Identification of an essential molecular contact point on the duck hepatitis B virus reverse transcriptase
about
Hepatitis B virus replicationHepatitis B virus reverse transcriptase: diverse functions as classical and emerging targets for antiviral interventionSubstrate specificity of the herpes simplex virus type 2 UL13 protein kinase.Sequences in the terminal protein and reverse transcriptase domains of the hepatitis B virus polymerase contribute to RNA binding and encapsidationEvidence for multiple distinct interactions between hepatitis B virus P protein and its cognate RNA encapsidation signal during initiation of reverse transcription.Combining genetic and biochemical approaches to identify functional molecular contact points.Hepadnavirus Genome Replication and Persistence.TP-RT domain interactions of duck hepatitis B virus reverse transcriptase in cis and in trans during protein-primed initiation of DNA synthesis in vitro.Carbonyl J acid derivatives block protein priming of hepadnaviral P protein and DNA-dependent DNA synthesis activity of hepadnaviral nucleocapsids.Hepatitis B Virus Polymerase Localizes to the Mitochondria, and Its Terminal Protein Domain Contains the Mitochondrial Targeting Signal.Comparative analysis of hepatitis B virus polymerase sequences required for viral RNA binding, RNA packaging, and protein priming.Chaperones activate hepadnavirus reverse transcriptase by transiently exposing a C-proximal region in the terminal protein domain that contributes to epsilon RNA bindingThe duck hepatitis B virus reverse transcriptase functions as a full-length monomer.Mapping of Functional Subdomains in the Terminal Protein Domain of Hepatitis B Virus Polymerase.A Tyr residue in the reverse transcriptase domain can mimic the protein-priming Tyr residue in the terminal protein domain of a hepadnavirus P proteinChaperone activation of the hepadnaviral reverse transcriptase for template RNA binding is established by the Hsp70 and stimulated by the Hsp90 system.An interdomain RNA binding site on the hepadnaviral polymerase that is essential for reverse transcriptionHydrophobic residues of terminal protein domain of hepatitis B virus polymerase contribute to distinct steps in viral genome replication.
P2860
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P2860
Identification of an essential molecular contact point on the duck hepatitis B virus reverse transcriptase
description
2005 nî lūn-bûn
@nan
2005 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Identification of an essential ...... B virus reverse transcriptase
@ast
Identification of an essential ...... B virus reverse transcriptase
@en
type
label
Identification of an essential ...... B virus reverse transcriptase
@ast
Identification of an essential ...... B virus reverse transcriptase
@en
prefLabel
Identification of an essential ...... B virus reverse transcriptase
@ast
Identification of an essential ...... B virus reverse transcriptase
@en
P2093
P2860
P1433
P1476
Identification of an essential ...... B virus reverse transcriptase
@en
P2093
Babatunde Adeyemo
John E Tavis
Lisa M Metzger
Matthew P Badtke
Yunhao Gong
P2860
P304
10164-10170
P356
10.1128/JVI.79.16.10164-10170.2005
P407
P577
2005-08-01T00:00:00Z