Crosstalk between Gi and Gq/Gs pathways in airway smooth muscle regulates bronchial contractility and relaxation.
about
Bitter taste receptors on airway smooth muscle bronchodilate by localized calcium signaling and reverse obstructionThe pharmacological rationale for combining muscarinic receptor antagonists and β-adrenoceptor agonists in the treatment of airway and bladder diseaseA genome-wide association study of bronchodilator response in asthmaticsRegulator of G-protein signaling-5 inhibits bronchial smooth muscle contraction in severe asthma.Repeated bouts of moderate-intensity aerobic exercise reduce airway reactivity in a murine asthma model.β2-Agonist induced cAMP is decreased in asthmatic airway smooth muscle due to increased PDE4DLoss of regulator of G protein signaling 5 promotes airway hyperresponsiveness in the absence of allergic inflammation.Respiratory syncytial virus reverses airway hyperresponsiveness to methacholine in ovalbumin-sensitized miceTargeted transgenesis identifies Gαs as the bottleneck in β2-adrenergic receptor cell signaling and physiological function in airway smooth muscle.ARG1 is a novel bronchodilator response gene: screening and replication in four asthma cohortsRegulatory haplotypes in ARG1 are associated with altered bronchodilator response.Beta-agonist-associated reduction in RGS5 expression promotes airway smooth muscle hyper-responsiveness.Paradoxical attenuation of β2-AR function in airway smooth muscle by Gi-mediated counterregulation in transgenic mice overexpressing type 5 adenylyl cyclase.Gi-coupled γ-aminobutyric acid-B receptors cross-regulate phospholipase C and calcium in airway smooth muscle.G Protein βγ-subunit signaling mediates airway hyperresponsiveness and inflammation in allergic asthma.TAS2R activation promotes airway smooth muscle relaxation despite β(2)-adrenergic receptor tachyphylaxis.Activation of endogenous GABAA channels on airway smooth muscle potentiates isoproterenol-mediated relaxation.Regulation of heterotrimeric G protein signaling in airway smooth muscle.Cryopreserved Human Precision-Cut Lung Slices as a Bioassay for Live Tissue Banking. A Viability Study of Bronchodilation with Bitter-Taste Receptor AgonistsShared genetic variants between serum levels of high-density lipoprotein cholesterol and wheezing in a cohort of children from CyprusPRKCA: a positional candidate gene for body mass index and asthma.Heterotrimeric G-proteins interact directly with cytoskeletal components to modify microtubule-dependent cellular processesNew perspectives regarding β(2) -adrenoceptor ligands in the treatment of asthma.Bronchodilators, receptors and cross-talk: Together is better?Long acting muscarinic antagonists for the treatment of chronic obstructive pulmonary disease: a review of current and developing drugs.Coupling of Airway Smooth Muscle Bitter Taste Receptors to Intracellular Signaling and Relaxation Is via Gαi1,2,3.Air quality and temperature effects on exercise-induced bronchoconstriction.TLR3 activation stimulates cytokine secretion without altering agonist-induced human small airway contraction or relaxation.Loss of Gi G-Protein-Coupled Receptor Signaling in Osteoblasts Accelerates Bone Fracture Healing.Prolonged heterologous beta2-adrenoceptor desensitization promotes proasthmatic airway smooth muscle function via PKA/ERK1/2-mediated phosphodiesterase-4 induction.A live cell assay of GPCR coupling allows identification of optogenetic tools for controlling Go and Gi signaling.Modulation of airway hyperresponsiveness by rhinovirus exposure
P2860
Q22337231-F3B2988E-4A4A-4C3E-A920-D34BCAB9E888Q26864937-17AEC054-60B7-4260-9D69-2C18E97A073DQ28943426-33F773E9-212E-41EB-B549-74A245806572Q30517755-25DA25F1-DA4E-4D26-A990-C381EAA3FAA0Q33658845-F455D015-258C-442B-9152-ECF444DA8059Q33911113-82E89158-C403-44CD-978D-590E6DBEFFC3Q33993700-3F010B79-0BEF-492F-B1A7-C6F5297F9D4EQ34441814-4ABC4B3F-E39D-4149-86EB-1B7245204E79Q34519352-ED3A031F-FE03-4681-A7B3-103317CAEC23Q34656675-84E5A0A5-F3A1-45F2-8405-4A14EE8C5D4EQ34665101-D64C512C-B620-4110-BB2A-DC135CFD2A06Q34719688-9AE7933B-7C37-4C19-B62A-51445744C008Q34720210-B011526F-2304-416C-B858-9194A78D4F30Q35684815-66AF878C-84C8-435A-B7B8-84AD42D0D428Q35772192-7D6B2DF6-21DC-4A56-86E4-E876D7A1F534Q36178070-402782F1-0FB3-4EB7-8C2B-98A5DB986AC5Q37018271-B50BD510-68D2-46C3-8C75-831D56D9BB38Q37038052-88126D3A-1AFC-465A-A0E9-F32454CECEF1Q37088236-B9D409CF-57F2-454C-941D-CA78DAEB0F77Q37093993-3A9373C4-0CBC-431C-9DCD-B203362A3714Q37253416-0D14E42C-ECC1-432E-BD5E-31328BB6C6F2Q37391238-497F8473-5FFC-482C-AC8E-F98217DF9A4EQ37822833-059D42ED-5810-4E3E-9C41-405DECE65D60Q38570698-4D2406E4-A043-4941-BB5B-F9020B28867EQ38779411-32AF36CD-ABB6-4257-8FD0-308C39671C56Q38987293-61AD00D0-709B-406D-8137-74897679825EQ40272925-97C0B601-412C-4BD1-954D-AEED449430AAQ45960709-EA6CF96D-17C5-4C86-B055-04024C487D1DQ46374125-9A864435-997B-44FD-A22F-BA09EF28F0C1Q46687772-BE6B015B-B34A-4CBF-8781-CE26ACA71864Q49196113-B0ED4D77-9974-4748-AA58-78D3C3E06F5AQ58107067-D7D67B90-F89A-4F55-A33A-F8AD9C815E46
P2860
Crosstalk between Gi and Gq/Gs pathways in airway smooth muscle regulates bronchial contractility and relaxation.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Crosstalk between Gi and Gq/Gs ...... contractility and relaxation.
@ast
Crosstalk between Gi and Gq/Gs ...... contractility and relaxation.
@en
type
label
Crosstalk between Gi and Gq/Gs ...... contractility and relaxation.
@ast
Crosstalk between Gi and Gq/Gs ...... contractility and relaxation.
@en
prefLabel
Crosstalk between Gi and Gq/Gs ...... contractility and relaxation.
@ast
Crosstalk between Gi and Gq/Gs ...... contractility and relaxation.
@en
P2093
P2860
P356
P1476
Crosstalk between Gi and Gq/Gs ...... contractility and relaxation.
@en
P2093
Clare B Glinka
Dennis W McGraw
Jean M Elwing
Kathryn A Mihlbachler
Kevin M Fogel
Marc E Rothenberg
Stephen B Liggett
Wayne C H Wang
P2860
P304
P356
10.1172/JCI30489
P407
P577
2007-04-05T00:00:00Z