ERK phosphorylates p66shcA on Ser36 and subsequently regulates p27kip1 expression via the Akt-FOXO3a pathway: implication of p27kip1 in cell response to oxidative stress.
about
Mammalian sterile 20-like kinase 3 (MST3) mediates oxidative-stress-induced cell death by modulating JNK activationSomething old, something new, something borrowed; how the thermoacidophilic archaeon Sulfolobus solfataricus responds to oxidative stressChemically diverse toxicants converge on Fyn and c-Cbl to disrupt precursor cell function.The oxidative stress adaptor p66Shc is required for permanent embryo arrest in vitro.SOD3 decreases ischemic injury derived apoptosis through phosphorylation of Erk1/2, Akt, and FoxO3a.Smoking p66Shc knocked out mice develop respiratory bronchiolitis with fibrosis but not emphysemaHIV gene expression deactivates redox-sensitive stress response program in mouse tubular cells both in vitro and in vivo.Pigment epithelium-derived factor inhibits neointimal hyperplasia after vascular injury by blocking NADPH oxidase-mediated reactive oxygen species generation.ShcA Protects against Epithelial-Mesenchymal Transition through Compartmentalized Inhibition of TGF-β-Induced Smad Activation.Novel role of p66Shc in ROS-dependent VEGF signaling and angiogenesis in endothelial cellsEndothelin-1 couples betaPix to p66Shc: role of betaPix in cell proliferation through FOXO3a phosphorylation and p27kip1 down-regulation independently of AktRegulation of Akt/FOXO3a/GSK-3beta/AR signaling network by isoflavone in prostate cancer cellsFOXO3a inhibits TNF-α- and IL-1β-induced astrocyte proliferation:Implication for reactive astrogliosisInhibition of p66ShcA longevity gene rescues podocytes from HIV-1-induced oxidative stress and apoptosisArginase-II induces vascular smooth muscle cell senescence and apoptosis through p66Shc and p53 independently of its l-arginine ureahydrolase activity: implications for atherosclerotic plaque vulnerabilityEndothelin-1 induces p66Shc activation through EGF receptor transactivation: Role of beta(1)Pix/Galpha(i3) interaction.Applications of post-translational modifications of FoxO family proteins in biological functions.The Role of p66shc in Oxidative Stress and Apoptosis.Oxidative stress, a common molecular pathway for kidney disease: role of the redox enzyme p66Shc.Modelling the p53/p66Shc Aging Pathway in the Shortest Living Vertebrate Nothobranchius Furzeri.Parathyroid Hormone-Related Protein Protects Osteoblastic Cells From Oxidative Stress by Activation of MKP1 Phosphatase.Effects of Resveratrol on p66Shc phosphorylation in cultured prostate cells.Anthocyanins Protect SK-N-SH Cells Against Acrolein-Induced Toxicity by Preserving the Cellular Redox State.Salicin, an extract from white willow bark, inhibits angiogenesis by blocking the ROS-ERK pathways.SHetA2 interference with mortalin binding to p66shc and p53 identified using drug-conjugated magnetic microspheresThe anti-angiogenic activities of glycyrrhizic acid in tumor progression.Phosphorylation of p66shc mediates 6-hydroxydopamine cytotoxicity.High Erk activity suppresses expression of the cell cycle inhibitor p27Kip1 in colorectal cancer cellsp66shc inhibits pro-survival epidermal growth factor receptor/ERK signaling during severe oxidative stress in mouse renal proximal tubule cells.AGE-receptor-1 counteracts cellular oxidant stress induced by AGEs via negative regulation of p66shc-dependent FKHRL1 phosphorylation.Regulation of FOXO3a/beta-catenin/GSK-3beta signaling by 3,3'-diindolylmethane contributes to inhibition of cell proliferation and induction of apoptosis in prostate cancer cells.Synaptic activity and nuclear calcium signaling protect hippocampal neurons from death signal-associated nuclear translocation of FoxO3a induced by extrasynaptic N-methyl-D-aspartate receptorsThe effect of nutritionally induced hyperlipidaemia on in vitro bovine embryo quality.The p66(Shc) redox adaptor protein is induced by saturated fatty acids and mediates lipotoxicity-induced apoptosis in pancreatic beta cells.A Rationale for Targeting Extracellular Regulated Kinases ERK1 and ERK2 in Glioblastoma.Mitochondria-associated membranes in aging and senescence: structure, function, and dynamics.Mechanisms in cardiac fibroblast growth: an obligate role for Skp2 and FOXO3a in ERK1/2 MAPK-dependent regulation of p27kip1.
