդված

@hy

2011年の論文

@ja

2011年学术文章

@wuu

2011年学术文章

@zh-cn

2011年学术文章

@zh-hans

2011年学术文章

@zh-my

2011年学术文章

@zh-sg

2011年學術文章

@yue

name

Deregulation of MYCN, LIN28B a ...... -grade serous ovarian cancers.

@ast

Deregulation of MYCN, LIN28B a ...... -grade serous ovarian cancers.

@en

type

label

Deregulation of MYCN, LIN28B a ...... -grade serous ovarian cancers.

@ast

Deregulation of MYCN, LIN28B a ...... -grade serous ovarian cancers.

@en

prefLabel

Deregulation of MYCN, LIN28B a ...... -grade serous ovarian cancers.

@ast

Deregulation of MYCN, LIN28B a ...... -grade serous ovarian cancers.

@en

P1433

Q33886925-8F8C5BAC-7BF0-4CD7-B61C-AF082C219757

P1476

Q33886925-20C73358-CD3F-4F75-A30C-DF3B6FBD9079

P2093

Q33886925-1C9A521A-236F-421D-9D38-493B871E76BB

Q33886925-20E5DD08-EE49-4884-8C75-7373DC1FF255

Q33886925-3AAA575F-710A-4E44-911F-3855A9D65B69

Q33886925-3AB48224-FC9D-4940-ACF1-A4C67EA1AC19

Q33886925-6BE888B8-AF72-4056-A6B1-40394F14450D

Q33886925-79F80189-B78E-4D4E-BB1D-A6830DCB2F21

Q33886925-8C8B2DFE-7104-4B62-BB00-A08DCFC10ED5

Q33886925-8F3B4E9A-2C97-4ECB-86AA-FA94469DA984

Q33886925-94A8B572-7BDB-4260-B316-F6CF447E55BB

Q33886925-97CC56BA-530A-4866-822E-C209B36DA9EB

P2860

Q33886925-01A24D2D-994D-453A-912D-46A9849E06A8

Q33886925-15EDB9A5-C811-4DB9-8247-29D8F8523908

Q33886925-1A2D6C91-20D6-4EAB-B4BC-6876DAAE9E70

Q33886925-1BA2D57D-EFC1-44E9-BA54-93A05A6A6CE7

Q33886925-21DA0AC0-C286-4B58-A687-CD49D51A9ECB

Q33886925-221EFA8E-A470-45CD-9061-2F1ED3BBC4E2

Q33886925-240B3CB4-79D9-43E4-A347-E621C27EF864

Q33886925-2783386E-E0B2-4F9F-A00F-DA4CACB45D38

Q33886925-2E3D7101-C625-43CC-AB75-349B2FAED9C1

Q33886925-30A5260F-C7D0-42DE-A829-011EDCE7B72E

P304

Q33886925-43BB41E3-EDA0-4C7C-A4AC-CBB18EC7167E

P31

Q33886925-A143FE74-1F32-4AE3-BB5A-63E5D2EAA6DD

P356

Q33886925-6B40D6CD-CC4E-457B-94E3-8540D6CC7B05

P407

Q33886925-C50F4EC1-DADF-4296-A50A-059A6F1A7F07

P433

Q33886925-DFB05FEE-E383-4926-BA5B-6885E66B9C77

P478

Q33886925-4E3D3B02-3D18-47EC-89D0-E810F8870E19

P50

Q33886925-0952F461-BEE5-40FE-8068-5F0B51BE8673

Q33886925-1D9AD2A1-8EFB-4BE6-A41E-DD05FDECE3B6

Q33886925-2B228B91-ACE5-4C9F-8F52-8E164B32C84C

Q33886925-36EFF0C8-98FC-4831-8837-9CFE24D61977

Q33886925-401068ED-9D98-4F43-B340-8B743C5B1D8E

Q33886925-8866CBC0-71BE-42A2-98C0-7CE652C6CFF8

Q33886925-CD6CBC81-7A35-4EF8-AC24-EC645537E91A

Q33886925-CE119FFF-67FC-4A0C-9E26-C4CA0FA7C091

Q33886925-DF0DC479-979D-4359-A50A-6102567908DD

Q33886925-FDE34F19-7783-4044-A7F0-F560FC2B2F32

P577

Q33886925-22634F52-89A3-4CFE-93C6-439525816261

P5875

Q33886925-047FBD0A-B487-4B8B-8260-DF822177E675

P698

Q33886925-A881B4A6-E9BF-457A-9ED3-8A09B3825709

P921

Q33886925-D59D82FF-BD59-48BB-800B-0A9101961154

P932

Q33886925-4FB2969A-42FD-4595-879D-BB24C72DCB74

P356

JOURNAL.PONE.0018064

P1433

P1476

Deregulation of MYCN, LIN28B a ...... -grade serous ovarian cancers.

@en

P2093

Anil K Rustgi

http://www.w3.org/2001/XMLSchema#string

Cameron N Johnstone

http://www.w3.org/2001/XMLSchema#string

Chad J Creighton

http://www.w3.org/2001/XMLSchema#string

Colin M House

http://www.w3.org/2001/XMLSchema#string

Dariush Etemadmoghadam

http://www.w3.org/2001/XMLSchema#string

David G Huntsman

http://www.w3.org/2001/XMLSchema#string

Gunnar B Kristensen

http://www.w3.org/2001/XMLSchema#string

Joshy George

http://www.w3.org/2001/XMLSchema#string

Michael J Birrer

http://www.w3.org/2001/XMLSchema#string

Nataliya Melnyk

http://www.w3.org/2001/XMLSchema#string

P2860

Ovarian carcinoma subtypes are different diseases: implications for biomarker studies

Lin28 mediates the terminal uridylation of let-7 precursor MicroRNA

A feedback loop comprising lin-28 and let-7 controls pre-let-7 maturation during neural stem-cell commitment

MicroRNAs: target recognition and regulatory functions

Overexpression of dicer as a result of reduced let-7 MicroRNA levels contributes to increased cell proliferation of oral cancer cells

Lin-28B transactivation is necessary for Myc-mediated let-7 repression and proliferation

Lin-28 interaction with the Let-7 precursor loop mediates regulated microRNA processing

Let-7 and miR-200 microRNAs: guardians against pluripotency and cancer progression

Most mammalian mRNAs are conserved targets of microRNAs

Hmga2 promotes neural stem cell self-renewal in young but not old mice by reducing p16Ink4a and p19Arf Expression

P304

e18064

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1371/JOURNAL.PONE.0018064

http://www.w3.org/2001/XMLSchema#string

P407

P433

4

http://www.w3.org/2001/XMLSchema#string

P478

6

http://www.w3.org/2001/XMLSchema#string

P50

Anne-Lise Børresen-Dale

Wayne A. Phillips

Åslaug Helland

Australian Ovarian Cancer Study Group

Michael S Anglesio

Karen E Sheppard

P577

2011-04-13T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

51089477

http://www.w3.org/2001/XMLSchema#string

P698

21533284

http://www.w3.org/2001/XMLSchema#string

P921

P932

3076323

http://www.w3.org/2001/XMLSchema#string