The amplified H circle of methotrexate-resistant leishmania tarentolae contains a novel P-glycoprotein gene
about
Expression of the MRP gene-encoded conjugate export pump in liver and its selective absence from the canalicular membrane in transport-deficient mutant hepatocytesInduction of resistance to azole drugs in Trypanosoma cruzi.Structural, functional, and evolutionary relationships among extracellular solute-binding receptors of bacteriaFormation of extrachromosomal circular amplicons with direct or inverted duplications in drug-resistant Leishmania tarentolaePhysiological consequences of drug resistance in Leishmania and their relevance for chemotherapyHomologues of the human multidrug resistance genes MRP and MDR contribute to heavy metal resistance in the soil nematode Caenorhabditis elegansUnresponsiveness to Glucantime treatment in Iranian cutaneous leishmaniasis due to drug-resistant Leishmania tropica parasites.Gene expression profiling and molecular characterization of antimony resistance in Leishmania amazonensisMultiple mutations in heterogeneous miltefosine-resistant Leishmania major population as determined by whole genome sequencingGeneration of Leishmania hybrids by whole genomic DNA transformationDrug resistance in natural isolates of Leishmania donovani s.l. promastigotes is dependent of Pgp170 expressionIntrachromosomal amplification, locus deletion and point mutation in the aquaglyceroporin AQP1 gene in antimony resistant Leishmania (Viannia) guyanensisThe role of alanine 163 in solute permeability of Leishmania major aquaglyceroporin LmAQP1Multidrug resistance in Leishmania donovani is conferred by amplification of a gene homologous to the mammalian mdr1 geneIsolation and characterization of Drosophila multidrug resistance gene homologs.Amplification of adenine phosphoribosyltransferase suppresses the conditionally lethal growth and virulence phenotype of Leishmania donovani mutants lacking both hypoxanthine-guanine and xanthine phosphoribosyltransferases.Frequency of drug resistance gene amplification in clinical leishmania strainsHeterogeneity of molecular resistance patterns in antimony-resistant field isolates of Leishmania species from the western Mediterranean area.P-glycoprotein A Gene Expression in Glucantime-Resistant and Sensitive Leishmania major (MRHO/IR/75/ER)Gene amplification and point mutations in pyrimidine metabolic genes in 5-fluorouracil resistant Leishmania infantum.Modulation of Leishmania ABC protein gene expression through life stages and among drug-resistant parasites.Antimony resistance in leishmania, focusing on experimental research.Overexpression of the gene encoding the multidrug resistance-associated protein results in increased ATP-dependent glutathione S-conjugate transport.Modulation of Leishmania major aquaglyceroporin activity by a mitogen-activated protein kinase.P-glycoprotein structure and evolutionary homologies.Moving from unsequenced to sequenced genome: reanalysis of the proteome of Leishmania donovani.Increased expression of LD1 genes transcribed by RNA polymerase I in Leishmania donovani as a result of duplication into the rRNA gene locus.Unstable amplification of two extrachromosomal elements in alpha-difluoromethylornithine-resistant Leishmania donovani.Geographical Distribution of MDR1 Expression in Leishmania Isolates, from Greece and Cyprus, Measured by the Rhodamine-123 Efflux Potential of the Isolates, Using Flow Cytometry.Induced resistance to methionyl-tRNA synthetase inhibitors in Trypanosoma brucei is due to overexpression of the target.A new ABC half-transporter in Leishmania major is involved in resistance to antimony.Alteration in glycerol and metalloid permeability by a single mutation in the extracellular C-loop of Leishmania major aquaglyceroporin LmAQP1.Molecular