Tau mutations in frontotemporal dementia FTDP-17 and their relevance for Alzheimer's disease.
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Genetics of Progressive Supranuclear PalsyChanges in dendritic complexity and spine morphology in transgenic mice expressing human wild-type tau.Hyperphosphorylated tau in parahippocampal cortex impairs place learning in aged mice expressing wild-type human tauAggregation of detergent-insoluble tau is involved in neuronal loss but not in synaptic lossTherapeutic potential of resveratrol in Alzheimer's diseaseDifferent associational and conformational behaviors between the second and third repeat fragments in the tau microtubule-binding domain.Binding of copper (II) ion to an Alzheimer's tau peptide as revealed by MALDI-TOF MS, CD, and NMR.Tau is endogenously nitrated in mouse brain: identification of a tyrosine residue modified in vivo by NO.Physiological transgene regulation and functional complementation of a neurological disease gene deficiency in neuronsThe splice of life: alternative splicing and neurological disease.Interactions between amyloid-β and Tau fragments promote aberrant aggregates: implications for amyloid toxicityH1 haplotype of the MAPT gene is associated with lower regional gray matter volume in healthy carriers.Gene identification in Alzheimer's disease.A powerful yeast model to investigate the synergistic interaction of α-synuclein and tau in neurodegeneration.Deciphering the genesis and fate of amyloid beta-protein yields novel therapies for Alzheimer disease.Spectroscopic approaches to the conformation of tau protein in solution and in paired helical filaments.Remodeling of the conformational ensemble of the repeat domain of tau by an aggregation enhancer.Modeling Alzheimer's disease: from past to futureTau as a therapeutic target in neurodegenerative disease.Biochemical Distribution of Tau Protein in Synaptosomal Fraction of Transgenic Mice Expressing Human P301L Tau.Frontotemporal lobar degeneration: epidemiology, pathology, diagnosis and management.Behind the curtain of tauopathy: a show of multiple players orchestrating tau toxicity.Active c-jun N-terminal kinase induces caspase cleavage of tau and additional phosphorylation by GSK-3beta is required for tau aggregation.Rapid and efficient generation of oligodendrocytes from human induced pluripotent stem cells using transcription factors.Competing interactions stabilize pro- and anti-aggregant conformations of human Tau.Derailed intraneuronal signalling drives pathogenesis in sporadic and familial Alzheimer's disease.Possible role of each repeat structure of the microtubule-binding domain of the tau protein in in vitro aggregation.Insights into amyloid disease from fly models.Isoform-independent and -dependent phosphorylation of microtubule-associated protein tau in mouse brain during postnatal development.Amyloidogenesis of Tau protein.Four-repeat tauopathy clinically presenting as posterior cortical atrophy: atypical corticobasal degeneration?Kidins220 accumulates with tau in human Alzheimer's disease and related models: modulation of its calpain-processing by GSK3β/PP1 imbalance.Temporally distinct phosphorylations differentiate Tau-dependent learning deficits and premature mortality in Drosophila.The Tau Gene Haplotype H1 Confers a Susceptibility to Parkinson’s DiseaseTau Pathology in Parkinson's DiseaseSirt1 enhances tau exon 10 inclusion and improves spatial memory of Htau mice
P2860
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P2860
Tau mutations in frontotemporal dementia FTDP-17 and their relevance for Alzheimer's disease.
description
2000 nî lūn-bûn
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2000 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2000年の論文
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2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Tau mutations in frontotempora ...... vance for Alzheimer's disease.
@ast
Tau mutations in frontotempora ...... vance for Alzheimer's disease.
@en
type
label
Tau mutations in frontotempora ...... vance for Alzheimer's disease.
@ast
Tau mutations in frontotempora ...... vance for Alzheimer's disease.
@en
prefLabel
Tau mutations in frontotempora ...... vance for Alzheimer's disease.
@ast
Tau mutations in frontotempora ...... vance for Alzheimer's disease.
@en
P1476
Tau mutations in frontotempora ...... vance for Alzheimer's disease.
@en
P2093
M G Spillantini
P304
P356
10.1016/S0925-4439(00)00037-5
P407
P577
2000-07-01T00:00:00Z