Focal radiation therapy combined with 4-1BB activation and CTLA-4 blockade yields long-term survival and a protective antigen-specific memory response in a murine glioma model. - Wikidata - wikimedia - TriplyDB

Focal radiation therapy combined with 4-1BB activation and CTLA-4 blockade yields long-term survival and a protective antigen-specific memory response in a murine glioma model.

Focal radiation therapy combined with 4-1BB activation and CTLA-4 blockade yields long-term survival and a protective antigen-specific memory response in a murine glioma model.

http://www.wikidata.org/entity/Q33889603

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Radiotherapy combination opportunities leveraging immunity for the next oncology practice Immunotherapy for cancer in the central nervous system: Current and future directions Immune Evasion Strategies of Glioblastoma Radio-Immunotherapy-Induced Immunogenic Cancer Cells as Basis for Induction of Systemic Anti-Tumor Immune Responses - Pre-Clinical Evidence and Ongoing Clinical Applications Strategies for combining immunotherapy with radiation for anticancer therapy Immunosuppressive Mechanisms of Malignant Gliomas: Parallels at Non-CNS Sites 4-1BB Agonists: Multi-Potent Potentiators of Tumor Immunity Combination Approaches with Immune-Checkpoint Blockade in Cancer Therapy Combining Radiation Therapy with Immune Checkpoint Blockade for Central Nervous System Malignancies Targeting immune checkpoints in malignant glioma Prospects of immune checkpoint modulators in the treatment of glioblastoma TGF-β signaling and its targeting for glioma treatment Concepts of immunotherapy for glioma Immunotherapy and radiation therapy for operable early stage and locally advanced non-small cell lung cancer Combinations of immunotherapy and radiation in cancer therapy.Optimizing Timing of Immunotherapy Improves Control of Tumors by Hypofractionated Radiation Therapy.Therapeutic administration of IL-15 superagonist complex ALT-803 leads to long-term survival and durable antitumor immune response in a murine glioblastoma model.PD-1 blockade attenuates immunosuppressive myeloid cells due to inhibition of CD47/SIRPα axis in HPV negative head and neck squamous cell carcinoma.Stereotactic radiation therapy combined with immunotherapy: augmenting the role of radiation in local and systemic treatment.Agonist anti-GITR monoclonal antibody and stereotactic radiation induce immune-mediated survival advantage in murine intracranial glioma.Immunotherapy in glioblastoma: emerging options in precision medicine Prioritization schema for immunotherapy clinical trials in glioblastoma.The intersection of radiotherapy and immunotherapy: mechanisms and clinical implications.Immune checkpoint combinations from mouse to man.Genetics and immunotherapy: using the genetic landscape of gliomas to inform management strategies.Combining immunotherapy with radiation for the treatment of glioblastoma.Preclinical efficacy of immune-checkpoint monotherapy does not recapitulate corresponding biomarkers-based clinical predictions in glioblastoma.Prostate Cancer Immunotherapy with Sipuleucel-T: Current Standards and Future Directions.Immunotherapy Combined with Large Fractions of Radiotherapy: Stereotactic Radiosurgery for Brain Metastases-Implications for Intraoperative Radiotherapy after Resection.Clinical Trials Investigating Immune Checkpoint Blockade in Glioblastoma.Combining radiotherapy with immunotherapy: the past, the present and the future.Deciphering CD137 (4-1BB) signaling in T-cell costimulation for translation into successful cancer immunotherapy.Effect of pterostilbene on glioma cells and related mechanisms.Therapeutic Hypothesis Testing With Rodent Brain Tumor Models.Irradiation and immunotherapy: From concept to the clinic.Immunotherapy and radiation in glioblastoma.Combination Therapy with Anti-PD-1, Anti-TIM-3, and Focal Radiation Results in Regression of Murine Gliomas.Neural stem cells, the subventricular zone and radiotherapy: implications for treating glioblastoma.Checkpoint inhibition in meningiomas.Developing immunotherapeutic strategies to target brain tumors.

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Focal radiation therapy combined with 4-1BB activation and CTLA-4 blockade yields long-term survival and a protective antigen-specific memory response in a murine glioma model.

http://www.wikidata.org/entity/Q33889603

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2014 nî lūn-bûn

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2014年の論文

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P2860

Safety, activity, and immune correlates of anti-PD-1 antibody in cancer

Molecular detection of tumor-associated antigens shared by human cutaneous melanomas and gliomas

Nivolumab plus ipilimumab in advanced melanoma.

The blockade of immune checkpoints in cancer immunotherapy

Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma

Improved Survival with Ipilimumab in Patients with Metastatic Melanoma

Ipilimumab plus dacarbazine for previously untreated metastatic melanoma

Enhancement of antitumor immunity by CTLA-4 blockade

Combination CTLA-4 blockade and 4-1BB activation enhances tumor rejection by increasing T-cell infiltration, proliferation, and cytokine production

Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial

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