Asparagine synthetase as a causal, predictive biomarker for L-asparaginase activity in ovarian cancer cells.
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In vitro human cell line models to predict clinical response to anticancer drugsCIViC databaseCellMiner: a relational database and query tool for the NCI-60 cancer cell lines.DNA fingerprinting of the NCI-60 cell line panel.Multifactorial regulation of E-cadherin expression: an integrative study.The glutaminase activity of L-asparaginase is not required for anticancer activity against ASNS-negative cells.NCI60 cancer cell line panel data and RNAi analysis help identify EAF2 as a modulator of simvastatin and lovastatin response in HCT-116 cells.mRNA and microRNA expression profiles of the NCI-60 integrated with drug activitiesAsparagine synthetase: a new potential biomarker in ovarian cancer.Asparagine synthetase is a predictive biomarker of L-asparaginase activity in ovarian cancer cell lines.Targeted metabolomic analysis of amino acid response to L-asparaginase in adherent cellsA conserved glutamate controls the commitment to acyl-adenylate formation in asparagine synthetaseAsparagine synthetase: regulation by cell stress and involvement in tumor biologyPolymorphisms of asparaginase pathway and asparaginase-related complications in children with acute lymphoblastic leukemia.L-asparaginase inhibits invasive and angiogenic activity and induces autophagy in ovarian cancer.Integrative molecular profiling reveals asparagine synthetase is a target in castration-resistant prostate cancer.Asparagine synthetase is an independent predictor of surgical survival and a potential therapeutic target in hepatocellular carcinomaOverexpression of asparagine synthetase and matrix metalloproteinase 19 confers cisplatin sensitivity in nasopharyngeal carcinoma cells.Mutation analysis of 24 known cancer genes in the NCI-60 cell line set.Genomic and expression profiling of adrenocortical carcinoma: application to diagnosis, prognosis and treatment.A phase II clinical trial of polyethylene glycol-conjugated L-asparaginase in patients with advanced ovarian cancer: Early closure for safety.Asparaginase in the treatment of non-ALL hematologic malignancies.Knockdown of asparagine synthetase (ASNS) suppresses cell proliferation and inhibits tumor growth in gastric cancer cells.Knockdown of asparagine synthetase by RNAi suppresses cell growth in human melanoma cells and epidermoid carcinoma cells.Down-regulation of asparagine synthetase induces cell cycle arrest and inhibits cell proliferation of breast cancer.Expression of asparagine synthetase predicts in vitro response to L-asparaginase in canine lymphoid cell lines.Asparaginase pharmacology: challenges still to be faced.Oncogenic KRAS Regulates Amino Acid Homeostasis and Asparagine Biosynthesis via ATF4 and Alters Sensitivity to L-Asparaginase.Asparagine synthetase: Function, structure, and role in disease.Loss of asparagine synthetase suppresses the growth of human lung cancer cells by arresting cell cycle at G0/G1 phase.The crucial role of multiomic approach in cancer research and clinically relevant outcomes.Asparagine synthetase expression is associated with the sensitivity to asparaginase in extranodal natural killer/T-cell lymphoma in vivo and in vitro
P2860
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P2860
Asparagine synthetase as a causal, predictive biomarker for L-asparaginase activity in ovarian cancer cells.
description
2006 nî lūn-bûn
@nan
2006 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Asparagine synthetase as a cau ...... ivity in ovarian cancer cells.
@ast
Asparagine synthetase as a cau ...... ivity in ovarian cancer cells.
@en
Asparagine synthetase as a cau ...... ivity in ovarian cancer cells.
@nl
type
label
Asparagine synthetase as a cau ...... ivity in ovarian cancer cells.
@ast
Asparagine synthetase as a cau ...... ivity in ovarian cancer cells.
@en
Asparagine synthetase as a cau ...... ivity in ovarian cancer cells.
@nl
prefLabel
Asparagine synthetase as a cau ...... ivity in ovarian cancer cells.
@ast
Asparagine synthetase as a cau ...... ivity in ovarian cancer cells.
@en
Asparagine synthetase as a cau ...... ivity in ovarian cancer cells.
@nl
P2093
P50
P1476
Asparagine synthetase as a cau ...... ivity in ovarian cancer cells.
@en
P2093
Daniel D Von Hoff
Elise C Kohn
Gabriel S Eichler
Ivan D Horak
Joe W Gray
John N Weinstein
Mark Raffeld
Martina Rudelius
Michele Gunsior
P304
P356
10.1158/1535-7163.MCT-06-0447
P577
2006-11-01T00:00:00Z