Calcineurin cleavage is triggered by elevated intraocular pressure, and calcineurin inhibition blocks retinal ganglion cell death in experimental glaucoma - Wikidata - wikimedia - TriplyDB

Calcineurin cleavage is triggered by elevated intraocular pressure, and calcineurin inhibition blocks retinal ganglion cell death in experimental glaucoma

Calcineurin cleavage is triggered by elevated intraocular pressure, and calcineurin inhibition blocks retinal ganglion cell death in experimental glaucoma

http://www.wikidata.org/entity/Q33917505

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Intraocular Pressure Induced Retinal Changes Identified Using Synchrotron Infrared Microscopy Mechanisms of noise-induced hearing loss indicate multiple methods of prevention.Downregulation of Thy1 in retinal ganglion cells in experimental glaucoma.Rgcs1, a dominant QTL that affects retinal ganglion cell death after optic nerve crush in mice.Calpain activation in experimental glaucoma.Amyloid beta induces the morphological neurodegenerative triad of spine loss, dendritic simplification, and neuritic dystrophies through calcineurin activation.Efficient estimation of retinal ganglion cell number: a stereological approach Variations in the rheostat model of apoptosis: what studies of retinal ganglion cell death tell us about the functions of the Bcl2 family proteins.Cyclosporin A enhances neural precursor cell survival in mice through a calcineurin-independent pathway Complement mediated apoptosis leads to the loss of retinal ganglion cells in animal model of glaucoma.sCD44 internalization in human trabecular meshwork cells.Neurodegeneration in glaucoma: progression and calcium-dependent intracellular mechanisms.In glaucoma the upregulated truncated TrkC.T1 receptor isoform in glia causes increased TNF-alpha production, leading to retinal ganglion cell death.Mouse models of retinal ganglion cell death and glaucoma.Development of spontaneous neuropathy in NF-κBp50-deficient mice by calcineurin-signal involving impaired NF-κB activation.Celastrol supports survival of retinal ganglion cells injured by optic nerve crush.The role of calcineurin signaling in microcystin-LR triggered neuronal toxicity.Distinct dendritic spine and nuclear phases of calcineurin activation after exposure to amyloid-β revealed by a novel fluorescence resonance energy transfer assay.Calcineurin activation causes retinal ganglion cell degeneration.Blockade of Astrocytic Calcineurin/NFAT Signaling Helps to Normalize Hippocampal Synaptic Function and Plasticity in a Rat Model of Traumatic Brain Injury.TRPV1: contribution to retinal ganglion cell apoptosis and increased intracellular Ca2+ with exposure to hydrostatic pressure.Differential expression of the catalytic subunits for PP-1 and PP-2A and the regulatory subunits for PP-2A in mouse eye.Phosphorylation-dependent interaction with 14-3-3 in the regulation of bad trafficking in retinal ganglion cells.Heat shock proteins in the retina: Focus on HSP70 and alpha crystallins in ganglion cell survival.Alpha2-macroglobulin is a mediator of retinal ganglion cell death in glaucoma.Reliability and sensitivity of the TonoLab rebound tonometer in awake Brown Norway rats The cell and molecular biology of glaucoma: mechanisms of retinal ganglion cell death.Mechanisms of retinal ganglion cell injury and defense in glaucoma.Development of diagnostic and treatment strategies for glaucoma through understanding and modification of scleral and lamina cribrosa connective tissue Neuroprotective therapies for glaucoma.BAX to basics: How the BCL2 gene family controls the death of retinal ganglion cells.Epigenetics and Signaling Pathways in Glaucoma.Effects of crystallin-β-b2 on stressed RPE in vitro and in vivo.FKBP51 protects 661w cell culture from staurosporine-induced apoptosis.Characterization of the intracellular proteolytic cleavage of myocilin and identification of calpain II as a myocilin-processing protease.Calcineurin/NFAT Signaling in Activated Astrocytes Drives Network Hyperexcitability in Aβ-Bearing Mice.Calcineurin proteolysis in astrocytes: Implications for impaired synaptic function Pycnogenol protects CA3-CA1 synaptic function in a rat model of traumatic brain injury Calcineurin inhibition with FK506 ameliorates dendritic spine density deficits in plaque-bearing Alzheimer model mice Protection of neurons from apoptosis by apolipoprotein E-containing lipoproteins does not require lipoprotein uptake and involves activation of phospholipase Cgamma1 and inhibition of calcineurin.

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P2860

Calcineurin cleavage is triggered by elevated intraocular pressure, and calcineurin inhibition blocks retinal ganglion cell death in experimental glaucoma

http://www.wikidata.org/entity/Q33917505

description

2005 nî lūn-bûn

@nan

2005 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2005 թվականի օգոստոսին հրատարակված գիտական հոդված

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2005年の論文

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2005年学术文章

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2005年学术文章

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2005年学术文章

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2005年学术文章

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2005年学术文章

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2005年學術文章

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name

Calcineurin cleavage is trigge ...... death in experimental glaucoma

@ast

Calcineurin cleavage is trigge ...... death in experimental glaucoma

@en

type

label

Calcineurin cleavage is trigge ...... death in experimental glaucoma

@ast

Calcineurin cleavage is trigge ...... death in experimental glaucoma

@en

prefLabel

Calcineurin cleavage is trigge ...... death in experimental glaucoma

@ast

Calcineurin cleavage is trigge ...... death in experimental glaucoma

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PNAS.0505138102

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Proceedings of the National Academy of Sciences of the United States of America

P1476

Calcineurin cleavage is trigge ...... death in experimental glaucoma

@en

P2093

Adam Dobberfuhl

http://www.w3.org/2001/XMLSchema#string

Cynthia L Grosskreutz

http://www.w3.org/2001/XMLSchema#string

Gina Kwon

http://www.w3.org/2001/XMLSchema#string

John B Fileta

http://www.w3.org/2001/XMLSchema#string

Theodoros Filippopolous

http://www.w3.org/2001/XMLSchema#string

Wei Huang

http://www.w3.org/2001/XMLSchema#string

Yan Guo

http://www.w3.org/2001/XMLSchema#string

P2860

Ca2+-induced apoptosis through calcineurin dephosphorylation of BAD

FK506 prevents stroke-induced generation of ceramide and apoptosis signaling

Calcineurin/NFAT-induced up-regulation of the Fas ligand/Fas death pathway is involved in methamphetamine-induced neuronal apoptosis

A second calcineurin binding site on the NFAT regulatory domain

Unbiased stereological estimation of the total number of neurons in thesubdivisions of the rat hippocampus using the optical fractionator

Localization of calcineurin in the mature and developing retina.

Caspase activation and amyloid precursor protein cleavage in rat ocular hypertension.

Critical role of calpain-mediated cleavage of calcineurin in excitotoxic neurodegeneration.

FK506 prevents mitochondrial-dependent apoptotic cell death induced by 3-nitropropionic acid in rat primary cortical cultures.

FK506, an immunosuppressant targeting calcineurin function.

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34

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7657990

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1186026

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