Aggregation of detergent-insoluble tau is involved in neuronal loss but not in synaptic loss - Wikidata - wikimedia - TriplyDB

Aggregation of detergent-insoluble tau is involved in neuronal loss but not in synaptic loss

Aggregation of detergent-insoluble tau is involved in neuronal loss but not in synaptic loss

http://www.wikidata.org/entity/Q30497471

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Tau-Centric Targets and Drugs in Clinical Development for the Treatment of Alzheimer's Disease Intracellular Calcium Dysregulation: Implications for Alzheimer's Disease Neuropathological alterations in Alzheimer disease Toxic tau oligomer formation blocked by capping of cysteine residues with 1,2-dihydroxybenzene groups.Tau physiology and pathomechanisms in frontotemporal lobar degeneration Tau accumulation causes mitochondrial distribution deficits in neurons in a mouse model of tauopathy and in human Alzheimer's disease brain Microtubule-associated protein tau is essential for long-term depression in the hippocampus Long- and short-term CDK5 knockdown prevents spatial memory dysfunction and tau pathology of triple transgenic Alzheimer's mice SUMOylation at K340 inhibits tau degradation through deregulating its phosphorylation and ubiquitination.A powerful yeast model to investigate the synergistic interaction of α-synuclein and tau in neurodegeneration.Tau oligomers impair memory and induce synaptic and mitochondrial dysfunction in wild-type mice.The many faces of tau GSK-3β and memory formation Soluble forms of tau are toxic in Alzheimer's disease.HDAC6 mutations rescue human tau-induced microtubule defects in Drosophila.Synaptic alterations in the rTg4510 mouse model of tauopathy.Bexarotene targets autophagy and is protective against thromboembolic stroke in aged mice with tauopathy Neuronal life span versus health span: principles of natural selection at work in the degenerating brain.Epigenetic treatment of neurological disease.Mouse models of Alzheimer's disease.Immunotherapy for Alzheimer's disease: from anti-β-amyloid to tau-based immunization strategies.Tau-directed approaches for the treatment of Alzheimer's disease: focus on leuco-methylthioninium.Sex Impact on Tau-Aggregation and Postsynaptic Protein Levels in the P301L Mouse Model of Tauopathy.Synergistic influence of phosphorylation and metal ions on tau oligomer formation and coaggregation with α-synuclein at the single molecule level.Adaptive responses to alloxan-induced mild oxidative stress ameliorate certain tauopathy phenotypes.Comparative analysis of autophagy and tauopathy related markers in cerebral ischemia and Alzheimer's disease animal models.The Neurotoxic TAU45-230 Fragment Accumulates in Upper and Lower Motor Neurons in Amyotrophic Lateral Sclerosis Subjects.Tau in MAPK activation.Modification of Tau by 8-Nitroguanosine 3',5'-Cyclic Monophosphate (8-Nitro-cGMP): EFFECTS OF NITRIC OXIDE-LINKED CHEMICAL MODIFICATION ON TAU AGGREGATION.AMPA Receptor Trafficking in Natural and Pathological Aging.Reversibility of Tau-related cognitive defects in a regulatable FTD mouse model.Tau-based therapeutics for Alzheimer's disease: active and passive immunotherapy.

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P2860

Aggregation of detergent-insoluble tau is involved in neuronal loss but not in synaptic loss

http://www.wikidata.org/entity/Q30497471

description

2010 nî lūn-bûn

@nan

2010 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

@zh-hant

2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

Aggregation of detergent-insol ...... loss but not in synaptic loss

@ast

Aggregation of detergent-insol ...... loss but not in synaptic loss

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type

label

Aggregation of detergent-insol ...... loss but not in synaptic loss

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Aggregation of detergent-insol ...... loss but not in synaptic loss

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prefLabel

Aggregation of detergent-insol ...... loss but not in synaptic loss

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Aggregation of detergent-insol ...... loss but not in synaptic loss

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JBC.M110.136630

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Journal of Biological Chemistry

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Aggregation of detergent-insol ...... loss but not in synaptic loss

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P2093

Akihiko Takashima

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Boyoung Lee

http://www.w3.org/2001/XMLSchema#string

Miyuki Murayama

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Naruhiko Sahara

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Shunji Yamashita

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Sumihiro Maeda

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Tatsuya Mizoroki

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Tetsuya Fukuda

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Tetsuya Kimura

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Yuji Yoshiike

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P2860

Neuronal Cdc2-like protein kinase (Cdk5/p25) is associated with protein phosphatase 1 and phosphorylates inhibitor-2

GSK-3beta is required for memory reconsolidation in adult brain

Tau suppression in a neurodegenerative mouse model improves memory function

Hyperphosphorylated tau in parahippocampal cortex impairs place learning in aged mice expressing wild-type human tau

A preparation of Alzheimer paired helical filaments that displays distinct tau proteins by polyacrylamide gel electrophoresis.

Tau mutations in frontotemporal dementia FTDP-17 and their relevance for Alzheimer's disease.

Molecular genetics of chromosome 17 tauopathies.

Region-specific dissociation of neuronal loss and neurofibrillary pathology in a mouse model of tauopathy.

Transgenic animal models of Alzheimer's disease and related disorders: histopathology, behavior and therapy.

Mutations causing neurodegenerative tauopathies.

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38692-38699

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10.1074/JBC.M110.136630

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49

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285

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Ioannis Sotiropoulos

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2010-10-04T00:00:00Z

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20921222

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2992302

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