Production of hyperpolarized [1,4-13C2]malate from [1,4-13C2]fumarate is a marker of cell necrosis and treatment response in tumors.
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Potential Clinical Roles for Metabolic Imaging with Hyperpolarized [1-(13)C]PyruvateHyperpolarized (13)C Magnetic Resonance and Its Use in Metabolic Assessment of Cultured Cells and Perfused OrgansImaging radiation response in tumor and normal tissue.Biomarkers and molecular probes for cell death imaging and targeted therapeuticsHyperpolarized magnetic resonance as a sensitive detector of metabolic functionChemistry and biochemistry of 13C hyperpolarized magnetic resonance using dynamic nuclear polarizationClinical implications of cardiac hyperpolarized magnetic resonance imagingImaging metabolic heterogeneity in cancerPreclinical assessment of carboplatin treatment efficacy in lung cancer by 18F-ICMT-11-positron emission tomographyMR Imaging Biomarkers in Oncology Clinical TrialsHyperpolarization MRI: Preclinical Models and Potential Applications in Neuroradiology.Biomarkers in preclinical cancer imaging.Current and emerging quantitative magnetic resonance imaging methods for assessing and predicting the response of breast cancer to neoadjuvant therapy.Glutamate and glutamine: a review of in vivo MRS in the human brainQuantitation of a spin polarization-induced nuclear Overhauser effect (SPINOE) between a hyperpolarized (13) C-labeled cell metabolite and water protons.Intratumor mapping of intracellular water lifetime: metabolic images of breast cancer?MR Molecular Imaging of Brain Cancer Metabolism Using Hyperpolarized 13C Magnetic Resonance Spectroscopy.High resolution (13)C MRI with hyperpolarized urea: in vivo T(2) mapping and (15)N labeling effectsFunctional and molecular imaging with MRI: potential applications in paediatric radiology.Detection of tumor response to a vascular disrupting agent by hyperpolarized 13C magnetic resonance spectroscopy.Magnetic resonance spectroscopy in metabolic and molecular imaging and diagnosis of cancerMagnetic resonance in the era of molecular imaging of cancerDNP by thermal mixing under optimized conditions yields >60,000-fold enhancement of 89Y NMR signal.Multi-compound polarization by DNP allows simultaneous assessment of multiple enzymatic activities in vivoA hyperpolarized choline molecular probe for monitoring acetylcholine synthesis.Applications of molecular MRI and optical imaging in cancer.Synthesis and testing of a p-H2 hyperpolarized 13C probe based on the pyrazolo[1,5-a]pyrimidineacetamide DPA-713, an MRI vector to target the peripheral benzodiazepine receptors.Hyperpolarized (13)C spectroscopy detects early changes in tumor vasculature and metabolism after VEGF neutralization.Detecting treatment response in a model of human breast adenocarcinoma using hyperpolarised [1-13C]pyruvate and [1,4-13C2]fumarateOn-target inhibition of tumor fermentative glycolysis as visualized by hyperpolarized pyruvate.Hyperpolarized singlet lifetimes of pyruvate in human blood and in the mouse.Analysis of cancer metabolism by imaging hyperpolarized nuclei: prospects for translation to clinical research.A hydrogen peroxide-responsive hyperpolarized 13C MRI contrast agent.Dephosphorylation and biodistribution of 1-¹³C-phospholactate in vivo.Could 13C MRI assist clinical decision-making for patients with heart disease?Hyperpolarized magnetic resonance: a novel technique for the in vivo assessment of cardiovascular disease.High-field small animal magnetic resonance oncology studies.NMR hyperpolarization techniques for biomedicine.Flux through hepatic pyruvate carboxylase and phosphoenolpyruvate carboxykinase detected by hyperpolarized 13C magnetic resonance.Monitoring chemotherapeutic response by hyperpolarized 13C-fumarate MRS and diffusion MRI.
P2860
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P2860
Production of hyperpolarized [1,4-13C2]malate from [1,4-13C2]fumarate is a marker of cell necrosis and treatment response in tumors.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
@zh
2009年學術文章
@zh-hant
name
Production of hyperpolarized [ ...... treatment response in tumors.
@en
Production of hyperpolarized [ ...... treatment response in tumors.
@nl
type
label
Production of hyperpolarized [ ...... treatment response in tumors.
@en
Production of hyperpolarized [ ...... treatment response in tumors.
@nl
prefLabel
Production of hyperpolarized [ ...... treatment response in tumors.
@en
Production of hyperpolarized [ ...... treatment response in tumors.
@nl
P2093
P2860
P50
P356
P1476
Production of hyperpolarized [ ...... treatment response in tumors.
@en
P2093
Anna Gisselsson
Georg Hansson
Kevin M Brindle
René In 't Zandt
Sarah K Nelson
Torben Peitersen
P2860
P304
19801-19806
P356
10.1073/PNAS.0911447106
P407
P50
P577
2009-11-10T00:00:00Z