Complete antithrombin deficiency in mice results in embryonic lethality. - Wikidata - wikimedia - TriplyDB

Complete antithrombin deficiency in mice results in embryonic lethality.

Complete antithrombin deficiency in mice results in embryonic lethality.

http://www.wikidata.org/entity/Q33920163

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Heparin cofactor II inhibits arterial thrombosis after endothelial injury A nonsense polymorphism in the protein Z-dependent protease inhibitor increases the risk for venous thrombosis Inhibition of antithrombin by hyaluronic acid may be involved in the pathogenesis of rheumatoid arthritis.Cytoprotective-selective activated protein C therapy for ischaemic stroke Type II antithrombin deficiency caused by a large in-frame insertion: structural, functional and pathological relevance Endothelium-specific loss of murine thrombomodulin disrupts the protein C anticoagulant pathway and causes juvenile-onset thrombosis Ancestry and evolution of a secretory pathway serpin The critical role of hinge-region expulsion in the induced-fit heparin binding mechanism of antithrombin.Genomic regions that influence plasma levels of inflammatory markers in hypertensive sibships.Antithrombin reduces reperfusion-induced hepatic metastasis of colon cancer cells.Targeted mutagenesis of zebrafish antithrombin III triggers disseminated intravascular coagulation and thrombosis, revealing insight into function.Zebrafish as a model system for the study of hemostasis and thrombosis.Conformational activation of antithrombin by heparin involves an altered exosite interaction with protease.Normal levels of anticoagulant heparan sulfate are not essential for normal hemostasis Increased expression of plasminogen activator inhibitor-1 in cardiomyocytes contributes to cardiac fibrosis after myocardial infarction.Inherited trombophilic states and pulmonary embolism.Heparan sulfate: antithrombotic or not?Matriptase is inhibited by extravascular antithrombin in epithelial cells but not in most carcinoma cells Modeling Disorders of Blood Coagulation in the Zebrafish.Identification of Regulatory Mutations in SERPINC1 Affecting Vitamin D Response Elements Associated with Antithrombin Deficiency.Saturation Mutagenesis of the Antithrombin Reactive Center Loop P14 Residue Supports a Three-step Mechanism of Heparin Allosteric Activation Involving Intermediate and Fully Activated States Accelerated atherogenesis and neointima formation in heparin cofactor II deficient mice.Vascular dermatan sulfate regulates the antithrombotic activity of heparin cofactor II Protein Z-dependent protease inhibitor deficiency produces a more severe murine phenotype than protein Z deficiency.Control of post-translational modifications in antithrombin during murine post-natal development by miR-200a Pharmacokinetics of protein C and antithrombin in the fetal lamb: a model to predict human neonatal replacement dosing.Functional consequences of the prothrombotic SERPINC1 rs2227589 polymorphism on antithrombin levels Tissue factor-dependent coagulation contributes to alpha-naphthylisothiocyanate-induced cholestatic liver injury in mice.AbetaPP/APLP2 family of Kunitz serine proteinase inhibitors regulate cerebral thrombosis.The signature 3-O-sulfo group of the anticoagulant heparin sequence is critical for heparin binding to antithrombin but is not required for allosteric activation.Plasmodium falciparum picks (on) EPCR.Molecular mechanisms of antithrombin-heparin regulation of blood clotting proteinases. A paradigm for understanding proteinase regulation by serpin family protein proteinase inhibitors.The phenotypic and genetic assessment of antithrombin deficiency.Historical perspective and future direction of coagulation research.Lysine 114 of antithrombin is of crucial importance for the affinity and kinetics of heparin pentasaccharide binding.The influence of the amyloid ß-protein and its precursor in modulating cerebral hemostasis.Identification and function probing of an antithrombin IIIβ conformation-specific antibody.Inhibitory serpins. New insights into their folding, polymerization, regulation and clearance.L-asparaginase-induced antithrombin type I deficiency: implications for conformational diseases.The heparin-binding site of antithrombin is crucial for antiangiogenic activity

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P2860

Complete antithrombin deficiency in mice results in embryonic lethality.

http://www.wikidata.org/entity/Q33920163

description

2000 nî lūn-bûn

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2000 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2000 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2000年の論文

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2000年論文

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2000年論文

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2000年論文

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2000年論文

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2000年論文

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2000年论文

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name

Complete antithrombin deficiency in mice results in embryonic lethality.

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Complete antithrombin deficiency in mice results in embryonic lethality.

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Complete antithrombin deficiency in mice results in embryonic lethality.

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Complete antithrombin deficiency in mice results in embryonic lethality.

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Complete antithrombin deficiency in mice results in embryonic lethality.

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Complete antithrombin deficiency in mice results in embryonic lethality.

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Journal of Clinical Investigation

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Complete antithrombin deficiency in mice results in embryonic lethality.

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P2093

A Takagi

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H Saito

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K Kadomatsu

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K Kusugami

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K Yamamoto

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M Ito

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M Suzuki

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N Takeda

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T Kojima

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T Matsushita

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P2860

Heparan sulfate proteoglycans of the cardiovascular system. Specific structures emerge but how is synthesis regulated?

Inactivation of the gene for anticoagulant protein C causes lethal perinatal consumptive coagulopathy in mice

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

Absence of the blood-clotting regulator thrombomodulin causes embryonic lethality in mice before development of a functional cardiovascular system

Increased insulin sensitivity and hypoglycaemia in mice lacking the p85 alpha subunit of phosphoinositide 3-kinase

Molecular cloning and cell-free expression of mouse antithrombin III.

Molecular cloning and expression of two distinct cDNA-encoding heparan sulfate proteoglycan core proteins from a rat endothelial cell line.

Vascular-bed--specific hemostasis and hypercoagulable states.

Antiangiogenic activity of the cleaved conformation of the serpin antithrombin.

INHERITED ANTITHROMBIN DEFICIENCY CAUSING THROMBOPHILIA.

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873-878

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10.1172/JCI10489

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7

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106

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Kazuhiro Ishiguro

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2000-10-01T00:00:00Z

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11018075

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