Identification of a protein-protein interaction between KCNE1 and the activation gate machinery of KCNQ1
about
O-glycosylation of the cardiac I(Ks) complexWorking model for the structural basis for KCNE1 modulation of the KCNQ1 potassium channel.KCNE1 divides the voltage sensor movement in KCNQ1/KCNE1 channels into two stepsThe cardiac IKs channel, complex indeedKCNE1 remodels the voltage sensor of Kv7.1 to modulate channel function.Probing binding sites and mechanisms of action of an I(Ks) activator by computations and experiments.KCNE1 enhances phosphatidylinositol 4,5-bisphosphate (PIP2) sensitivity of IKs to modulate channel activity.Chemical control of metabolically-engineered voltage-gated K+ channels.Domain-domain interactions determine the gating, permeation, pharmacology, and subunit modulation of the IKs ion channelKCNQ1 subdomains involved in KCNE modulation revealed by an invertebrate KCNQ1 orthologue.Partial restoration of the long QT syndrome associated KCNQ1 A341V mutant by the KCNE1 β-subunitReconstitution of KCNE1 into lipid bilayers: comparing the structural, dynamic, and activity differences in micelle and vesicle environmentsRegulation of Voltage-Activated K(+) Channel Gating by Transmembrane β Subunits.Probing the structural basis for differential KCNQ1 modulation by KCNE1 and KCNE2KCNE1 and KCNE3: The yin and yang of voltage-gated K(+) channel regulationStructural basis for KCNE3 modulation of potassium recycling in epitheliaBuilding KCNQ1/KCNE1 channel models and probing their interactions by molecular-dynamics simulations.Gating-related molecular motions in the extracellular domain of the IKs channel: implications for IKs channelopathy.The KCNE Tango - How KCNE1 Interacts with Kv7.1.Voltage-Dependent Gating: Novel Insights from KCNQ1 Channels.KCNE1 and KCNE3 modulate KCNQ1 channels by affecting different gating transitions.
P2860
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P2860
Identification of a protein-protein interaction between KCNE1 and the activation gate machinery of KCNQ1
description
2010 nî lūn-bûn
@nan
2010 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Identification of a protein-pr ...... vation gate machinery of KCNQ1
@ast
Identification of a protein-pr ...... vation gate machinery of KCNQ1
@en
type
label
Identification of a protein-pr ...... vation gate machinery of KCNQ1
@ast
Identification of a protein-pr ...... vation gate machinery of KCNQ1
@en
prefLabel
Identification of a protein-pr ...... vation gate machinery of KCNQ1
@ast
Identification of a protein-pr ...... vation gate machinery of KCNQ1
@en
P2093
P2860
P356
P1476
Identification of a protein-pr ...... vation gate machinery of KCNQ1
@en
P2093
Anatoli Lvov
Steven D Gage
Virla M Berrios
William R Kobertz
P2860
P304
P356
10.1085/JGP.200910386
P577
2010-05-17T00:00:00Z