Aptamer-functionalized lipid nanoparticles targeting osteoblasts as a novel RNA interference-based bone anabolic strategy. - Wikidata - wikimedia - TriplyDB

Aptamer-functionalized lipid nanoparticles targeting osteoblasts as a novel RNA interference-based bone anabolic strategy.

Aptamer-functionalized lipid nanoparticles targeting osteoblasts as a novel RNA interference-based bone anabolic strategy.

http://www.wikidata.org/entity/Q33901933

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Targeted Delivery Systems for Molecular Therapy in Skeletal Disorders Molecular Selection, Modification and Development of Therapeutic Oligonucleotide Aptamers Bone site-specific delivery of siRNA Skeletal stem cells and their contribution to skeletal fragility: senescence and rejuvenation Progress and Challenges in Developing Aptamer-Functionalized Targeted Drug Delivery Systems Nucleic Acid Aptamers: An Emerging Tool for Biotechnology and Biomedical Sensing Macropinocytosis Exploitation by Cancers and Cancer Therapeutics Aptamer-Drug Conjugates Screening of efficient siRNA carriers in a library of surface-engineered dendrimers New Bioengineering Breakthroughs and Enabling Tools in Regenerative Medicine MiR-497∼195 cluster regulates angiogenesis during coupling with osteogenesis by maintaining endothelial Notch and HIF-1α activity.Osteoclast-derived exosomal miR-214-3p inhibits osteoblastic bone formation Scoparone affects lipid metabolism in primary hepatocytes using lipidomics In Vivo siRNA Delivery Using JC Virus-like Particles Decreases the Expression of RANKL in Rats Lipid Nanoparticle Delivery of siRNA to Osteocytes Leads to Effective Silencing of SOST and Inhibition of Sclerostin In Vivo.Osteoclastic miR-214 targets TRAF3 to contribute to osteolytic bone metastasis of breast cancer.Human CD64-targeted non-viral siRNA delivery system for blood monocyte gene modulation.Increased PLEKHO1 within osteoblasts suppresses Smad-dependent BMP signaling to inhibit bone formation during aging.Aptamers as targeted therapeutics: current potential and challenges.Delivery of siRNAs to Dendritic Cells Using DEC205-Targeted Lipid Nanoparticles to Inhibit Immune Responses.A Highlight of Recent Advances in Aptamer Technology and Its Application.Recent advances in siRNA delivery.Development of Bone Targeting Drugs.Small Players Ruling the Hard Game: siRNA in Bone Regeneration.Local and targeted drug delivery for bone regeneration.NF-κB as a Therapeutic Target in Inflammatory-Associated Bone Diseases.Development of nanomaterials for bone-targeted drug delivery.TET3 Mediates Alterations in the Epigenetic Marker 5hmC and Akt pathway in Steroid-Associated Osteonecrosis.Bone and metal targeted polymeric nanoparticles (US20150125391 A1): a patent evaluation.Targeting osteoblastic casein kinase-2 interacting protein-1 to enhance Smad-dependent BMP signaling and reverse bone formation reduction in glucocorticoid-induced osteoporosis.Recent Advances in SELEX Technology and Aptamer Applications in Biomedicine.A water-soluble nucleolin aptamer-paclitaxel conjugate for tumor-specific targeting in ovarian cancer.Fracture-Targeted Delivery of β-Catenin Agonists via Peptide-Functionalized Nanoparticles Augments Fracture Healing.Multifunctional stimuli responsive polymer-gated iron and gold-embedded silica nano golf balls: Nanoshuttles for targeted on-demand theranostics.Multivalent Presentation of Peptide Targeting Groups Alters Polymer Biodistribution to Target Tissues.Construction of a PLGA based, targeted siRNA delivery system for treatment of osteoporosis.Osteoblast-targeted delivery of miR-33-5p attenuates osteopenia development induced by mechanical unloading in mice.A novel therapeutic strategy for cartilage diseases based on lipid nanoparticle-RNAi delivery system.Development of Controlled Drug Delivery Systems for Bone Fracture-Targeted Therapeutic Delivery: A Review.Histone demethylase LSD1 regulates bone mass by controlling WNT7B and BMP2 signaling in osteoblasts.

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Aptamer-functionalized lipid nanoparticles targeting osteoblasts as a novel RNA interference-based bone anabolic strategy.

http://www.wikidata.org/entity/Q33901933

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2015 nî lūn-bûn

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2015 թուականի Փետրուարին հրատարակուած գիտական յօդուած

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2015 թվականի փետրվարին հրատարակված գիտական հոդված

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2015年の論文

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2015年論文

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Nature Medicine

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Aptamer-functionalized lipid n ...... e-based bone anabolic strategy

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P2093

Aiping Lu

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Airong Qian

http://www.w3.org/2001/XMLSchema#string

Bao-Ting Zhang

http://www.w3.org/2001/XMLSchema#string

Changwei Lu

http://www.w3.org/2001/XMLSchema#string

Chao Liang

http://www.w3.org/2001/XMLSchema#string

Cheng Lu

http://www.w3.org/2001/XMLSchema#string

Cheng Wang

http://www.w3.org/2001/XMLSchema#string

Defang Li

http://www.w3.org/2001/XMLSchema#string

Fuchu He

http://www.w3.org/2001/XMLSchema#string

Ge Zhang

http://www.w3.org/2001/XMLSchema#string

P2860

Human primary osteoclasts: in vitro generation and applications as pharmacological and clinical assay

Targeting WW domains linker of HECT-type ubiquitin ligase Smurf1 for activation by CKIP-1

Dynamin 2 mediates fluid-phase micropinocytosis in epithelial cells

Development of DNA aptamers using Cell-SELEX.

miR-214 targets ATF4 to inhibit bone formation.

Rational truncation of an RNA aptamer to prostate-specific membrane antigen using computational structural modeling.

RNA therapeutics targeting osteoclast-mediated excessive bone resorption.

Generating aptamers by cell-SELEX for applications in molecular medicine

Bone-targeting macromolecular therapeutics.

Liposomal, nanoparticle, and conjugated formulations of anticancer agents.

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10.1038/NM.3791

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