The Coxiella burnetii Dot/Icm system delivers a unique repertoire of type IV effectors into host cells and is required for intracellular replication.
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Bacterial Type IV secretion systems: versatile virulence machinesQuantitative image analysis and modeling indicate the Agrobacterium tumefaciens type IV secretion system is organized in a periodic pattern of fociQ28069944Contrasting Lifestyles Within the Host CellIdentification of OmpA, a Coxiella burnetii protein involved in host cell invasion, by multi-phenotypic high-content screeningStudying Coxiella burnetii Type IV Substrates in the Yeast Saccharomyces cerevisiae: Focus on Subcellular Localization and Protein AggregationGenetics of Coxiella burnetii: on the path of specializationFrom Q Fever to Coxiella burnetii Infection: a Paradigm Change.The Type IV Secretion System Effector Protein CirA Stimulates the GTPase Activity of RhoA and Is Required for Virulence in a Mouse Model of Coxiella burnetii InfectionAlterations of the Coxiella burnetii Replicative Vacuole Membrane Integrity and Interplay with the Autophagy Pathway.Essential role for the response regulator PmrA in Coxiella burnetii type 4B secretion and colonization of mammalian host cells.Coxiella burnetii type IV secretion-dependent recruitment of macrophage autophagosomes.Tracking Proteins Secreted by Bacteria: What's in the Toolbox?Physicochemical and Nutritional Requirements for Axenic Replication Suggest Physiological Basis for Coxiella burnetii Niche Restriction.Multiple Substrate Usage of Coxiella burnetii to Feed a Bipartite Metabolic Network.Molecular pathogenesis of the obligate intracellular bacterium Coxiella burnetiiIdentification of Anaplasma marginale type IV secretion system effector proteinsIdentification of novel Coxiella burnetii Icm/Dot effectors and genetic analysis of their involvement in modulating a mitogen-activated protein kinase pathway.Identification of two Legionella pneumophila effectors that manipulate host phospholipids biosynthesisThe contribution of proteomics towards deciphering the enigma of Coxiella burnetii.Effector protein translocation by the Coxiella burnetii Dot/Icm type IV secretion system requires endocytic maturation of the pathogen-occupied vacuole.Brucella modulates secretory trafficking via multiple type IV secretion effector proteins.Coxiella burnetii effector proteins that localize to the parasitophorous vacuole membrane promote intracellular replication.Sec-mediated secretion by Coxiella burnetiiDot/Icm type IVB secretion system requirements for Coxiella burnetii growth in human macrophages.A screen of Coxiella burnetii mutants reveals important roles for Dot/Icm effectors and host autophagy in vacuole biogenesisThe Coxiella burnetii Dot/Icm system creates a comfortable home through lysosomal renovation.Application of β-lactamase reporter fusions as an indicator of effector protein secretion during infections with the obligate intracellular pathogen Chlamydia trachomatisTwo systems for targeted gene deletion in Coxiella burnetiiCoxiella burnetii alters cyclic AMP-dependent protein kinase signaling during growth in macrophagesVasodilator-Stimulated Phosphoprotein Activity Is Required for Coxiella burnetii Growth in Human Macrophages.The Effector Cig57 Hijacks FCHO-Mediated Vesicular Trafficking to Facilitate Intracellular Replication of Coxiella burnetiiBiogenesis of the lysosome-derived vacuole containing Coxiella burnetii.Inhibition of inflammasome activation by Coxiella burnetii type IV secretion system effector IcaA.Host pathways important for Coxiella burnetii infection revealed by genome-wide RNA interference screening.Computational modeling and experimental validation of the Legionella and Coxiella virulence-related type-IVB secretion signal.Primary Role for Toll-Like Receptor-Driven Tumor Necrosis Factor Rather than Cytosolic Immune Detection in Restricting Coxiella burnetii Phase II Replication within Mouse MacrophagesVirulent Coxiella burnetii pathotypes productively infect primary human alveolar macrophagesDevelopment of an Ex Vivo Tissue Platform To Study the Human Lung Response to Coxiella burnetii.The inhibition of the apoptosis pathway by the Coxiella burnetii effector protein CaeA requires the EK repetition motif, but is independent of survivin
P2860
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P2860
The Coxiella burnetii Dot/Icm system delivers a unique repertoire of type IV effectors into host cells and is required for intracellular replication.
description
2011 nî lūn-bûn
@nan
2011 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
The Coxiella burnetii Dot/Icm ...... for intracellular replication.
@ast
The Coxiella burnetii Dot/Icm ...... for intracellular replication.
@en
type
label
The Coxiella burnetii Dot/Icm ...... for intracellular replication.
@ast
The Coxiella burnetii Dot/Icm ...... for intracellular replication.
@en
prefLabel
The Coxiella burnetii Dot/Icm ...... for intracellular replication.
@ast
The Coxiella burnetii Dot/Icm ...... for intracellular replication.
@en
P2093
P2860
P1433
P1476
The Coxiella burnetii Dot/Icm ...... for intracellular replication.
@en
P2093
Anja Lührmann
Craig R Roy
Hayley J Newton
Kimberly L Carey
P2860
P304
P356
10.1371/JOURNAL.PPAT.1002056
P577
2011-05-26T00:00:00Z