Polymorphic deletion of three intracellular acidic residues of the alpha 2B-adrenergic receptor decreases G protein-coupled receptor kinase-mediated phosphorylation and desensitization.
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The α2B-adrenergic receptor is mutant in cortical myoclonus and epilepsyThe insertion/deletion variation in the alpha2B-adrenoceptor does not seem to modify the risk for acute myocardial infarction, but may modify the risk for hypertension in sib-pairs from families with type 2 diabetesSignaling and regulation of G protein-coupled receptors in airway smooth muscleDown-regulation of the alpha-2C adrenergic receptor: involvement of a serine/threonine motif in the third cytoplasmic loopInterpatient variability in dexmedetomidine response: a survey of the literatureIdentification of duplicated fourth alpha2-adrenergic receptor subtype by cloning and mapping of five receptor genes in zebrafishGenetic Moderation of Stress Effects on Corticolimbic CircuitryRelationship between human evolution and neurally mediated syncope disclosed by the polymorphic sites of the adrenergic receptor gene α2B-AR.Influence of COMT val158met and ADRA2B deletion polymorphisms on recollection and familiarity components of human emotional memory.Synopsis and data synthesis of genetic association studies in hypertension for the adrenergic receptor family genes: the CUMAGAS-HYPERT database.Adrenergic receptor genotype influence on midthigh intermuscular fat response to strength training in middle-aged and older adultsDesensitization of vascular response in vivo: contribution of genetic variation in the [alpha]2B-adrenergic receptor subtype.Acute stress modulates genotype effects on amygdala processing in humans.Molecular evolution of the mammalian alpha 2B adrenergic receptor.Association between body fat response to exercise training and multilocus ADR genotypes.Impaired desensitization of a human polymorphic α2B-adrenergic receptor variant enhances its sympatho-inhibitory activity in chromaffin cells.Complex haplotypes derived from noncoding polymorphisms of the intronless alpha2A-adrenergic gene diversify receptor expression.Genetic variation in alpha2-adrenoreceptors and heart rate recovery after exercise.Alpha-adrenergic receptor gene polymorphisms and cardiovascular reactivity to stress in Black adolescents and young adults.Haplotype polymorphism in the alpha-2B-adrenergic receptor gene influences response inhibition in a large Chinese sampleAnterograde trafficking of nascent α(2B)-adrenergic receptor: structural basis, roles of small GTPasesPharmacogenomics of adrenoceptors.Spinophilin Is Indispensable for the α2B Adrenergic Receptor-Elicited Hypertensive ResponseGenetic variation in G-protein-coupled receptors--consequences for G-protein-coupled receptors as drug targets.Association of insertion/deletion polymorphism of alpha-adrenoceptor gene in essential hypertension with or without type 2 diabetes mellitus in Malaysian subjects.Lifestyle modifies the relationship between body composition and adrenergic receptor genetic polymorphisms, ADRB2, ADRB3 and ADRA2B: a secondary analysis of a randomized controlled trial of physical activity among postmenopausal women.A genetic variation of the noradrenergic system is related to differential amygdala activation during encoding of emotional memories.Common genetic variants in sudden cardiac death.Adrenergic signaling polymorphisms and their impact on cardiovascular disease.Pharmacogenomics of the heptahelical receptor regulators G-protein-coupled receptor kinases and arrestins: the known and the unknown.80K-H as a new Ca2+ sensor regulating the activity of the epithelial Ca2+ channel transient receptor potential cation channel V5 (TRPV5).Ubiquitination and the Regulation of Membrane Proteins.Chronic adrenaline treatment fails to down-regulate the Del301-303-alpha2B-adrenoceptor in neuronal cells.Agonist-induced formation of opioid receptor-G protein-coupled receptor kinase (GRK)-G beta gamma complex on membrane is required for GRK2 function in vivo.Genesis and Maintenance of Attentional Biases: The Role of the Locus Coeruleus-Noradrenaline System.The Gordon Wilson Lecture: neurohormonal signaling pathways that link cardiac growth and death.ADRA2B genotype differentially modulates stress-induced neural activity in the amygdala and hippocampus during emotional memory retrieval.Impact of the CYP2D6 genotype on the clinical effects of metoprolol: a prospective longitudinal study.Blood pressure and metabolic phenotypes in relation to the ADRB1 Arg389Gly and ADRA2B I/D polymorphisms in a White population.Intracellularly truncated human alpha2B-adrenoceptors: stable and functional GPCRs for structural studies.
P2860
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P2860
Polymorphic deletion of three intracellular acidic residues of the alpha 2B-adrenergic receptor decreases G protein-coupled receptor kinase-mediated phosphorylation and desensitization.
description
2000 nî lūn-bûn
@nan
2000 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Polymorphic deletion of three ...... orylation and desensitization.
@ast
Polymorphic deletion of three ...... orylation and desensitization.
@en
type
label
Polymorphic deletion of three ...... orylation and desensitization.
@ast
Polymorphic deletion of three ...... orylation and desensitization.
@en
prefLabel
Polymorphic deletion of three ...... orylation and desensitization.
@ast
Polymorphic deletion of three ...... orylation and desensitization.
@en
P2093
P2860
P356
P1476
Polymorphic deletion of three ...... orylation and desensitization.
@en
P2093
P2860
P304
P356
10.1074/JBC.M008118200
P407
P577
2000-10-30T00:00:00Z