CYP2C9-CYP3A4 protein-protein interactions: role of the hydrophobic N terminus. - Wikidata - wikimedia - TriplyDB

CYP2C9-CYP3A4 protein-protein interactions: role of the hydrophobic N terminus.

CYP2C9-CYP3A4 protein-protein interactions: role of the hydrophobic N terminus.

http://www.wikidata.org/entity/Q33891038

about

The Role of Protein-Protein and Protein-Membrane Interactions on P450 Function Identifying cytochrome p450 functional networks and their allosteric regulatory elements CYP2C9 genotype vs. metabolic phenotype for individual drug dosing--a correlation analysis using flurbiprofen as probe drug Role of protein-protein interactions in cytochrome P450-mediated drug metabolism and toxicity CYP2C8 exists as a dimer in natural membranes.Altered CYP2C9 activity following modulation of CYP3A4 levels in human hepatocytes: an example of protein-protein interactions.Cytochrome P450 system proteins reside in different regions of the endoplasmic reticulum.Interactions among cytochromes P450 in microsomal membranes: oligomerization of cytochromes P450 3A4, 3A5, and 2E1 and its functional consequences Development of an in vitro system with human liver microsomes for phenotyping of CYP2C9 genetic polymorphisms with a mechanism-based inactivator Identification of cytochrome P450 2C2 protein complexes in mouse liver.Effect of homomeric P450-P450 complexes on P450 function.Interactions between CYP2E1 and CYP2B4: effects on affinity for NADPH-cytochrome P450 reductase and substrate metabolism.Immobilized Cytochrome P450 for Monitoring of P450-P450 Interactions and Metabolism Functional studies of N-terminally modified CYP2J2 epoxygenase in model lipid bilayers Interactions between cytochromes P450 2B4 (CYP2B4) and 1A2 (CYP1A2) lead to alterations in toluene disposition and P450 uncoupling Correlating structure and function of drug-metabolizing enzymes: progress and ongoing challenges.Physical Studies of P450-P450 Interactions: Predicting Quaternary Structures of P450 Complexes in Membranes from Their X-ray Crystal Structures.Microsomal monooxygenase as a multienzyme system: the role of P450-P450 interactions.Formation of P450 · P450 complexes and their effect on P450 function The functional effects of physical interactions involving cytochromes P450: putative mechanisms of action and the extent of these effects in biological membranes.Activation of CYP3A-mediated testosterone 6β-hydroxylation by tanshinone IIA and midazolam 1-hydroxylation by cryptotanshinone in human liver microsomes.Extensive protein interactions involving cytochrome P450 3A4: a possible contributor to the formation of a metabolosome.Characterization of interactions among CYP1A2, CYP2B4, and NADPH-cytochrome P450 reductase: Identification of specific protein complexes.Toward a systems approach to the human cytochrome P450 ensemble: interactions between CYP2D6 and CYP2E1 and their functional consequences.Protein-protein and protein-membrane associations in the lignin pathway.

P2860

Q27345454-531742CC-58E1-44A6-89F2-0315C1AC9E2C Q28535773-92FCAB6D-24C6-4775-BA58-B9AB7F1D018F Q28544111-DCE00708-0F71-462E-BD42-36D82ACAFB27 Q34181972-4D215D7C-6D65-4A09-923C-9AC0215BCAF5 Q34257489-746609E8-3500-4006-8912-2E359573EE9D Q34360051-A3B51377-3557-4894-9BAD-120F783A5DBF Q35038939-35A7303E-257D-46DA-9E96-A9FAABBCFD58 Q35055663-0A35294C-AA2F-4C5E-9EE8-BD9FF3A9A9B2 Q35846894-F5F05A44-983E-49E1-AA6A-69D241ECAED1 Q35869046-86F7BE2A-E45A-4F3B-9995-E32E7EF315A9 Q36456390-7F70D825-B747-4E47-BBB0-16AD9A28C47E Q36497669-CD488A0C-24D8-4F41-B202-FE898A8EA4D5 Q36852513-7AA74AA3-6E5B-4C05-94C4-B9CD8968D5FF Q37034584-F0393EAE-FED7-42B3-8683-A93A51C663E9 Q37112456-FA2C8DF4-F638-4798-B219-56E4F44C2C7E Q37422674-6155A5E8-ABBD-4599-B7A0-999BD6F487C1 Q37611698-6F150B35-7B54-48CE-B24D-7AF50A5E3890 Q37852000-5EB33E3C-4BA9-4C6F-ACAF-D94DA2679806 Q37966569-86149E8A-038B-4DFD-97B1-0A36AD0CFE89 Q38833525-3A85F86E-DE33-423A-B6F4-12E8F940B421 Q42851622-35D77D2C-6B5B-48E5-816E-38034A08979F Q42930827-CFC00FEC-F763-4BC9-B61A-39B659F6F604 Q47301320-30851C4C-8430-4F81-83EF-EFA7F35FBDA6 Q47806908-1A16C8BA-1E73-46BD-AABA-87EA50EB62BA Q50487635-BBE214D5-4411-4F1C-991C-1BA44ACC0E36

P2860

CYP2C9-CYP3A4 protein-protein interactions: role of the hydrophobic N terminus.

http://www.wikidata.org/entity/Q33891038

description

2010 nî lūn-bûn

@nan

2010 թուականի Մարտին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի մարտին հրատարակված գիտական հոդված

@hy

2010年の論文

@ja

2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

CYP2C9-CYP3A4 protein-protein interactions: role of the hydrophobic N terminus.

