about
Germline DNA demethylation dynamics and imprint erasure through 5-hydroxymethylcytosinePrdm14 promotes germline fate and naive pluripotency by repressing FGF signalling and DNA methylationNon-genotoxic carcinogen exposure induces defined changes in the 5-hydroxymethylomeIdentification of nuclear and cytoplasmic mRNA targets for the shuttling protein SF2/ASFStella modulates transcriptional and endogenous retrovirus programs during maternal-to-zygotic transition.Activation of Lineage Regulators and Transposable Elements across a Pluripotent Spectrum.Dynamic heterogeneity and DNA methylation in embryonic stem cells.PRMT5 protects genomic integrity during global DNA demethylation in primordial germ cells and preimplantation embryos.A Unique Gene Regulatory Network Resets the Human Germline Epigenome for DevelopmentPromoter DNA methylation couples genome-defence mechanisms to epigenetic reprogramming in the mouse germline.Chromatin dynamics and the role of G9a in gene regulation and enhancer silencing during early mouse development.Synergistic mechanisms of DNA demethylation during transition to ground-state pluripotencyParallel mechanisms of epigenetic reprogramming in the germline.Regulatory principles of pluripotency: from the ground state up.The interaction of xKaiso with xTcf3: a revised model for integration of epigenetic and Wnt signalling pathways.Beyond DNA: programming and inheritance of parental methylomes.The non-methylated DNA-binding function of Kaiso is not required in early Xenopus laevis development.Tracing the Transitions from Pluripotency to Germ Cell Fate with CRISPR ScreeningTracing the transitions from pluripotency to germ cell fate with CRISPR screening
P50
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P50
description
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Jamie A Hackett
@ast
Jamie A Hackett
@en
Jamie A Hackett
@es
Jamie A Hackett
@nl
Jamie A Hackett
@sl
type
label
Jamie A Hackett
@ast
Jamie A Hackett
@en
Jamie A Hackett
@es
Jamie A Hackett
@nl
Jamie A Hackett
@sl
prefLabel
Jamie A Hackett
@ast
Jamie A Hackett
@en
Jamie A Hackett
@es
Jamie A Hackett
@nl
Jamie A Hackett
@sl
P106
P31
P496
0000-0002-6237-3684