Antiprogestin mifepristone inhibits the growth of cancer cells of reproductive and non-reproductive origin regardless of progesterone receptor expression.
about
Systemic therapy of Cushing's syndromeResistance to cisplatin and paclitaxel does not affect the sensitivity of human ovarian cancer cells to antiprogestin-induced cytotoxicityProgesterone induces the growth and infiltration of human astrocytoma cells implanted in the cerebral cortex of the rat.Mifepristone prevents repopulation of ovarian cancer cells escaping cisplatin-paclitaxel therapy.Cytostasis and morphological changes induced by mifepristone in human metastatic cancer cells involve cytoskeletal filamentous actin reorganization and impairment of cell adhesion dynamicsAntiprogestins in gynecological diseases.Systems pharmacology of mifepristone (RU486) reveals its 47 hub targets and network: comprehensive analysis and pharmacological focus on FAK-Src-Paxillin complex.Antihormonal agents as a strategy to improve the effect of chemo-radiation in cervical cancer: in vitro and in vivo studyProgestin and antiprogestin responsiveness in breast cancer is driven by the PRA/PRB ratio via AIB1 or SMRT recruitment to the CCND1 and MYC promoters.Progesterone inhibits the growth of human neuroblastoma: in vitro and in vivo evidence.Glucocorticoid receptor activity contributes to resistance to androgen-targeted therapy in prostate cancerThe Role of Mifepristone in Meningiomas Management: A Systematic Review of the LiteratureDrug Repurposing for Cancer Therapy.Synergistic lethality of mifepristone and LY294002 in ovarian cancer cellsMifepristone Suppresses Basal Triple-Negative Breast Cancer Stem Cells by Down-regulating KLF5 Expression.Mifepristone improves chemo-radiation response in glioblastoma xenografts.The unique pharmacological characteristics of mifepristone (RU486): from terminating pregnancy to preventing cancer metastasis.Selective Glucocorticoid Receptor Modulators (SGRMs) Delay Castrate-Resistant Prostate Cancer Growth.Mifepristone increases mRNA translation rate, triggers the unfolded protein response, increases autophagic flux, and kills ovarian cancer cells in combination with proteasome or lysosome inhibitors.Progesterone antagonist, RU486, represses LHCGR expression and LH/hCG signaling in cultured luteinized human mural granulosa cells.Computational repositioning and preclinical validation of mifepristone for human vestibular schwannoma.Ovarian steroid hormones modulate the expression of progesterone receptors and histone acetylation patterns in uterine leiomyoma cells.Drug Repositioning for Effective Prostate Cancer Treatment.
P2860
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P2860
Antiprogestin mifepristone inhibits the growth of cancer cells of reproductive and non-reproductive origin regardless of progesterone receptor expression.
description
2011 nî lūn-bûn
@nan
2011 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Antiprogestin mifepristone inh ...... gesterone receptor expression.
@ast
Antiprogestin mifepristone inh ...... gesterone receptor expression.
@en
type
label
Antiprogestin mifepristone inh ...... gesterone receptor expression.
@ast
Antiprogestin mifepristone inh ...... gesterone receptor expression.
@en
prefLabel
Antiprogestin mifepristone inh ...... gesterone receptor expression.
@ast
Antiprogestin mifepristone inh ...... gesterone receptor expression.
@en
P2093
P2860
P356
P1433
P1476
Antiprogestin mifepristone inh ...... ogesterone receptor expression
@en
P2093
Alicia A Goyeneche
BreeAnn N Brandhagen
Casey T Ortbahn
Chelsea R Tieszen
P2860
P2888
P356
10.1186/1471-2407-11-207
P407
P577
2011-05-27T00:00:00Z
P5875
P6179
1038033267