Distinct dendritic spine and nuclear phases of calcineurin activation after exposure to amyloid-β revealed by a novel fluorescence resonance energy transfer assay.
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Targeting the proper amyloid-beta neuronal toxins: a path forward for Alzheimer's disease immunotherapeuticsThe dendritic hypothesis for Alzheimer's disease pathophysiology.The Emerging Roles of the Calcineurin-Nuclear Factor of Activated T-Lymphocytes Pathway in Nervous System Functions and DiseasesDynamic visualization of calcium-dependent signaling in cellular microdomainsAmyloid-β oligomers induce tau-independent disruption of BDNF axonal transport via calcineurin activation in cultured hippocampal neuronsDendritic and axonal mechanisms of Ca2+ elevation impair BDNF transport in Aβ oligomer-treated hippocampal neuronsThe intersection of amyloid beta and tau at synapses in Alzheimer's diseaseCalmodulin-controlled spatial decoding of oscillatory Ca2+ signals by calcineurin.Type 1 cannabinoid receptor ligands display functional selectivity in a cell culture model of striatal medium spiny projection neurons.Life extension factor klotho prevents mortality and enhances cognition in hAPP transgenic mice.Attenuation of microglial activation in a mouse model of Alzheimer's disease via NFAT inhibitionMitochondria-Targeted Antioxidant SS31 Prevents Amyloid Beta-Induced Mitochondrial Abnormalities and Synaptic Degeneration in Alzheimer's DiseaseNMDA receptor subunit composition determines beta-amyloid-induced neurodegeneration and synaptic loss.Synaptic alterations in the rTg4510 mouse model of tauopathy.Interrelationship between changes in the amyloid β 42/40 ratio and presenilin 1 conformationSoluble oligomeric amyloid-β induces calcium dyshomeostasis that precedes synapse loss in the living mouse brain.Genetically encoded fluorescent biosensors for live-cell visualization of protein phosphorylation.Mechanisms and dynamics of AKAP79/150-orchestrated multi-protein signalling complexes in brain and peripheral nerve.Formation, release, and internalization of stable tau oligomers in cells.TrkB activation by 7, 8-dihydroxyflavone increases synapse AMPA subunits and ameliorates spatial memory deficits in a mouse model of Alzheimer's disease.Atorvastatin prevents Aβ oligomer-induced neurotoxicity in cultured rat hippocampal neurons by inhibiting Tau cleavageIntracellular amyloid β oligomers impair organelle transport and induce dendritic spine loss in primary neurons.Targeting astrocytes ameliorates neurologic changes in a mouse model of Alzheimer's disease.Activity-dependent transcriptional regulation of M-Type (Kv7) K(+) channels by AKAP79/150-mediated NFAT actions.NFATc2 Modulates Microglial Activation in the AβPP/PS1 Mouse Model of Alzheimer's Disease.Potential for therapeutic targeting of AKAP signaling complexes in nervous system disorders.Mitochondria-targeted small molecule SS31: a potential candidate for the treatment of Alzheimer's disease.Pin1 mediates Aβ42-induced dendritic spine loss.
P2860
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P2860
Distinct dendritic spine and nuclear phases of calcineurin activation after exposure to amyloid-β revealed by a novel fluorescence resonance energy transfer assay.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Distinct dendritic spine and n ...... sonance energy transfer assay.
@ast
Distinct dendritic spine and n ...... sonance energy transfer assay.
@en
type
label
Distinct dendritic spine and n ...... sonance energy transfer assay.
@ast
Distinct dendritic spine and n ...... sonance energy transfer assay.
@en
prefLabel
Distinct dendritic spine and n ...... sonance energy transfer assay.
@ast
Distinct dendritic spine and n ...... sonance energy transfer assay.
@en
P2093
P2860
P1476
Distinct dendritic spine and n ...... sonance energy transfer assay.
@en
P2093
Brian J Bacskai
Cynthia L Grosskreutz
Eloise Hudry
Hai-Yan Wu
Kengo Uemura
Oksana Berezovska
Tadafumi Hashimoto
Zhan-Yun Fan
P2860
P304
P356
10.1523/JNEUROSCI.0227-12.2012
P407
P577
2012-04-01T00:00:00Z