Sox2 promotes malignancy in glioblastoma by regulating plasticity and astrocytic differentiation - Wikidata - wikimedia - TriplyDB

Sox2 promotes malignancy in glioblastoma by regulating plasticity and astrocytic differentiation

Sox2 promotes malignancy in glioblastoma by regulating plasticity and astrocytic differentiation

http://www.wikidata.org/entity/Q33891224

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The mitotic kinesin KIF11 is a driver of invasion, proliferation, and self-renewal in glioblastoma.Targeting SOX2 as a Therapeutic Strategy in Glioblastoma RAD51 Is a Selective DNA Repair Target to Radiosensitize Glioma Stem Cells.NOS2 expression in glioma cell lines and glioma primary cell cultures: correlation with neurosphere generation and SOX-2 expression.MRI-localized biopsies reveal subtype-specific differences in molecular and cellular composition at the margins of glioblastoma.A CDC20-APC/SOX2 Signaling Axis Regulates Human Glioblastoma Stem-like Cells.Development of a Sox2 reporter system modeling cellular heterogeneity in glioma.Glioblastoma stem cells (GSCs) epigenetic plasticity and interconversion between differentiated non-GSCs and GSCs.Comparative transcriptomics reveals similarities and differences between astrocytoma grades.Inhibition of Fatty Acid Synthase Decreases Expression of Stemness Markers in Glioma Stem Cells.Microarray Expression Data Identify DCC as a Candidate Gene for Early Meningioma Progression Glioma Cells in the Tumor Periphery Have a Stem Cell Phenotype Loss of CX3CR1 increases accumulation of inflammatory monocytes and promotes gliomagenesis.Roles of sex-determining region Y-box 2 in cell pluripotency and tumor-related signaling pathways.RTVP-1 promotes mesenchymal transformation of glioma via a STAT-3/IL-6-dependent positive feedback loop.Effective treatment of glioblastoma requires crossing the blood-brain barrier and targeting tumors including cancer stem cells: The promise of nanomedicine Oxidative stress induces the acquisition of cancer stem-like phenotype in breast cancer detectable by using a Sox2 regulatory region-2 (SRR2) reporter Dysregulated miR-671-5p / CDR1-AS / CDR1 / VSNL1 axis is involved in glioblastoma multiforme.Isorhapontigenin suppresses growth of patient-derived glioblastoma spheres through regulating miR-145/SOX2/cyclin D1 axis.Cancer stem-like cells can be induced through dedifferentiation under hypoxic conditions in glioma, hepatoma and lung cancer.DICER governs characteristics of glioma stem cells and the resulting tumors in xenograft mouse models of glioblastoma Astrocyte-specific overexpressed gene signatures in response to methamphetamine exposure in vitro.SOX2 immunity and tissue resident memory in children and young adults with glioma.Significance of low mTORC1 activity in defining the characteristics of brain tumor stem cells.Optimization of Glioblastoma Mouse Orthotopic Xenograft Models for Translational Research.Sox2: regulation of expression and contribution to brain tumors.Brain Cancer Stem Cells in Adults and Children: Cell Biology and Therapeutic Implications.Perfused Three-dimensional Organotypic Culture of Human Cancer Cells for Therapeutic Evaluation.MicroRNA‑21 promotes migration and invasion of glioma cells via activation of Sox2 and β‑catenin signaling.Fibroblast growth factor 13 regulates glioma cell invasion and is important for bevacizumab-induced glioma invasion.Expression and prognostic value of JAM-A in gliomas.Glioma CpG Island Methylator Phenotype (G-CIMP): Biological and Clinical Implications.Plasticity in Glioma Stem Cell Phenotype and Its Therapeutic Implication.Identification of Differentially Expressed Genes between Original Breast Cancer and Xenograft Using Machine Learning Algorithms.Fibronectin Promotes the Malignancy of Glioma Stem-Like Cells Via Modulation of Cell Adhesion, Differentiation, Proliferation and Chemoresistance.Meta-Analysis and Experimental Validation Identified FREM2 and SPRY1 as New Glioblastoma Marker Candidates.R-spodin2 enhances canonical Wnt signaling to maintain the stemness of glioblastoma cells Modulation of mitochondrial DNA copy number in a model of glioblastoma induces changes to DNA methylation and gene expression of the nuclear genome in tumours

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Sox2 promotes malignancy in glioblastoma by regulating plasticity and astrocytic differentiation

http://www.wikidata.org/entity/Q33891224

description

2014 nî lūn-bûn

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2014 թուականի Մարտին հրատարակուած գիտական յօդուած

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2014 թվականի մարտին հրատարակված գիտական հոդված

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年论文

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Sox2 promotes malignancy in gl ...... and astrocytic differentiation

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Sox2 promotes malignancy in gl ...... and astrocytic differentiation

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Sox2 promotes malignancy in gl ...... and astrocytic differentiation

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Sox2 promotes malignancy in gl ...... and astrocytic differentiation

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Sox2 promotes malignancy in gl ...... and astrocytic differentiation

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J.NEO.2014.03.006

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Sox2 promotes malignancy in gl ...... and astrocytic differentiation

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Andrea D Transou

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Craig P Webb

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David Cherba

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Laila M Poisson

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Laura A Hasselbach

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Nancy W Lemke

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Susan M Irtenkauf

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Tom Mikkelsen

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Xin Hong

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P2860

BAALC, the human member of a novel mammalian neuroectoderm gene lineage, is implicated in hematopoiesis and acute leukemia

Sox-2 is expressed by glial and progenitor cells and Pax-6 is expressed by neuroblasts in the human subventricular zone

Core transcriptional regulatory circuitry in human embryonic stem cells

Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1

The potential role of podoplanin in tumour invasion

Identification of a cancer stem cell in human brain tumors

Reprogramming of human somatic cells to pluripotency with defined factors

Isolation and characterization of tumorigenic, stem-like neural precursors from human glioblastoma

The somatic genomic landscape of glioblastoma

Ttyh1, a Ca(2+)-binding protein localized to the endoplasmic reticulum, is required for early embryonic development

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193-206, 206.e19-25

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10.1016/J.NEO.2014.03.006

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3

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16

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Ana C. deCarvalho

Artem Berezovsky

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2014-03-01T00:00:00Z

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261607756

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24726753

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4094829

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