β2-Agonist induced cAMP is decreased in asthmatic airway smooth muscle due to increased PDE4D - Wikidata - wikimedia - TriplyDB

β2-Agonist induced cAMP is decreased in asthmatic airway smooth muscle due to increased PDE4D

β2-Agonist induced cAMP is decreased in asthmatic airway smooth muscle due to increased PDE4D

http://www.wikidata.org/entity/Q33911113

about

Airway hyperresponsiveness; smooth muscle as the principal actor Stereoselective activity of 2-(4-amino-3-chloro-5- trifluomethyl-phenyl)-2-tert-butylamino-ethanol hydrochloride to improve the pulmonary function in asthma.Bitter taste receptor function in asthmatic and nonasthmatic human airway smooth muscle cells.Targeting protein-protein interactions within the cyclic AMP signaling system as a therapeutic strategy for cardiovascular disease.Innate immune receptors in human airway smooth muscle cells: activation by TLR1/2, TLR3, TLR4, TLR7 and NOD1 agonists Constitutively active signaling by the G protein βγ-subunit mediates intrinsically increased phosphodiesterase-4 activity in human asthmatic airway smooth muscle cells.Defective Resensitization in Human Airway Smooth Muscle Cells Evokes β-Adrenergic Receptor Dysfunction in Severe Asthma Extraction and elemental analysis of Coleus forskohlii extract G Protein βγ-subunit signaling mediates airway hyperresponsiveness and inflammation in allergic asthma.cAMP-mediated secretion of brain-derived neurotrophic factor in developing airway smooth muscle.Aberrant DNA Methylation of Phosphodiesterase [corrected] 4D Alters Airway Smooth Muscle Cell Phenotypes.Inhibition of PI3K promotes dilation of human small airways in a rho kinase-dependent manner.Large-scale profiling of signalling pathways reveals an asthma specific signature in bronchial smooth muscle cells Epigenetic alterations by DNA methylation in house dust mite-induced airway hyperresponsiveness.Inhibition of phosphodiesterase 4 modulates cytokine induction from toll like receptor activated, but not rhinovirus infected, primary human airway smooth muscle.Active components of ginger potentiate β-agonist-induced relaxation of airway smooth muscle by modulating cytoskeletal regulatory proteins.Novel cAMP signalling paradigms: therapeutic implications for airway disease Targeting airway smooth muscle in airways diseases: an old concept with new twists Genetic basis for personalized medicine in asthma.Untangling asthma phenotypes and endotypes.cAMP regulation of airway smooth muscle function.PDE inhibitors currently in early clinical trials for the treatment of asthma.TLR2 activation causes tachyphylaxis to β2 -agonists in vitro and ex vivo: modelling bacterial exacerbation.RGS5 gene and therapeutic response to short acting bronchodilators in paediatric asthma patients.Thiazolidinediones inhibit airway smooth muscle release of the chemokine CXCL10: in vitro comparison with current asthma therapies.Phosphodiesterase 4 Inhibitors Attenuate the Asthma Phenotype Produced by β2-Adrenoceptor Agonists in Phenylethanolamine N-Methyltransferase-Knockout Mice Novel relaxant effects of RPL554 on guinea pig tracheal smooth muscle contractility.TGF-β1 Evokes Human Airway Smooth Muscle Cell Shortening and Hyperresponsiveness via Smad3.Inhibitors of Phosphodiesterase 4, but Not Phosphodiesterase 3, Increase β2-Agonist-Induced Expression of Antiinflammatory Mitogen-Activated Protein Kinase Phosphatase 1 in Airway Smooth Muscle Cells.Effect of Roflumilast on Airway Blood Flow in COPD: A Pilot Study.Epac Function and cAMP Scaffolds in the Heart and Lung.Compartmentalized cAMP responses to prostaglandin EP2 receptor activation in human airway smooth muscle cells.A pathophysiological role of PDE3 in allergic airway inflammation.PDK1/Akt/PDE4D axis identified as a target for asthma remedy synergistic with β2 AR agonists by a natural agent arctigenin.

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P2860

β2-Agonist induced cAMP is decreased in asthmatic airway smooth muscle due to increased PDE4D

http://www.wikidata.org/entity/Q33911113

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2011 nî lūn-bûn

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2011 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2011 թվականի մայիսին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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name

β2-Agonist induced cAMP is dec ...... muscle due to increased PDE4D

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β2-Agonist induced cAMP is dec ...... muscle due to increased PDE4D

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β2-Agonist induced cAMP is dec ...... muscle due to increased PDE4D

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β2-Agonist induced cAMP is dec ...... muscle due to increased PDE4D

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β2-Agonist induced cAMP is dec ...... muscle due to increased PDE4D

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Janette K Burgess

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Judith L Black

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Kyoko Niimi

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Lyn M Moir

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Qi Ge

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Stephen B Liggett

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P2860

Bitter taste receptors on airway smooth muscle bronchodilate by localized calcium signaling and reverse obstruction

Phosphodiesterase type 4 expression and anti-proliferative effects in human pulmonary artery smooth muscle cells.

The phosphodiesterase inhibitor, pentoxifylline, alters rat intestinal epithelial cell proliferation via changes in the expression of transforming growth factors

PDE4D plays a critical role in the control of airway smooth muscle contraction

In vitro responsiveness of human asthmatic bronchus to carbachol, histamine, beta-adrenoceptor agonists and theophylline.

Terbutaline-induced desensitization of human lymphocyte beta 2-adrenoceptors. Accelerated restoration of beta-adrenoceptor responsiveness by prednisone and ketotifen

Beta 2-adrenoceptor agonist-mediated inhibition of human airway smooth muscle cell proliferation: importance of the duration of beta 2-adrenoceptor stimulation.

Crosstalk between Gi and Gq/Gs pathways in airway smooth muscle regulates bronchial contractility and relaxation.

Bronchial smooth muscle remodeling involves calcium-dependent enhanced mitochondrial biogenesis in asthma

Diminished sarco/endoplasmic reticulum Ca2+ ATPase (SERCA) expression contributes to airway remodelling in bronchial asthma.

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21611147

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