Production of hyperpolarized [1,4-13C2]malate from [1,4-13C2]fumarate is a marker of cell necrosis and treatment response in tumors. - Wikidata - wikimedia - TriplyDB

Production of hyperpolarized [1,4-13C2]malate from [1,4-13C2]fumarate is a marker of cell necrosis and treatment response in tumors.

Production of hyperpolarized [1,4-13C2]malate from [1,4-13C2]fumarate is a marker of cell necrosis and treatment response in tumors.

http://www.wikidata.org/entity/Q37446412

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Potential Clinical Roles for Metabolic Imaging with Hyperpolarized [1-(13)C]Pyruvate Hyperpolarized (13)C Magnetic Resonance and Its Use in Metabolic Assessment of Cultured Cells and Perfused Organs Imaging radiation response in tumor and normal tissue.Biomarkers and molecular probes for cell death imaging and targeted therapeutics Hyperpolarized magnetic resonance as a sensitive detector of metabolic function Chemistry and biochemistry of 13C hyperpolarized magnetic resonance using dynamic nuclear polarization Clinical implications of cardiac hyperpolarized magnetic resonance imaging Imaging metabolic heterogeneity in cancer Preclinical assessment of carboplatin treatment efficacy in lung cancer by 18F-ICMT-11-positron emission tomography MR Imaging Biomarkers in Oncology Clinical Trials Hyperpolarization MRI: Preclinical Models and Potential Applications in Neuroradiology.Biomarkers in preclinical cancer imaging.Current and emerging quantitative magnetic resonance imaging methods for assessing and predicting the response of breast cancer to neoadjuvant therapy.Glutamate and glutamine: a review of in vivo MRS in the human brain Quantitation of a spin polarization-induced nuclear Overhauser effect (SPINOE) between a hyperpolarized (13) C-labeled cell metabolite and water protons.Intratumor mapping of intracellular water lifetime: metabolic images of breast cancer?MR Molecular Imaging of Brain Cancer Metabolism Using Hyperpolarized 13C Magnetic Resonance Spectroscopy.High resolution (13)C MRI with hyperpolarized urea: in vivo T(2) mapping and (15)N labeling effects Functional and molecular imaging with MRI: potential applications in paediatric radiology.Detection of tumor response to a vascular disrupting agent by hyperpolarized 13C magnetic resonance spectroscopy.Magnetic resonance spectroscopy in metabolic and molecular imaging and diagnosis of cancer Magnetic resonance in the era of molecular imaging of cancer DNP by thermal mixing under optimized conditions yields >60,000-fold enhancement of 89Y NMR signal.Multi-compound polarization by DNP allows simultaneous assessment of multiple enzymatic activities in vivo A hyperpolarized choline molecular probe for monitoring acetylcholine synthesis.Applications of molecular MRI and optical imaging in cancer.Synthesis and testing of a p-H2 hyperpolarized 13C probe based on the pyrazolo[1,5-a]pyrimidineacetamide DPA-713, an MRI vector to target the peripheral benzodiazepine receptors.Hyperpolarized (13)C spectroscopy detects early changes in tumor vasculature and metabolism after VEGF neutralization.Detecting treatment response in a model of human breast adenocarcinoma using hyperpolarised [1-13C]pyruvate and [1,4-13C2]fumarate On-target inhibition of tumor fermentative glycolysis as visualized by hyperpolarized pyruvate.Hyperpolarized singlet lifetimes of pyruvate in human blood and in the mouse.Analysis of cancer metabolism by imaging hyperpolarized nuclei: prospects for translation to clinical research.A hydrogen peroxide-responsive hyperpolarized 13C MRI contrast agent.Dephosphorylation and biodistribution of 1-¹³C-phospholactate in vivo.Could 13C MRI assist clinical decision-making for patients with heart disease?Hyperpolarized magnetic resonance: a novel technique for the in vivo assessment of cardiovascular disease.High-field small animal magnetic resonance oncology studies.NMR hyperpolarization techniques for biomedicine.Flux through hepatic pyruvate carboxylase and phosphoenolpyruvate carboxykinase detected by hyperpolarized 13C magnetic resonance.Monitoring chemotherapeutic response by hyperpolarized 13C-fumarate MRS and diffusion MRI.

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Production of hyperpolarized [1,4-13C2]malate from [1,4-13C2]fumarate is a marker of cell necrosis and treatment response in tumors.

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Production of hyperpolarized [ ...... treatment response in tumors.

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P2860

Increase in signal-to-noise ratio of > 10,000 times in liquid-state NMR

New response evaluation criteria in solid tumours: revised RECIST guideline (version 1.1)

Cytokeratin-18 is a useful serum biomarker for early determination of response of breast carcinomas to chemotherapy

Diffusion-weighted MRI in the body: applications and challenges in oncology.

Detecting tumor response to treatment using hyperpolarized 13C magnetic resonance imaging and spectroscopy.

Seeing into cells. The promise of in vivo molecular imaging in oncology

Four deaths and a funeral: from caspases to alternative mechanisms.

Dimethylfumarate for psoriasis: more than a dietary curiosity.

Fumaric Acid and its esters: an emerging treatment for multiple sclerosis.

Interactions between lithium and renal transport of Krebs cycle intermediates.

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