Control of precursor maturation and disposal is an early regulative mechanism in the normal insulin production of pancreatic β-cells.
about
Insulin biosynthetic interaction network component, TMEM24, facilitates insulin reserve pool releaseSubstrate-favored lysosomal and proteasomal pathways participate in the normal balance control of insulin precursor maturation and disposal in β-cells.β-Cells with relative low HIMP1 overexpression levels in a transgenic mouse line enhance basal insulin production and hypoxia/hypoglycemia tolerance.Proinsulin atypical maturation and disposal induces extensive defects in mouse Ins2+/Akita β-cells.Proinsulin misfolding and endoplasmic reticulum stress during the development and progression of diabetes.Dominant protein interactions that influence the pathogenesis of conformational diseases.Impairment of pancreatic β-cell function by chronic intermittent hypoxiaMisfolded proinsulin in the endoplasmic reticulum during development of beta cell failure in diabetes.Inhibition of peptidyl-prolyl cis-trans isomerase B mediates cyclosporin A-induced apoptosis of islet β cells
P2860
Q28584801-D66C0EA7-8CF7-4CA6-9BFD-7BAB36A87AC5Q34079350-BC1EDA8E-6F1D-46A4-8ACB-81617F970E02Q34217750-3B109587-28E7-4C1A-AF7D-B153BF1DE959Q34235559-8B1B901A-CE23-4439-9EAA-BF824846ABEAQ35498877-63E67A87-5A5B-42B2-9160-61B96F3C1D14Q36966865-2B714B19-FA3F-4ADA-929D-575598353197Q37130353-B41B9264-EABE-409E-81A0-5B5D33B36B27Q48152192-20775E44-48CA-4904-9247-DAD759A156DAQ57787043-75711AD9-B2C4-468B-983D-D62A092E34DB
P2860
Control of precursor maturation and disposal is an early regulative mechanism in the normal insulin production of pancreatic β-cells.
description
2011 nî lūn-bûn
@nan
2011 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Control of precursor maturatio ...... duction of pancreatic β-cells.
@ast
Control of precursor maturatio ...... duction of pancreatic β-cells.
@en
type
label
Control of precursor maturatio ...... duction of pancreatic β-cells.
@ast
Control of precursor maturatio ...... duction of pancreatic β-cells.
@en
prefLabel
Control of precursor maturatio ...... duction of pancreatic β-cells.
@ast
Control of precursor maturatio ...... duction of pancreatic β-cells.
@en
P2093
P2860
P1433
P1476
Control of precursor maturatio ...... duction of pancreatic β-cells.
@en
P2093
Kwame Osei
Qingxin Yuan
Xiaoping Zhang
P2860
P304
P356
10.1371/JOURNAL.PONE.0019446
P407
P577
2011-04-29T00:00:00Z