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The Prodrug Approach: A Successful Tool for Improving Drug SolubilitySynthesis and biological evaluation of a new polymeric conjugate and nanocarrier with osteotropic propertiesExperiments and synthesis of bone-targeting epirubicin with the water-soluble macromolecular drug delivery systems of oxidized-dextran.Selectivity in bone targeting with multivalent dendritic polyanion dye conjugates.A novel biomaterial for osteotropic drug nanocarriers: synthesis and biocompatibility evaluation of a PLGA-ALE conjugate.Synthesis and preliminary evaluation in vitro of novel naproxen-dendritic peptide conjugates.Osteotropic therapy via targeted layer-by-layer nanoparticles.Aptamer-functionalized lipid nanoparticles targeting osteoblasts as a novel RNA interference-based bone anabolic strategy.Macromolecular therapeuticsModular 'click-in-emulsion' bone-targeted nanogels.Peptide Decoration of Nanovehicles to Achieve Active Targeting and Pathology-Responsive Cellular Uptake for Bone Metastasis Chemotherapy.Molecular Design of Bisphosphonate-Modified Proteins for Efficient Bone Targeting In Vivo.RNA therapeutics targeting osteoclast-mediated excessive bone resorption.Targeting polymer therapeutics to bone.Biodistribution and pharmacokinetic studies of bone-targeting N-(2-hydroxypropyl)methacrylamide copolymer-alendronate conjugates.Bone-crack detection, targeting, and repair using ion gradients.Drug delivery strategies for cathepsin inhibitors in joint diseases.POLYMERIC BIOMATERIALS AND NANOMEDICINES.Drug delivery strategies for common orofacial diseases.Efficiency of high molecular weight backbone degradable HPMA copolymer-prostaglandin E1 conjugate in promotion of bone formation in ovariectomized rats.Bone selective protective effect of a novel bone-seeking estrogen on trabecular bone in ovariectomized rats.Pamidronate functionalized nanoconjugates for targeted therapy of focal skeletal malignant osteolysis.Feasibility of using a bone-targeted, macromolecular delivery system coupled with prostaglandin E(1) to promote bone formation in aged, estrogen-deficient rats.Study of a new bone-targeting titanium implant-bone interface.Nanotechnology controlled drug delivery for treating bone diseases.Beyond oncology--application of HPMA copolymers in non-cancerous diseases.Polymer-drug conjugates for novel molecular targets.Bone-seeking probes for optical and magnetic resonance imaging.Treating metastatic cancer with nanotechnology.From nano- to macro-scale: nanotechnology approaches for spatially controlled delivery of bioactive factors for bone and cartilage engineering.Exploring drug delivery systems for treating osteoporosis.Bisphosphonates: therapeutics potential and recent advances in drug delivery.Role of polymer-drug conjugates in organ-specific delivery systems.Development of Bone Targeting Drugs.DOPA-based paclitaxel-loaded liposomes with modifications of transferrin and alendronate for bone and myeloma targeting.Advances in Controlled Drug Delivery for Treatment of OsteoporosisBisphosphonate-functionalized poly(β-amino ester) network polymers.Biodistribution of Fracture-Targeted GSK3β Inhibitor-Loaded Micelles for Improved Fracture Healing.Bone and metal targeted polymeric nanoparticles (US20150125391 A1): a patent evaluation.Bisphosphonate-coated BSA nanoparticles lack bone targeting after systemic administration.
P2860
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P2860
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
Bone-targeting macromolecular therapeutics.
@ast
Bone-targeting macromolecular therapeutics.
@en
type
label
Bone-targeting macromolecular therapeutics.
@ast
Bone-targeting macromolecular therapeutics.
@en
prefLabel
Bone-targeting macromolecular therapeutics.
@ast
Bone-targeting macromolecular therapeutics.
@en
P2093
P1476
Bone-targeting macromolecular therapeutics
@en
P2093
Jindrich Kopecek
Pavla Kopecková
P304
P356
10.1016/J.ADDR.2004.12.011
P407
P577
2005-04-15T00:00:00Z