Multi-compound polarization by DNP allows simultaneous assessment of multiple enzymatic activities in vivo - Wikidata - wikimedia - TriplyDB

Multi-compound polarization by DNP allows simultaneous assessment of multiple enzymatic activities in vivo

Multi-compound polarization by DNP allows simultaneous assessment of multiple enzymatic activities in vivo

http://www.wikidata.org/entity/Q33913684

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Stable isotope-resolved metabolomics and applications for drug development Potential Clinical Roles for Metabolic Imaging with Hyperpolarized [1-(13)C]Pyruvate Chemistry and biochemistry of 13C hyperpolarized magnetic resonance using dynamic nuclear polarization Application of Good's buffers to pH imaging using hyperpolarized (13)C MRI Hyperpolarization MRI: Preclinical Models and Potential Applications in Neuroradiology.Kinetic analysis of hyperpolarized data with minimum a priori knowledge: Hybrid maximum entropy and nonlinear least squares method (MEM/NLS).MR Molecular Imaging of Brain Cancer Metabolism Using Hyperpolarized 13C Magnetic Resonance Spectroscopy.Imaging of pH in vivo using hyperpolarized 13C-labelled zymonic acid DNP by thermal mixing under optimized conditions yields >60,000-fold enhancement of 89Y NMR signal.Synthesis and testing of a p-H2 hyperpolarized 13C probe based on the pyrazolo[1,5-a]pyrimidineacetamide DPA-713, an MRI vector to target the peripheral benzodiazepine receptors.Probing early tumor response to radiation therapy using hyperpolarized [1-¹³C]pyruvate in MDA-MB-231 xenografts.A hydrogen peroxide-responsive hyperpolarized 13C MRI contrast agent.Hyperpolarized 13C MR for molecular imaging of prostate cancer.Hyperpolarized magnetic resonance: a novel technique for the in vivo assessment of cardiovascular disease.High-field small animal magnetic resonance oncology studies.Hyperpolarized 13C dehydroascorbate as an endogenous redox sensor for in vivo metabolic imaging Impact of Gd3+ on DNP of [1-13C]pyruvate doped with trityl OX063, BDPA, or 4-oxo-TEMPO.(13)C-labeled biochemical probes for the study of cancer metabolism with dynamic nuclear polarization-enhanced magnetic resonance imaging.Hyperpolarized 13C-pyruvate magnetic resonance reveals rapid lactate export in metastatic renal cell carcinomas Diffusion MR of hyperpolarized 13C molecules in solution.Generating contrast in hyperpolarized 13C MRI using ligand-receptor interactions.Frequency-specific SSFP for hyperpolarized ¹³C metabolic imaging at 14.1 T.Applications of NMR spectroscopy to systems biochemistry.Quantitative measurement of cancer metabolism using stimulated echo hyperpolarized carbon-13 MRS.Dynamic nuclear polarization of biocompatible (13)C-enriched carbonates for in vivo pH imaging Hyperpolarized NMR probes for biological assays.Current opportunities and challenges of magnetic resonance spectroscopy, positron emission tomography, and mass spectrometry imaging for mapping cancer metabolism in vivo.Metabolic reprogramming and validation of hyperpolarized 13C lactate as a prostate cancer biomarker using a human prostate tissue slice culture bioreactor Metabolic effects of signal transduction inhibition in cancer assessed by magnetic resonance spectroscopy.MRS and MRSI guidance in molecular medicine: targeting and monitoring of choline and glucose metabolism in cancer.Imaging pH with hyperpolarized 13C.Molecular characterization of rheumatoid arthritis with magnetic resonance imaging.Hyperpolarized (13)C-pyruvate magnetic resonance imaging in cancer diagnostics.A New Horizon of DNP technology: Application to In-vivo 13C Magnetic Resonance Spectroscopy and Imaging.Biochemical phosphates observed using hyperpolarized 31P in physiological aqueous solutions.Assessing Prostate Cancer Aggressiveness with Hyperpolarized Dual-Agent 3D Dynamic Imaging of Metabolism and Perfusion.T1 nuclear magnetic relaxation dispersion of hyperpolarized sodium and cesium hydrogencarbonate-13 C.Hyperpolarized 13C Metabolic Magnetic Resonance Spectroscopy and Imaging.Magnetic resonance imaging with hyperpolarized agents: methods and applications.Hyperpolarized NMR of plant and cancer cell extracts at natural abundance.

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P2860

Multi-compound polarization by DNP allows simultaneous assessment of multiple enzymatic activities in vivo

http://www.wikidata.org/entity/Q33913684

description

2010 nî lūn-bûn

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2010 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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2010 թվականի ապրիլին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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Multi-compound polarization by ...... e enzymatic activities in vivo

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Multi-compound polarization by ...... e enzymatic activities in vivo

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Multi-compound polarization by ...... e enzymatic activities in vivo

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J.JMR.2010.04.012

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Journal of Magnetic Resonance

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Multi-compound polarization by ...... e enzymatic activities in vivo

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P2093

Albert P Chen

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Daniel B Vigneron

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David M Wilson

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Jeffrey M Macdonald

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John Kurhanewicz

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Kayvan R Keshari

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Mark Van Criekinge

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Peder E Z Larson

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Robert Bok

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Sarah J Nelson

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P2860

Molecular imaging with endogenous substances

Increase in signal-to-noise ratio of > 10,000 times in liquid-state NMR

Why do cancers have high aerobic glycolysis?

Imaging of brain tissue pH and metabolites. A new approach for the validation of volume-selective NMR spectroscopy.

Combined magnetic resonance imaging and spectroscopic imaging approach to molecular imaging of prostate cancer.

Hyperpolarized 13C allows a direct measure of flux through a single enzyme-catalyzed step by NMR.

Production of hyperpolarized [1,4-13C2]malate from [1,4-13C2]fumarate is a marker of cell necrosis and treatment response in tumors.

Hyperpolarized [2-13C]-fructose: a hemiketal DNP substrate for in vivo metabolic imaging.

Hyperpolarized 13C lactate, pyruvate, and alanine: noninvasive biomarkers for prostate cancer detection and grading.

13C MR spectroscopy measurements of glutaminase activity in human hepatocellular carcinoma cells using hyperpolarized 13C-labeled glutamine.

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141-147

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scholarly article

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10.1016/J.JMR.2010.04.012

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1

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205

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2010-04-27T00:00:00Z

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44607757

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20478721

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2885774

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