characterization of the MRPA transporter and antimony uptake in four New World Leishmania spp. susceptible and resistant to antimony.Susceptibility of an emetine-resistant mutant of Entamoeba histolytica to multiple drugs and to channel blockers.Gene amplification in Leishmania tarentolae selected for resistance to sodium stibogluconate.The Leishmania genome comprises 36 chromosomes conserved across widely divergent human pathogenic species.Modulation of gene expression in human macrophages treated with the anti-leishmania pentavalent antimonial drug sodium stibogluconate.Co-existence of circular and multiple linear amplicons in methotrexate-resistant LeishmaniaHomologous recombination between direct repeat sequences yields P-glycoprotein containing amplicons in arsenite resistant Leishmania.Frequent amplification of a short chain dehydrogenase gene as part of circular and linear amplicons in methotrexate resistant Leishmania
P2860
Q24310772-E224C6E3-7541-4294-A885-EAFEEFEA76B9Q24519052-CC040299-D0A3-4F48-8FA9-D2B75D0F463DQ24634676-62C2EB8D-C02D-4D1B-B598-8D64C0356789Q24648956-2B898F60-A535-412D-B503-FADDC705AA02Q24796588-961D7EF1-69C4-46D7-9F6A-C44D59F438EEQ28379341-37605FA8-6C23-4645-9E14-AB8FCA0A0330Q28468760-A8027A66-5FDC-4817-A876-76449B7219A1Q28478242-CA33566E-3A65-4572-8636-2C6EE113E1D8Q28480626-24514F4A-BE33-41A6-900E-C1FA429B4A84Q28483925-B4AB07E9-2B16-4906-8BF0-72C65A41B076Q28533820-C2AEB68E-0165-41D9-8C20-DEE1287D659DQ28543469-25C4FA55-D22B-4450-AB11-023272542B6AQ30497265-D6195D62-9329-4197-93EE-29473C72155DQ31162495-2F9E8A79-B5A5-4FAB-AB45-F7621DAB6903Q33668301-FC108F71-D734-4747-AC58-E286D023D595Q33897846-A70B8B99-63C1-4BE5-B5D0-FE25DE659D3EQ34034590-F41E7AD3-FB6D-4C8D-BBFD-23B1F22654CDQ34058276-2DAF1D05-B7E3-46C3-8E76-D17A932723B1Q35047361-9E10ACFC-12A3-4592-A597-2E91D6784AA7Q35054195-B1E68686-D930-426F-9DA4-E063F95864E8Q35075211-299A0ECE-B984-42E5-A717-46C2F9AE7F72Q35607561-DAC889D3-AD73-4BF1-944A-73479B6F6005Q36019240-C043BB74-8534-4B00-8069-F16F2BA9C5A6Q36223332-0A062863-F62A-48F6-A85D-C09CA051A2E3Q36254844-D745285F-1628-4CC4-8624-98EEB71F5DA9Q36454920-A1365CEE-7CED-4FED-AAAE-09FEC9DCE06DQ36556343-20F9791B-B31F-406A-9452-C19BE245C6E3Q36706604-9BE330E3-FEB5-4B98-99FB-744BA2AEAAA7Q36869654-A0558356-76E4-4849-91A7-A9488E81B692Q36969804-7EB0AB1D-5BF7-4CCC-900C-901FA73F4591Q37036630-1CF107D3-D53F-41EC-B880-94DD233B935FQ37243437-BB3B20A0-FD0B-47EC-B10B-7BC90D9BDC3DQ37390612-119E91FC-B815-4023-A0A2-9B2E60F93A60Q39427240-E312D935-7233-4ABC-A8EA-FAAB40BB8587Q39557983-12F83766-68DF-4D04-9277-B8CA3B90A6DDQ39716216-AFEC24F0-AAC7-43ED-A6F8-FE258D22A3A5Q40037079-E6D45B00-C844-4353-A4B5-6354C2F3ECEFQ40395129-C5F77B6B-6B82-4EB2-8FF2-8B1C8B9AAFD8Q40406581-E30B9E71-EA2B-413B-A65A-5E242D164430Q40409983-70C9FE4D-5C06-44AA-9C59-56CE5ABB64FE
P2860
The amplified H circle of methotrexate-resistant leishmania tarentolae contains a novel P-glycoprotein gene
description
1990 nî lūn-bûn
@nan
1990 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1990 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1990年の論文
@ja
1990年論文
@yue
1990年論文
@zh-hant
1990年論文
@zh-hk
1990年論文
@zh-mo
1990年論文
@zh-tw
1990年论文
@wuu
name
The amplified H circle of meth ...... ns a novel P-glycoprotein gene
@ast
The amplified H circle of meth ...... ns a novel P-glycoprotein gene
@en
type
label
The amplified H circle of meth ...... ns a novel P-glycoprotein gene
@ast
The amplified H circle of meth ...... ns a novel P-glycoprotein gene
@en
prefLabel
The amplified H circle of meth ...... ns a novel P-glycoprotein gene
@ast
The amplified H circle of meth ...... ns a novel P-glycoprotein gene
@en
P2093
P2860
P1433
P1476
The amplified H circle of meth ...... ns a novel P-glycoprotein gene
@en
P2093
F Fase-Fowler
M Ouellette
P2860
P304
P356
10.1002/J.1460-2075.1990.TB08206.X
P407
P577
1990-04-01T00:00:00Z