Human macrophages infected with a high burden of ESAT-6-expressing M. tuberculosis undergo caspase-1- and cathepsin B-independent necrosis - Wikidata - wikimedia - TriplyDB

Human macrophages infected with a high burden of ESAT-6-expressing M. tuberculosis undergo caspase-1- and cathepsin B-independent necrosis

Human macrophages infected with a high burden of ESAT-6-expressing M. tuberculosis undergo caspase-1- and cathepsin B-independent necrosis

http://www.wikidata.org/entity/Q33921372

about

Many stimuli pull the necrotic trigger, an overview Modular Organization of the ESX-5 Secretion System in Mycobacterium tuberculosis Interaction of Mycobacterium tuberculosis with host cell death pathways The innate immune response in human tuberculosis Replication rates of Mycobacterium tuberculosis in human macrophages do not correlate with mycobacterial antibiotic susceptibility Identification of a Transcription Factor That Regulates Host Cell Exit and Virulence of Mycobacterium tuberculosis Mycobacterium tuberculosis infection induces non-apoptotic cell death of human dendritic cells.Apoptotic neutrophils augment the inflammatory response to Mycobacterium tuberculosis infection in human macrophages.Detection of cytosolic bacteria by inflammatory caspases.Global gene expression and systems biology analysis of bovine monocyte-derived macrophages in response to in vitro challenge with Mycobacterium bovis Beyond macrophages: the diversity of mononuclear cells in tuberculosis.Attenuated Mycobacterium tuberculosis SO2 vaccine candidate is unable to induce cell death.Mycobacterium tuberculosis PE25/PPE41 protein complex induces necrosis in macrophages: Role in virulence and disease reactivation?Comparative functional genomics and the bovine macrophage response to strains of the mycobacterium genus.Characterizing virulence-specific perturbations in the mitochondrial function of macrophages infected with Mycobacterium tuberculosis.PE11 (Rv1169c) selectively alters fatty acid components of Mycobacterium smegmatis and host cell interleukin-6 level accompanied with cell death.Postprimary Tuberculosis and Macrophage Necrosis: Is There a Big ConNECtion?Extracellular traps and macrophages: new roles for the versatile phagocyte.Mycobacterium tuberculosis exploits human interferon γ to stimulate macrophage extracellular trap formation and necrosis.Expression of IL-1β in rhesus EAE and MS lesions is mainly induced in the CNS itself.Pathways of IL-1β secretion by macrophages infected with clinical Mycobacterium tuberculosis strains.Macrophages in tuberculosis: friend or foe.Role of Cathepsins in Mycobacterium tuberculosis Survival in Human Macrophages.Otopathogenic Pseudomonas aeruginosa Enters and Survives Inside Macrophages Phenotypic profiling of Mycobacterium tuberculosis EspA point mutants reveals that blockage of ESAT-6 and CFP-10 secretion in vitro does not always correlate with attenuation of virulence.Tryptophan biosynthesis protects mycobacteria from CD4 T-cell-mediated killing.Human gene variants linked to enhanced NLRP3 activity limit intramacrophage growth of Mycobacterium tuberculosis.Early Secreted Antigenic Target of 6-kDa of Mycobacterium tuberculosis Stimulates IL-6 Production by Macrophages through Activation of STAT3 Recognition of bacterial infection by innate immune sensors.Shortening the 'short-course' therapy- insights into host immunity may contribute to new treatment strategies for tuberculosis.The NLRP3 inflammasome: role in airway inflammation.Trained immunity: a new avenue for tuberculosis vaccine development.Mycobacterial escape from macrophage phagosomes to the cytoplasm represents an alternate adaptation mechanism.Molecular basis of mycobacterial survival in macrophages.Unravelling the networks dictating host resistance versus tolerance during pulmonary infections.NLRP3 Activation Was Regulated by DNA Methylation Modification during Mycobacterium tuberculosis Infection.Role of mitochondrial oxidative stress on lymphocyte homeostasis in patients diagnosed with extra-pulmonary tuberculosis.Mycobacterium tuberculosis PE25/PPE41 protein complex induces activation and maturation of dendritic cells and drives Th2-biased immune responses.CFP-10 from Mycobacterium tuberculosis selectively activates human neutrophils through a pertussis toxin-sensitive chemotactic receptor.Modeling Mycobacterium tuberculosis early granuloma formation in experimental human lung tissue.

