mRNA and microRNA expression profiles of the NCI-60 integrated with drug activities
about
Putative DNA/RNA helicase Schlafen-11 (SLFN11) sensitizes cancer cells to DNA-damaging agentsUsing CellMiner 1.6 for Systems Pharmacology and Genomic Analysis of the NCI-60Strategic applications of gene expression: from drug discovery/development to bedsideUsing drug response data to identify molecular effectors, and molecular "omic" data to identify candidate drugs in cancerIdentification of a predominant co-regulation among kinetochore genes, prospective regulatory elements, and association with genomic instabilityGenome-wide analysis of miRNA signature differentially expressed in doxorubicin-resistant and parental human hepatocellular carcinoma cell linesNCI-60 whole exome sequencing and pharmacological CellMiner analysesHigh resolution copy number variation data in the NCI-60 cancer cell lines from whole genome microarrays accessible through CellMinerBioinformatics of Cancer ncRNA in High Throughput Sequencing: Present State and ChallengesGenome-wide mRNA and microRNA profiling of the NCI 60 cell-line screen and comparison of FdUMP[10] with fluorouracil, floxuridine, and topoisomerase 1 poisonsThe NCI-60 Methylome and Its Integration into CellMiner.Multilevel omic data integration in cancer cell lines: advanced annotation and emergent properties.Gene expression profiling of 49 human tumor xenografts from in vitro culture through multiple in vivo passages--strategies for data mining in support of therapeutic studies.MDP, a database linking drug response data to genomic information, identifies dasatinib and statins as a combinatorial strategy to inhibit YAP/TAZ in cancer cellsEvaluation of O2PLS in Omics data integrationHandling missing rows in multi-omics data integration: multiple imputation in multiple factor analysis framework.A multivariate approach to the integration of multi-omics datasetsComputational prediction of intronic microRNA targets using host gene expression reveals novel regulatory mechanisms.Cellular stress induced alterations in microRNA let-7a and let-7b expression are dependent on p53Deciphering causal and statistical relations of molecular aberrations and gene expressions in NCI-60 cell lines.Estimating the activity of transcription factors by the effect on their target genesFunctional categories associated with clusters of genes that are co-expressed across the NCI-60 cancer cell linesMicroRNA regulation of expression of the cystic fibrosis transmembrane conductance regulator geneA novel network integrating a miRNA-203/SNAI1 feedback loop which regulates epithelial to mesenchymal transition.Gene expression profiles of the NCI-60 human tumor cell lines define molecular interaction networks governing cell migration processesToward a combinatorial nature of microRNA regulation in human cellsA least angle regression model for the prediction of canonical and non-canonical miRNA-mRNA interactions.A p-Median approach for predicting drug response in tumour cells.The expression levels of microRNA-361-5p and its target VEGFA are inversely correlated in human cutaneous squamous cell carcinomaExpression of microRNAs in the NCI-60 cancer cell-linesLarge-scale modeling of condition-specific gene regulatory networks by information integration and inference.Feature selection and classifier performance on diverse bio- logical datasetsGlobal microRNA level regulation of EGFR-driven cell-cycle protein network in breast cancer.MicroRNA signatures as biomarkers and therapeutic target for CNS embryonal tumors: the pros and the cons.MicroRNA-433 negatively regulates the expression of thymidylate synthase (TYMS) responsible for 5-fluorouracil sensitivity in HeLa cells.Direct quantification of mRNA and miRNA from cell lysates using reverse transcription real time PCR: a multidimensional analysis of the performance of reagents and workflows.Coordinated regulation of mitochondrial topoisomerase IB with mitochondrial nuclear encoded genes and MYC.High-throughput RNA profiling via up-front sample parallelization.Modulation of MicroRNAs by Chemical Carcinogens and Anticancer Drugs in Human Cancer: Potential Inkling to Therapeutic AdvantageIdentification of oncogenic microRNA-17-92/ZBTB4/specificity protein axis in breast cancer
P2860
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P2860
mRNA and microRNA expression profiles of the NCI-60 integrated with drug activities
description
2010 nî lūn-bûn
@nan
2010 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
mRNA and microRNA expression profiles of the NCI-60 integrated with drug activities
@ast
mRNA and microRNA expression profiles of the NCI-60 integrated with drug activities
@en
type
label
mRNA and microRNA expression profiles of the NCI-60 integrated with drug activities
@ast
mRNA and microRNA expression profiles of the NCI-60 integrated with drug activities
@en
prefLabel
mRNA and microRNA expression profiles of the NCI-60 integrated with drug activities
@ast
mRNA and microRNA expression profiles of the NCI-60 integrated with drug activities
@en
P2093
P2860
P1476
mRNA and microRNA expression profiles of the NCI-60 integrated with drug activities
@en
P2093
Hongfang Liu
John N Weinstein
Kurt W Kohn
Petula D'Andrade
Philip Lorenzi
Stephanie Fulmer-Smentek
William C Reinhold
P2860
P304
P356
10.1158/1535-7163.MCT-09-0965
P50
P577
2010-05-04T00:00:00Z