The signature 3-O-sulfo group of the anticoagulant heparin sequence is critical for heparin binding to antithrombin but is not required for allosteric activation.

The signature 3-O-sulfo group of the anticoagulant heparin sequence is critical for heparin binding to antithrombin but is not required for allosteric activation.

Item
http://www.wikidata.org/entity/Q37447881
Heparan sulfate 3-O-sulfation: a rare modification in search of a function.Revisiting the association of cationic groove-binding drugs to DNA using a Poisson-Boltzmann approach.Specific sides to multifaceted glycosaminoglycans are observed in embryonic development.Exploiting enzyme specificities in digestions of chondroitin sulfates A and C: production of well-defined hexasaccharidesProbing structural selectivity of synthetic heparin binding to Stabilin protein receptorsInvestigating changes in the gas-phase conformation of Antithrombin III upon binding of Arixtra using traveling wave ion mobility spectrometry (TWIMS).Glycosaminoglycans from earthworms (Eisenia andrei).Molecular mechanisms of antithrombin-heparin regulation of blood clotting proteinases. A paradigm for understanding proteinase regulation by serpin family protein proteinase inhibitors.Insights into the role of 3-O-sulfotransferase in heparan sulfate biosynthesis.Effects of glycosylation on heparin binding and antithrombin activation by heparin.Blocking inhibition of prothrombinase by tissue factor pathway inhibitor alpha: a procoagulant property of heparins.Asparagine 405 of heparin lyase II prevents the cleavage of glycosidic linkages proximate to a 3-O-sulfoglucosamine residue.A polymer nanoparticle with engineered affinity for a vascular endothelial growth factor (VEGF165).Antithrombin stabilisation by sulfated carbohydrates correlates with anticoagulant activity
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The signature 3-O-sulfo group of the anticoagulant heparin sequence is critical for heparin binding to antithrombin but is not required for allosteric activation.

Item
http://www.wikidata.org/entity/Q37447881
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 06 August 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
The signature 3-O-sulfo group ...... red for allosteric activation.
@en
The signature 3-O-sulfo group ...... red for allosteric activation.
@nl
type
label
The signature 3-O-sulfo group ...... red for allosteric activation.
@en
The signature 3-O-sulfo group ...... red for allosteric activation.
@nl
prefLabel
The signature 3-O-sulfo group ...... red for allosteric activation.
@en
The signature 3-O-sulfo group ...... red for allosteric activation.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P698
P921
P932
P356
P1433
P1476
The signature 3-O-sulfo group ...... red for allosteric activation.
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P698
P921
P932