@ast

CYP2C9-CYP3A4 protein-protein interactions: role of the hydrophobic N terminus.

@en

type

label

CYP2C9-CYP3A4 protein-protein interactions: role of the hydrophobic N terminus.

@ast

CYP2C9-CYP3A4 protein-protein interactions: role of the hydrophobic N terminus.

@en

prefLabel

CYP2C9-CYP3A4 protein-protein interactions: role of the hydrophobic N terminus.

@ast

CYP2C9-CYP3A4 protein-protein interactions: role of the hydrophobic N terminus.

@en

P1433

Q33891038-7737A872-607F-434C-8AEC-37B070B9591F

P1476

Q33891038-9B0D457B-AC1F-45B7-A844-F9567A39FCB9

P2093

Q33891038-B30B008E-39C1-4E50-9C69-6A615FFB965F

Q33891038-B470CEAD-11D3-432F-8484-A6FFF9BDC8A5

Q33891038-D62567A9-1CAC-486A-A753-A0EF98C89F86

Q33891038-F121018B-516C-48C6-B47E-8392BBEC18F7

P2860

Q33891038-076B0802-8EDD-434C-A586-FCBD00270C8D

Q33891038-0F3AF8AB-9D69-482C-A6D7-E7040E80CB3E

Q33891038-16F704A3-2CFB-4F0C-B79A-C1D3508DC094

Q33891038-23EC87AA-A494-44DC-B72D-2CE55A39FD7D

Q33891038-31BA9E14-7DB1-438E-B440-87F16E4554F1

Q33891038-34BB0397-55F2-41C8-8053-1B92997758E7

Q33891038-4A3C2756-0F1E-4242-8EF7-283604D7B86C

Q33891038-4C25AF94-2E49-45EF-BA6A-5D46ACF01439

Q33891038-5FB50909-648D-4941-B429-F83CBEA3FEDD

Q33891038-6319A865-27F0-4570-96BB-6D0C6DBD4A54

P304

Q33891038-551823C0-B930-420A-95A9-30A06430A711

P31

Q33891038-5AB2AEF8-4FB9-4C56-B112-A05E0575EEE6

P356

Q33891038-1CA63190-B4B5-44FE-81DD-8BF52F791DFE

P433

Q33891038-D31409DD-D21A-4C78-B7ED-622BF1486A8D

P478

Q33891038-0BBDAD5A-F812-45DA-B4D0-F468C88FE35F

P577

Q33891038-CF71C645-4CCC-4865-BE16-F6BC1F988FD9

P5875

Q33891038-F61BAD26-98FD-4027-81B5-47C14C6F702A

P698

Q33891038-4024B6A6-5250-42E1-8289-CA251E3E3EE0

P921

Q33891038-B3E11E3F-ED73-4231-9525-5BAA81AE0717

P932

Q33891038-C5B30F82-0426-4256-A3DD-101C009B9C94

P356

P1433

Drug Metabolism and Disposition

P1476

CYP2C9-CYP3A4 protein-protein interactions: role of the hydrophobic N terminus.

@en

P2093

Harrison Tam

http://www.w3.org/2001/XMLSchema#string

Helen Zheng

http://www.w3.org/2001/XMLSchema#string

Murali Subramanian

http://www.w3.org/2001/XMLSchema#string

Timothy S Tracy

http://www.w3.org/2001/XMLSchema#string

P2860

Interactions of mammalian cytochrome P450, NADPH-cytochrome P450 reductase, and cytochrome b(5) enzymes

CYP2D6-CYP2C9 protein-protein interactions and isoform-selective effects on substrate binding and catalysis

Hepatic cytochrome P450 enzyme alterations in humans with progressive stages of nonalcoholic fatty liver disease

CYP2C9 protein interactions with cytochrome b(5): effects on the coupling of catalysis

Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians.

Rate-limiting steps in cytochrome P450 catalysis.

Organization of multiple cytochrome P450s with NADPH-cytochrome P450 reductase in membranes.

Effects of ionic strength on the functional interactions between CYP2B4 and CYP1A2.

Heteromeric complex formation between CYP2E1 and CYP1A2: evidence for the involvement of electrostatic interactions.

Cytochrome P450s and other enzymes in drug metabolism and toxicity.

P304

1003-1009

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1124/DMD.109.030155

http://www.w3.org/2001/XMLSchema#string

P433

6

http://www.w3.org/2001/XMLSchema#string

P478

38

http://www.w3.org/2001/XMLSchema#string

P577

2010-03-09T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

41848460

http://www.w3.org/2001/XMLSchema#string

P698

20215413

http://www.w3.org/2001/XMLSchema#string

P921

P932

2879957

http://www.w3.org/2001/XMLSchema#string