P2860

Q24613714-1B1A0248-4066-4F0E-9B59-441F991ED1C9 Q26747272-AA2262F6-9D07-4BFB-9750-DADC8ADEB28D Q26852548-C5F988A2-FED2-4388-B9E5-BDEE042496D7 Q28084717-2A07C948-3371-440C-9E78-B2B3CDF51AC4 Q28544850-4E60B466-23C7-4552-A22A-DB8C7E8F3AB5 Q28552188-24A3FA93-9B50-4598-8DDB-522F8A45E38B Q31039645-372712C2-0090-4B3E-BC51-D9D5EAD22CB6 Q33855500-16FA23BC-AF30-409C-91F6-99FF2F42AEEB Q34039994-42C160DD-B485-4285-8001-220CD87402A6 Q34182182-0A3C9851-8EBF-4897-B400-DE69B8DFDBDB Q34372502-E62444A0-12F0-476C-83CF-E211A6675572 Q34428364-BD878AB2-A48C-419F-B60D-4C53436DB1DC Q34451478-F7DA25EB-FB82-47C3-A83F-39865F7434BF Q34454941-F81C905E-5B7E-4D03-BD90-2D6B57A250A1 Q34597434-D4FF6293-DBC0-420F-91DC-041A8C91FBBF Q35768918-BCF1CCDB-535F-477A-9BF7-A8974EABBB30 Q36496519-C12526C4-7D8F-4CEA-886E-445896526410 Q36607908-DD4EB2C9-DB24-4EF0-B82B-FA147365BB10 Q36882480-E6D32A32-E8D0-491B-AB0B-D985D9405E6A Q36976299-93E8C7D9-01DD-493D-8BF0-439DDBD4E7CB Q37138980-CBE5C87F-2CD4-4E64-A381-8B340F4E138D Q37147624-AE728442-384F-4FBE-A4BA-18DCEB680811 Q37215806-81499F28-4E24-4963-A4E5-C6C12688DA9B Q37421175-CD1D17C7-A9ED-4AC1-BADF-53357A508DFF Q37469773-6FCB328B-B991-4027-A4B2-6C02884F0877 Q37515820-4BCEB859-DA2C-4EB4-9DDB-31FDA85DE94F Q37582336-0B92A0E1-DC0E-4ECE-BE0F-54C555A1CCD8 Q37595300-79E9D73A-2223-42DA-A25D-D70AF00C5CE9 Q38032312-7D6B4A3E-219D-4B5F-9175-6209B1C3D722 Q38075095-796DD0ED-CBAE-4915-86AF-CE544A7DB5BE Q38151886-86589F7E-7A91-4675-80DF-FF235A7E7471 Q38646341-041FDDF5-FCF7-42C8-8CBA-43B61093DC0B Q38786048-FC9E6822-FBB2-46C2-9621-857A21420C62 Q39014492-00520E39-5222-4F3E-ACBB-A2202696854C Q39123548-609A0F0E-5850-4DB5-A185-965229A36D37 Q39639824-2A0A723C-12D9-4B76-86D0-57CA6D3B0BC5 Q40968419-17D17CEE-878C-46F7-82DD-4B52DD9496E6 Q41026903-ADDC2934-3A1C-4CD2-93FD-8F9176A4CB01 Q41693986-AAE94B2F-E3ED-4067-8962-6E7937E767D8 Q41929620-C63F877D-D1C1-47C1-B2F2-4931185858D2

P2860

Human macrophages infected with a high burden of ESAT-6-expressing M. tuberculosis undergo caspase-1- and cathepsin B-independent necrosis

http://www.wikidata.org/entity/Q33921372

description

2011 nî lūn-bûn

@nan

2011 թուականի Մայիսին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի մայիսին հրատարակված գիտական հոդված

