Structure of Mycobacterium tuberculosis glutamine synthetase in complex with a transition-state mimic provides functional insights.
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Complexed Structures of Formylglycinamide Ribonucleotide Amidotransferase from Thermotoga maritima Describe a Novel ATP Binding Protein Superfamily † , ‡Lengsin Is a Survivor of an Ancient Family of Class I Glutamine Synthetases Re-engineered by Evolution for a Role in the Vertebrate LensStructural Basis for Feedback and Pharmacological Inhibition of Saccharomyces cerevisiae Glutamate Cysteine LigaseTrisubstituted Imidazoles as Mycobacterium tuberculosis Glutamine Synthetase InhibitorsStructures of the Bacillus subtilis Glutamine Synthetase Dodecamer Reveal Large Intersubunit Catalytic Conformational Changes Linked to a Unique Feedback Inhibition MechanismFunctional roles of the conserved Glu304 loop of Bacillus subtilis glutamine synthetaseInhibition of human glutamine synthetase by L-methionine-S,R-sulfoximine-relevance to the treatment of neurological diseases.Feedback-resistant mutations in Bacillus subtilis glutamine synthetase are clustered in the active site.Glutamine Synthetase Drugability beyond Its Active Site: Exploring Oligomerization Interfaces and Pockets.Identification of the enzyme responsible for N-acetylation of norfloxacin by Microbacterium sp. Strain 4N2-2.Novel trans-Acting Bacillus subtilis glnA mutations that derepress glnRA expression.Advances In Mycobacterium Tuberculosis Therapeutics Discovery Utlizing Structural Biology.Inhibition of glutamine synthetase: a potential drug target in Mycobacterium tuberculosis.Production of recombinant proteins in Mycobacterium smegmatis for structural and functional studies.The Molecular Basis of TnrA Control by Glutamine Synthetase in Bacillus subtilis.Critical Evaluation of the Changes in Glutamine Synthetase Activity in Models of Cerebral Stroke.Cloning, molecular characterization, and phylogeny of two evolutionary distinct glutamine synthetase isoforms in the green microalga Haematococcus pluvialis (Chlorophyceae).Glutamine synthetase stabilizes the binding of GlnR to nitrogen fixation gene operators.Depupylase Dop Requires Inorganic Phosphate in the Active Site for Catalysis.Probing the origins of glutathione biosynthesis through biochemical analysis of glutamate-cysteine ligase and glutathione synthetase from a model photosynthetic prokaryote.A structural overview of mycobacterial adhesins: Key biomarkers for diagnostics and therapeutics.Reaction Mechanism of Mycobacterium Tuberculosis Glutamine Synthetase Using Quantum Mechanics/Molecular Mechanics Calculations.Chemoselective generation of acyl phosphates, acylium ion equivalents, from carboxylic acids and an organophosphate ester in the presence of a Brønsted acid.Characterization of an L-phosphinothricin resistant glutamine synthetase from Exiguobacterium sp. and its improvement.Electrophilic activation of aminocarboxylic acid by phosphate ester promotes Friedel-Crafts acylation by overcoming charge-charge repulsion.Atomic structure of plant glutamine synthetase: a key enzyme for plant productivity.Application of quantum mechanics/molecular mechanics methods in the study of enzymatic reaction mechanismsStructural Analysis of Glutamine Synthetase from Helicobacter pylori2D-QSAR, Docking Studies, and In Silico ADMET Prediction of Polyphenolic Acetates as Substrates for Protein Acetyltransferase Function of Glutamine Synthetase of Mycobacterium tuberculosis
P2860
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P2860
Structure of Mycobacterium tuberculosis glutamine synthetase in complex with a transition-state mimic provides functional insights.
description
2005 nî lūn-bûn
@nan
2005 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Structure of Mycobacterium tub ...... provides functional insights.
@ast
Structure of Mycobacterium tub ...... provides functional insights.
@en
type
label
Structure of Mycobacterium tub ...... provides functional insights.
@ast
Structure of Mycobacterium tub ...... provides functional insights.
@en
prefLabel
Structure of Mycobacterium tub ...... provides functional insights.
@ast
Structure of Mycobacterium tub ...... provides functional insights.
@en
P2093
P2860
P356
P1476
Structure of Mycobacterium tub ...... provides functional insights.
@en
P2093
Sherry L Mowbray
T Alwyn Jones
Wojciech W Krajewski
P2860
P304
10499-10504
P356
10.1073/PNAS.0502248102
P407
P577
2005-07-18T00:00:00Z