Synaptic activity and nuclear calcium signaling protect hippocampal neurons from death signal-associated nuclear translocation of FoxO3a induced by extrasynaptic N-methyl-D-aspartate receptors
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Dysfunction of NMDA receptors in Alzheimer's diseaseRole of NMDA Receptor-Mediated Glutamatergic Signaling in Chronic and Acute NeuropathologiesMitochondrial localization of the forkhead box class O transcription factor FOXO3a in brainAlteration in basal and depolarization induced transcriptional network in iPSC derived neurons from Timothy syndrome.Synaptic versus extrasynaptic NMDA receptor signalling: implications for neurodegenerative disorders.Calcium signaling in synapse-to-nucleus communicationIncreasing levels of wild-type CREB up-regulates several activity-regulated inhibitor of death (AID) genes and promotes neuronal survival.Molecular pathway reconstruction and analysis of disturbed gene expression in depressed individuals who died by suicideSynaptic Activity Drives a Genomic Program That Promotes a Neuronal Warburg Effect.Forkhead transcription factor FOXO3a levels are increased in Huntington disease because of overactivated positive autofeedback loop.Mechanisms of specificity in neuronal activity-regulated gene transcriptionThe role of the tripartite glutamatergic synapse in the pathophysiology of Alzheimer's disease.Extrasynaptic N-methyl-D-aspartate (NMDA) receptor stimulation induces cytoplasmic translocation of the CDKL5 kinase and its proteasomal degradation.Synaptic NMDA receptors mediate hypoxic excitotoxic deathThe subtype of GluN2 C-terminal domain determines the response to excitotoxic insults.IL-1RAcPb signaling regulates adaptive mechanisms in neurons that promote their long-term survival following excitotoxic insults.Recovery of NMDA receptor currents from MK-801 blockade is accelerated by Mg2+ and memantine under conditions of agonist exposureThe influence of synaptic activity on neuronal health.Oligodendrocyte N-methyl-D-aspartate receptor signaling: insights into its functions.Neuronal calcium signaling: function and dysfunction.Calorie restriction and stroke.The nuclear calcium signaling target, activating transcription factor 3 (ATF3), protects against dendrotoxicity and facilitates the recovery of synaptic transmission after an excitotoxic insult.Therapeutic targeting of the pathological triad of extrasynaptic NMDA receptor signaling in neurodegenerations.Calmodulin kinase IV-dependent CREB activation is required for neuroprotection via NMDA receptor-PSD95 disruption.Neuroprotective effects of phenolic antioxidant tBHQ associate with inhibition of FoxO3a nuclear translocation and activityNMDA receptor signaling: death or survival?Nuclear calcium signaling induces expression of the synaptic organizers Lrrtm1 and Lrrtm2Mitochondrial calcium uniporter Mcu controls excitotoxicity and is transcriptionally repressed by neuroprotective nuclear calcium signals.The expression of insulin-like growth factor-1 in senior patients with diabetes and dementia.Mechanistic target of rapamycin complex 1 and 2 in human temporal lobe epilepsy.Cyclin D1 induction preceding neuronal death via the excitotoxic NMDA pathway involves selective stimulation of extrasynaptic NMDA receptors and JNK pathway.
P2860
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P2860
Synaptic activity and nuclear calcium signaling protect hippocampal neurons from death signal-associated nuclear translocation of FoxO3a induced by extrasynaptic N-methyl-D-aspartate receptors
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
Synaptic activity and nuclear ...... N-methyl-D-aspartate receptors
@en
type
label
Synaptic activity and nuclear ...... N-methyl-D-aspartate receptors
@en
prefLabel
Synaptic activity and nuclear ...... N-methyl-D-aspartate receptors
@en
P2860
P356
P1476
Synaptic activity and nuclear ...... N-methyl-D-aspartate receptors
@en
P2093
Hilmar Bading
Oliver Dick
P2860
P304
19354-19361
P356
10.1074/JBC.M110.127654
P407
P577
2010-04-19T00:00:00Z