Identification of the function of gene lndM2 encoding a bifunctional oxygenase-reductase involved in the biosynthesis of the antitumor antibiotic landomycin E by Streptomyces globisporus 1912 supports the originally assigned structure for landomycin
about
Generation of new landomycins with altered saccharide patterns through over-expression of the glycosyltransferase gene lanGT3 in the biosynthetic gene cluster of landomycin A in Streptomyces cyanogenus S-136.On the acceptor substrate of C-glycosyltransferase UrdGT2: three prejadomycin C-Glycosides from an engineered mutant of Streptomyces globisporus 1912 DeltalndE(urdGT2).Cyclization of aromatic polyketides from bacteria and fungiEnzymatic total synthesis of rabelomycin, an angucycline group antibiotic.11-Deoxylandomycinone and landomycins X-Z, new cytotoxic angucyclin(on)es from a Streptomyces cyanogenus K62 mutant strain.Tailoring enzymes involved in the biosynthesis of angucyclines contain latent context-dependent catalytic activities.Cloning and Heterologous Expression of the Grecocycline Biosynthetic Gene Cluster.Type II polyketide synthases: gaining a deeper insight into enzymatic teamwork.Elucidation of oxygenation steps during oviedomycin biosynthesis and generation of derivatives with increased antitumor activity.Angucyclines: Biosynthesis, mode-of-action, new natural products, and synthesis.Delineation of gilvocarcin, jadomycin, and landomycin pathways through combinatorial biosynthetic enzymology.Cloning and characterization of a gene cluster for hatomarubigin biosynthesis in Streptomyces sp. strain 2238-SVT4Premithramycinone G, an early shunt product of the mithramycin biosynthetic pathway accumulated upon inactivation of oxygenase MtmOIIBioactive compounds from marine actinomycetes.Cooperation of two bifunctional enzymes in the biosynthesis and attachment of deoxysugars of the antitumor antibiotic mithramycin.LanV, a bifunctional enzyme: aromatase and ketoreductase during landomycin A biosynthesis.Generation of new compounds through unbalanced transcription of landomycin A cluster.Elucidation of post-PKS tailoring steps involved in landomycin biosynthesis.Nocardiopsistins A-C: New angucyclines with anti-MRSA activity isolated from a marine sponge-derived sp. HB-J378
P2860
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P2860
Identification of the function of gene lndM2 encoding a bifunctional oxygenase-reductase involved in the biosynthesis of the antitumor antibiotic landomycin E by Streptomyces globisporus 1912 supports the originally assigned structure for landomycin
description
2005 nî lūn-bûn
@nan
2005 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Identification of the function ...... igned structure for landomycin
@ast
Identification of the function ...... igned structure for landomycin
@en
type
label
Identification of the function ...... igned structure for landomycin
@ast
Identification of the function ...... igned structure for landomycin
@en
prefLabel
Identification of the function ...... igned structure for landomycin
@ast
Identification of the function ...... igned structure for landomycin
@en
P2093
P2860
P50
P356
P1476
Identification of the function ...... igned structure for landomycin
@en
P2093
Almuth Mayers
Andriy Luzhetskyy
Jose A Salas
Jürgen Rohr
Mohammad Nur-E-Alam
P2860
P304
P356
10.1021/JO0483623
P407
P577
2005-01-01T00:00:00Z