Microsomal monooxygenase as a multienzyme system: the role of P450-P450 interactions.
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A novel type of allosteric regulation: functional cooperativity in monomeric proteinsThe Role of Protein-Protein and Protein-Membrane Interactions on P450 FunctionRole of protein-protein interactions in cytochrome P450-mediated drug metabolism and toxicityInteractions among cytochromes P450 in microsomal membranes: oligomerization of cytochromes P450 3A4, 3A5, and 2E1 and its functional consequencesA large-scale allosteric transition in cytochrome P450 3A4 revealed by luminescence resonance energy transfer (LRET).Environmentally persistent free radical-containing particulate matter competitively inhibits metabolism by cytochrome P450 1A2.Mechanism of drug-drug interactions mediated by human cytochrome P450 CYP3A4 monomerImmobilized Cytochrome P450 for Monitoring of P450-P450 Interactions and MetabolismFunctional studies of N-terminally modified CYP2J2 epoxygenase in model lipid bilayersInteractions between cytochromes P450 2B4 (CYP2B4) and 1A2 (CYP1A2) lead to alterations in toluene disposition and P450 uncouplingCorrelating structure and function of drug-metabolizing enzymes: progress and ongoing challenges.Pivotal role of P450-P450 interactions in CYP3A4 allostery: the case of α-naphthoflavone.Physical Studies of P450-P450 Interactions: Predicting Quaternary Structures of P450 Complexes in Membranes from Their X-ray Crystal Structures.An overview of on-line systems using drug metabolizing enzymes integrated into capillary electrophoresis.The evolution of our understanding of endo-xenobiotic crosstalk and cytochrome P450 regulation and the therapeutic implications.Development of (18)F-labeled radiotracers for neuroreceptor imaging with positron emission tomographyThe functional effects of physical interactions involving cytochromes P450: putative mechanisms of action and the extent of these effects in biological membranes.Cytochrome P450 Organization and Function Are Modulated by Endoplasmic Reticulum Phospholipid Heterogeneity.Advances in the Understanding of Protein-Protein Interactions in Drug Metabolizing Enzymes through the Use of Biophysical Techniques.Liver microsomal lipid enhances the activity and redox coupling of colocalized cytochrome P450 reductase-cytochrome P450 3A4 in nanodiscs.Stochastic ensembles, conformationally adaptive teamwork, and enzymatic detoxification.Extensive protein interactions involving cytochrome P450 3A4: a possible contributor to the formation of a metabolosome.Confining a bi-enzyme inside the nanochannels of a porous aluminum oxide membrane for accelerating the enzymatic reactions.Characterization of interactions among CYP1A2, CYP2B4, and NADPH-cytochrome P450 reductase: Identification of specific protein complexes.Comparison of human cytochrome P450 1A1-catalysed oxidation of benzo[a]pyrene in prokaryotic and eukaryotic expression systems.Toward a systems approach to the human cytochrome P450 ensemble: interactions between CYP2D6 and CYP2E1 and their functional consequences.Drug-Drug Interactions between Atorvastatin and Dronedarone Mediated by Monomeric CYP3A4.NADPH-Cytochrome P450 Reductase Mediates the Resistance of () (Kirkaldy) to Abamectin
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Microsomal monooxygenase as a multienzyme system: the role of P450-P450 interactions.
description
article científic
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article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 12 March 2011
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vedecký článok
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vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
Microsomal monooxygenase as a multienzyme system: the role of P450-P450 interactions.
@en
Microsomal monooxygenase as a multienzyme system: the role of P450-P450 interactions.
@nl
type
label
Microsomal monooxygenase as a multienzyme system: the role of P450-P450 interactions.
@en
Microsomal monooxygenase as a multienzyme system: the role of P450-P450 interactions.
@nl
prefLabel
Microsomal monooxygenase as a multienzyme system: the role of P450-P450 interactions.
@en
Microsomal monooxygenase as a multienzyme system: the role of P450-P450 interactions.
@nl
P2860
P1476
Microsomal monooxygenase as a multienzyme system: the role of P450-P450 interactions
@en
P2093
Dmitri R Davydov
P2860
P304
P356
10.1517/17425255.2011.562194
P407
P577
2011-03-12T00:00:00Z