Cultured hypothalamic neurons are resistant to inflammation and insulin resistance induced by saturated fatty acids
about
Central nervous system mechanisms linking the consumption of palatable high-fat diets to the defense of greater adiposityIncreasing fatty acid oxidation remodels the hypothalamic neurometabolome to mitigate stress and inflammationMinireview: Inflammation and obesity pathogenesis: the hypothalamus heats up.Lipid-induced insulin resistance mediated by the proinflammatory receptor TLR4 requires saturated fatty acid-induced ceramide biosynthesis in mice.Enteric neuropathy can be induced by high fat diet in vivo and palmitic acid exposure in vitro.Saturated fatty acids modulate autophagy's proteins in the hypothalamusDefective hypothalamic autophagy directs the central pathogenesis of obesity via the IkappaB kinase beta (IKKbeta)/NF-kappaB pathwayHypothalamic inflammation: a double-edged sword to nutritional diseases.Deficiency of lymphotoxin-α does not exacerbate high-fat diet-induced obesity but does enhance inflammation in mice.Obesity induces hypothalamic endoplasmic reticulum stress and impairs proopiomelanocortin (POMC) post-translational processing.Fatting the brain: a brief of recent researchDifferential acute and chronic effects of leptin on hypothalamic astrocyte morphology and synaptic protein levels.Mild lipid stress induces profound loss of MC4R protein abundance and function.Bone marrow-CNS connections: implications in the pathogenesis of diabetic retinopathyLeptin resistance in diet-induced obesity: the role of hypothalamic inflammation.Leptin signaling as a therapeutic target of obesity.Hypothalamic innate immune reaction in obesity.Hypothalamic ER stress: A bridge between leptin resistance and obesity.LPS-Induced Low-Grade Inflammation Increases Hypothalamic JNK Expression and Causes Central Insulin Resistance Irrespective of Body Weight Changes.Effects of Fat and Sugar, Either Consumed or Infused toward the Brain, on Hypothalamic ER Stress Markers.Cell culture models of fatty acid overload: Problems and solutions.Central Regulation of Glucose Homeostasis.One-Week Exposure to a Free-Choice High-Fat High-Sugar Diet Does Not Interfere With the Lipopolysaccharide-Induced Acute Phase Response in the Hypothalamus of Male Rats.Links Between Obesity-Induced Brain Insulin Resistance, Brain Mitochondrial Dysfunction, and Dementia
P2860
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P2860
Cultured hypothalamic neurons are resistant to inflammation and insulin resistance induced by saturated fatty acids
description
2010 nî lūn-bûn
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2010 թուականի Մարտին հրատարակուած գիտական յօդուած
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2010 թվականի մարտին հրատարակված գիտական հոդված
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2010年の論文
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2010年学术文章
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2010年学术文章
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2010年学术文章
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2010年学术文章
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2010年学术文章
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2010年學術文章
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name
Cultured hypothalamic neurons ...... duced by saturated fatty acids
@ast
Cultured hypothalamic neurons ...... duced by saturated fatty acids
@en
type
label
Cultured hypothalamic neurons ...... duced by saturated fatty acids
@ast
Cultured hypothalamic neurons ...... duced by saturated fatty acids
@en
prefLabel
Cultured hypothalamic neurons ...... duced by saturated fatty acids
@ast
Cultured hypothalamic neurons ...... duced by saturated fatty acids
@en
P2093
P2860
P921
P1476
Cultured hypothalamic neurons ...... duced by saturated fatty acids
@en
P2093
Brent E Wisse
Francis Kim
Michael W Schwartz
Sun Ju Choi
P2860
P304
P356
10.1152/AJPENDO.00006.2010
P577
2010-03-30T00:00:00Z