@hy

2011年の論文

@ja

2011年論文

@yue

2011年論文

@zh-hant

2011年論文

@zh-hk

2011年論文

@zh-mo

2011年論文

@zh-tw

2011年论文

@wuu

name

Human macrophages infected wit ...... thepsin B-independent necrosis

@ast

Human macrophages infected wit ...... thepsin B-independent necrosis

@en

type

label

Human macrophages infected wit ...... thepsin B-independent necrosis

@ast

Human macrophages infected wit ...... thepsin B-independent necrosis

@en

prefLabel

Human macrophages infected wit ...... thepsin B-independent necrosis

@ast

Human macrophages infected wit ...... thepsin B-independent necrosis

@en

P1433

Q33921372-8C14DB88-A4FF-4095-91A5-4D17E07A2AF8

P1476

Q33921372-5875C067-643F-4E2F-B221-32DED177BF49

P2093

Q33921372-15A75D8C-E454-44B1-A842-75B96B37AD54

Q33921372-3B8021B0-19CC-469D-A7C3-B76F1DB98921

P2860

Q33921372-02A0067B-2632-4AAD-B5BB-4D8F7E2DEF6E

Q33921372-040EBBE7-E6F1-428E-8B28-50F2AB0E786F

Q33921372-07D8DADB-A99F-426B-987F-734172E4E496

Q33921372-08929372-D63E-4237-92BC-ED893F269A9A

Q33921372-147CBF34-5710-498D-A961-4D02F7C3E2DD

Q33921372-15FC97E9-91A3-46AD-BAE4-88C55C0B6109

Q33921372-1736A105-B47D-4A5C-AE08-106B00D891D3

Q33921372-19B9A389-C9AA-4B26-B9EC-E763E1BA3B85

Q33921372-1E3039C6-E869-48E5-9706-B152A88EBD9D

Q33921372-242F2B7A-9B60-43B0-BBB7-57DF9319E883

P304

Q33921372-8943122D-1D0E-460C-88B9-0AE258044CAA

P31

Q33921372-E9229EFB-8AA1-4C0E-81D9-8D3D19E55FB9

P356

Q33921372-69E4BF08-BFC1-43B9-84DA-D72A1789C8D7

P407

Q33921372-D1672B50-CEED-4E62-AE67-8609FD1FA487

P433

Q33921372-1C8B0173-217F-42EF-8260-17477BFA5DAD

P478

Q33921372-ABD6F836-4427-46C6-8345-F500AF76DF34

P50

Q33921372-0B60FFBE-E8F0-4A95-8A56-FAF5D76A0998

Q33921372-8EB80A28-7926-474A-8F47-0938C006FA05

P577

Q33921372-4C184891-3A96-4FB9-A5F3-E34CE3E8B6B1

P5875

Q33921372-8677CD73-7941-4EE1-AFCC-5BE7B08BC606

P698

Q33921372-E494C7CD-BE56-4B95-9B95-F6911943524A

P921

Q33921372-809C2721-EF3B-45E8-AC71-C97EAB0DD142

Q33921372-F72215FF-FC6C-42C6-AECF-77304BE60CB4

P932

Q33921372-0DD71B09-DC5C-4EE6-B505-3D5D3FB0342F

P356

JOURNAL.PONE.0020302

P1433

P1476

Human macrophages infected wit ...... thepsin B-independent necrosis

@en

P2093

Maria Lerm

http://www.w3.org/2001/XMLSchema#string

Olle Stendahl

http://www.w3.org/2001/XMLSchema#string

P2860

Neisseria gonorrhoeae activates the proteinase cathepsin B to mediate the signaling activities of the NLRP3 and ASC-containing inflammasome

Host-detrimental role of Esx-1-mediated inflammasome activation in mycobacterial infection

Release of chromatin protein HMGB1 by necrotic cells triggers inflammation

Caspase-1-dependent pore formation during pyroptosis leads to osmotic lysis of infected host macrophages

Mycobacterium tuberculosis nuoG is a virulence gene that inhibits apoptosis of infected host cells

Individual RD1-region genes are required for export of ESAT-6/CFP-10 and for virulence of Mycobacterium tuberculosis

Secreted Mycobacterium tuberculosis Rv3654c and Rv3655c proteins participate in the suppression of macrophage apoptosis

The role of the granuloma in expansion and dissemination of early tuberculous infection.

Virulent Mycobacterium tuberculosis strains evade apoptosis of infected alveolar macrophages.

A mycobacterial virulence gene cluster extending RD1 is required for cytolysis, bacterial spreading and ESAT-6 secretion.

P304

e20302

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1371/JOURNAL.PONE.0020302

http://www.w3.org/2001/XMLSchema#string

P407

P433

5

http://www.w3.org/2001/XMLSchema#string

P478

6

http://www.w3.org/2001/XMLSchema#string

P50

P577

2011-05-26T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

51188239

http://www.w3.org/2001/XMLSchema#string

P698

21637850

http://www.w3.org/2001/XMLSchema#string

P921

Akafuba bulwadde

Mycobacterium tuberculosis

P932

3102687

http://www.w3.org/2001/XMLSchema#string