P2860
Q24314652-C7466868-ACF7-4B58-A13F-CE95681214AAQ28476165-FE889D65-D5F3-4884-86C5-90906DDE1632Q33273613-E191C7E2-0EF2-47CC-839C-194B9288F079Q33307804-8DB935DD-7380-4472-ABC5-C4A3051B9638Q34016493-A8E04B3E-0967-46D9-B418-AA0629E140B0Q35581517-116E1392-7A86-47B5-9ADC-84CB75C4EDB7Q35652110-ABD24FF5-1EF7-490C-8F55-358916B3978BQ35855635-7921357C-F6F4-4246-BCCE-4166AC888AD1Q35872442-0893B84C-F73D-4B95-81C9-F84DC908F28BQ35964916-8359531D-300F-4A50-9C76-C65433FEB002Q36678087-ED54B047-F49A-4C6E-A35A-0F56445058FAQ36924212-042CA115-67E8-4CE6-971E-3913A7F2028EQ37106118-0F8F1EFD-1F7F-429A-BC07-13805F420D71Q37269247-A3BE8634-1F43-4E88-BC07-9ECCC20F1AB7Q37310506-DDD5BA46-835F-47AC-B1EE-BC4454A9EEB4Q37457148-213C22BB-2C3E-40F5-8C01-107CBBA0873AQ37888960-E4F5DD0F-EEB2-459B-985A-6D3DA29929AAQ38014850-130EDFCB-8AA3-41E2-B688-988F503DDC86Q38158050-0B7D2651-9D3C-412D-8CBB-3B356BDB20E8Q38395524-C6101353-9282-4DCA-B28B-DC563504AEE4Q38760873-26ACF742-2F4C-4D5B-A6AD-429DFB542991Q38780934-67284215-0C14-4DB6-B8EE-5AE5FDAF88CCQ38793119-9F1986F2-2599-4500-9A1D-143FFBCB2DA5Q39023080-C74D3E22-5287-42C8-8E78-EEFEF9EBB150Q39061148-7E72DC8D-9FDF-4F10-BE4A-2F324BAFB7EAQ39296184-4D536174-D788-49B3-AF59-50AD22DCC1D1Q39636299-D3183A29-7A13-4CE9-85DC-CD17321F247FQ39735717-EE7255FC-08FF-41D1-B81F-376FE8792A90Q40028539-2257D8FF-F5BD-47CE-81A1-41B8DDFB93C8Q40046348-A79CE229-CA40-474F-91FE-9CC42C7D8847Q40128741-108F60B2-7D26-4E6F-A714-90C0EF213718Q41048494-BDB3379C-8E26-4BD7-8977-AFB56BF37E68Q41609724-407CEB54-5361-484B-840B-AE1C41D280D1Q42152595-3CD8B212-F8F6-49A0-9928-C021F5C09458Q47784163-1C59856D-4DDD-45BF-9296-2279183752EEQ51737103-86588E53-2465-464F-87E9-8E6D61A8C829Q53071967-7E004AC5-DF7A-466C-890D-292A43664B23
P2860
ERK phosphorylates p66shcA on Ser36 and subsequently regulates p27kip1 expression via the Akt-FOXO3a pathway: implication of p27kip1 in cell response to oxidative stress.
description
2005 nî lūn-bûn
@nan
2005 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
ERK phosphorylates p66shcA on ...... response to oxidative stress.
@ast
ERK phosphorylates p66shcA on ...... response to oxidative stress.
@en
type
label
ERK phosphorylates p66shcA on ...... response to oxidative stress.
@ast
ERK phosphorylates p66shcA on ...... response to oxidative stress.
@en
prefLabel
ERK phosphorylates p66shcA on ...... response to oxidative stress.
@ast
ERK phosphorylates p66shcA on ...... response to oxidative stress.
@en
P2093
P2860
P356
P1476
ERK phosphorylates p66shcA on ...... response to oxidative stress.
@en
P2093
Eduardo J Firpo
Kanaga Sabapathy
Stephen P Goff
Xueying Wang
P2860
P304
P356
10.1091/MBC.E05-04-0301
P577
2005-06-01T00:00:00Z