Dynamic heterogeneity and DNA methylation in embryonic stem cells.
about
Epigenetic modulators, modifiers and mediators in cancer aetiology and progressionIntegration of Signaling Pathways with the Epigenetic Machinery in the Maintenance of Stem CellsImaging Transcription: Past, Present, and FutureIntra-tumor heterogeneity of cancer cells and its implications for cancer treatmentA continuum model of transcriptional bursting.Signal transduction controls heterogeneous NF-κB dynamics and target gene expression through cytokine-specific refractory states.Multiple cell and population-level interactions with mouse embryonic stem cell heterogeneity.Quantitative imaging of mammalian transcriptional dynamics: from single cells to whole embryosSingle-cell gene expression profiling and cell state dynamics: collecting data, correlating data points and connecting the dotsSurvey statistics of automated segmentations applied to optical imaging of mammalian cells.Exploiting Single-Cell Quantitative Data to Map Genetic Variants Having Probabilistic EffectsStochastic promoter activation affects Nanog expression variability in mouse embryonic stem cellsSensing relative signal in the Tgf-β/Smad pathwayTracking the embryonic stem cell transition from ground state pluripotency.Next-generation mammalian genetics toward organism-level systems biologySingle-cell ChIP-seq reveals cell subpopulations defined by chromatin state.Ancestry dependent DNA methylation and influence of maternal nutritionInferring epigenetic dynamics from kin correlations.Pluripotency, Differentiation, and Reprogramming: A Gene Expression Dynamics Model with Epigenetic Feedback Regulation.Differential variability and correlation of gene expression identifies key genes involved in neuronal differentiation.Large-scale time-lapse microscopy of Oct4 expression in human embryonic stem cell colonies.Simultaneous live imaging of the transcription and nuclear position of specific genes.Single-Cell-Based Analysis Highlights a Surge in Cell-to-Cell Molecular Variability Preceding Irreversible Commitment in a Differentiation Process.Heterogeneous pattern of DNA methylation in developmentally important genes correlates with its chromatin conformation.A survey of the approaches for identifying differential methylation using bisulfite sequencing data.Single-cell chromatin accessibility reveals principles of regulatory variationVariation is function: Are single cell differences functionally important?: Testing the hypothesis that single cell variation is required for aggregate functionChicken embryonic stem cells and primordial germ cells display different heterochromatic histone marks than their mammalian counterparts.Visualizing allele-specific expression in single cells reveals epigenetic mosaicism in an H19 loss-of-imprinting mutantSingle-cell analysis of transcription kinetics across the cell cycle.The Pluripotency Factor NANOG Binds to GLI Proteins and Represses Hedgehog-mediated Transcription.Linkage disequilibrium analysis of allelic heterogeneity in DNA methylation.Nanog, Oct4 and Tet1 interplay in establishing pluripotencyHighly variable cancer subpopulations that exhibit enhanced transcriptome variability and metastatic fitnessWhat's Luck Got to Do with It: Single Cells, Multiple Fates, and Biological Nondeterminism.Comparative Epigenomic Profiling of the DNA Methylome in Mouse and Zebrafish Uncovers High Interspecies DivergenceTradeoffs between Dense and Replicate Sampling Strategies for High-Throughput Time Series Experiments.A statistical approach for identifying differential distributions in single-cell RNA-seq experiments.A role of stochastic phenotype switching in generating mosaic endothelial cell heterogeneity.Selecting the most appropriate time points to profile in high-throughput studies.
P2860
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P2860
Dynamic heterogeneity and DNA methylation in embryonic stem cells.
description
2014 nî lūn-bûn
@nan
2014 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Dynamic heterogeneity and DNA methylation in embryonic stem cells.
@ast
Dynamic heterogeneity and DNA methylation in embryonic stem cells.
@en
type
label
Dynamic heterogeneity and DNA methylation in embryonic stem cells.
@ast
Dynamic heterogeneity and DNA methylation in embryonic stem cells.
@en
prefLabel
Dynamic heterogeneity and DNA methylation in embryonic stem cells.
@ast
Dynamic heterogeneity and DNA methylation in embryonic stem cells.
@en
P2093
P2860
P1433
P1476
Dynamic heterogeneity and DNA methylation in embryonic stem cells.
@en
P2093
Alphan Altinok
Julia Tischler
Michael B Elowitz
Zakary S Singer
P2860
P304
P356
10.1016/J.MOLCEL.2014.06.029
P577
2014-07-01T00:00:00Z