Combination Therapy with Anti-PD-1, Anti-TIM-3, and Focal Radiation Results in Regression of Murine Gliomas.
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Immunotherapy of Malignant Tumors in the Brain: How Different from Other Sites?Cancer immunotherapy: how low-level ionizing radiation can play a key role.Elevated frequencies of CD8 T cells expressing PD-1, CTLA-4 and Tim-3 within tumour from perineural squamous cell carcinoma patients.Small molecules targeting histone demethylase genes (KDMs) inhibit growth of temozolomide-resistant glioblastoma cellsTim-3 and PD-1 regulate CD8+ T cell function to maintain early pregnancy in mice.Preclinical efficacy of immune-checkpoint monotherapy does not recapitulate corresponding biomarkers-based clinical predictions in glioblastoma.Immunotherapy Combined with Large Fractions of Radiotherapy: Stereotactic Radiosurgery for Brain Metastases-Implications for Intraoperative Radiotherapy after Resection.Clinical Trials Investigating Immune Checkpoint Blockade in Glioblastoma.Characterization of PD-1 upregulation on tumor-infiltrating lymphocytes in human and murine gliomas and preclinical therapeutic blockade.Immunotherapy and radiation in glioblastoma.Correlation of immune phenotype with IDH mutation in diffuse glioma.The Role of Immune Checkpoint Inhibition in the Treatment of Brain Tumors.Immune Checkpoint Blockade Biology in Mouse Models of Glioblastoma.Co-inhibitory blockade while preserving tolerance: checkpoint inhibitors for glioblastoma.Current modalities in cancer immunotherapy: Immunomodulatory antibodies, CARs and vaccines.PD-1/PD-L1 inhibitors in haematological malignancies: update 2017.A TIM-3 Oligonucleotide Aptamer Enhances T Cell Functions and Potentiates Tumor Immunity in Mice.Combined immunotherapy with anti-PDL-1/PD-1 and anti-CD4 antibodies cures syngeneic disseminated neuroblastoma.Immunotherapy with subcutaneous immunogenic autologous tumor lysate increases murine glioblastoma survival.Ly6Clo monocytes drive immunosuppression and confer resistance to anti-VEGFR2 cancer therapy.Molecular and clinical characterization of TIM-3 in glioma through 1,024 samples.Focused Ultrasound Immunotherapy for Central Nervous System Pathologies: Challenges and Opportunities.Radiation enhanced the local and distant anti-tumor efficacy in dual immune checkpoint blockade therapy in osteosarcoma.Tumor-infiltrating CD4+ T cells in patients with gastric cancer.Modeling tumor immunity of mouse glioblastoma by exhausted CD8+ T cells.Eight-Color Multiplex Immunohistochemistry for Simultaneous Detection of Multiple Immune Checkpoint Molecules within the Tumor Microenvironment.Agonist OX40 immunotherapy improves survival in glioma-bearing mice and is complementary with vaccination with irradiated GM-CSF-expressing tumor cells.Radiation effects on antitumor immune responses: current perspectives and challenges.Immunotherapies for malignant glioma.Incorporating Radiation Oncology into Immunotherapy: proceedings from the ASTRO-SITC-NCI immunotherapy workshop.Repurposing tin mesoporphyrin as an immune checkpoint inhibitor shows therapeutic efficacy in preclinical models of cancer.T Cell Exhaustion Signatures Vary with Tumor Type and are Severe in Glioblastoma.ID(H)entifying checkpoint inhibitor candidates among diffuse glioma.Current state and future prospects of immunotherapy for glioma.T-Cell Dysfunction in Glioblastoma: Applying a New Framework.CNS cancer immunity cycle and strategies to target this for glioblastoma.Future of anti-PD-1/PD-L1 applications: Combinations with other therapeutic regimens.Molecular and clinical characterization of PTPN2 expression from RNA-seq data of 996 brain gliomas.Radiation therapy and PD-1/PD-L1 blockade: the clinical development of an evolving anticancer combination.Tim-3 expression and its role in hepatocellular carcinoma
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P2860
Combination Therapy with Anti-PD-1, Anti-TIM-3, and Focal Radiation Results in Regression of Murine Gliomas.
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
2016年论文
@zh
2016年论文
@zh-cn
name
Combination Therapy with Anti- ...... Regression of Murine Gliomas.
@en
type
label
Combination Therapy with Anti- ...... Regression of Murine Gliomas.
@en
prefLabel
Combination Therapy with Anti- ...... Regression of Murine Gliomas.
@en
P2093
P2860
P1476
Combination Therapy with Anti- ...... Regression of Murine Gliomas.
@en
P2093
Alessandro Olivi
Allison M Martin
Antonella Mangraviti
Betty M Tyler
Charles G Drake
Christopher M Jackson
Debebe Theodros
Dimitrios Mathios
P2860
P304
P356
10.1158/1078-0432.CCR-15-1535
P407
P577
2016-06-29T00:00:00Z