Complex haplotypes derived from noncoding polymorphisms of the intronless alpha2A-adrenergic gene diversify receptor expression. - Wikidata - wikimedia - TriplyDB

Complex haplotypes derived from noncoding polymorphisms of the intronless alpha2A-adrenergic gene diversify receptor expression.

Complex haplotypes derived from noncoding polymorphisms of the intronless alpha2A-adrenergic gene diversify receptor expression.

http://www.wikidata.org/entity/Q34600291

about

Overexpression of alpha2A-adrenergic receptors contributes to type 2 diabetes Polymorphisms in human heat shock factor-1 and analysis of potential biological consequences.Genome-wide meta-analyses identifies seven loci associated with platelet aggregation in response to agonists.Genetic variations in the α(2A)-adrenoreceptor are associated with blood pressure response to the agonist dexmedetomidine Variants of ADRA2A are associated with fasting glucose, blood pressure, body mass index and type 2 diabetes risk: meta-analysis of four prospective studies.The genetics of common variation affecting platelet development, function and pharmaceutical targeting.Genetic variation in alpha2-adrenoreceptors and heart rate recovery after exercise.ADRA2A is involved in neuro-endocrine regulation of bone resorption.Mechanisms of pharmacogenomic effects of genetic variation within the cardiac adrenergic network in heart failure alpha2A-adrenergic receptors in the genetics, pathogenesis, and treatment of type 2 diabetes.Adrenergic signaling polymorphisms and their impact on cardiovascular disease.α2-adrenoceptor regulation of blood glucose homeostasis.Advances in our understanding of the molecular basis of disorders of platelet function.Genetic variant rs3750625 in the 3'UTR of ADRA2A affects stress-dependent acute pain severity after trauma and alters a microRNA-34a regulatory site.Common α2A and α2C adrenergic receptor polymorphisms do not affect plasma membrane trafficking.Variable-length poly-C tract polymorphisms of the beta2-adrenergic receptor 3'-UTR alter expression and agonist regulation.ADRA2A Germline Gene Polymorphism is Associated to the Severity, but not to the Risk, of Breast Cancer.Diversity and impact of rare variants in genes encoding the platelet G protein-coupled receptors.Impaired responsiveness of platelets to epinephrine due to α2A adrenoreceptor deficiency in Male Chinese.

P2860

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P2860

Complex haplotypes derived from noncoding polymorphisms of the intronless alpha2A-adrenergic gene diversify receptor expression.

http://www.wikidata.org/entity/Q34600291

description

2006 nî lūn-bûn

@nan

2006 թուականի Մարտին հրատարակուած գիտական յօդուած

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2006 թվականի մարտին հրատարակված գիտական հոդված

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2006年の論文

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2006年学术文章

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2006年学术文章

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2006年学术文章

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2006年学术文章

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2006年学术文章

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2006年學術文章

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name

Complex haplotypes derived fro ...... diversify receptor expression.

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Complex haplotypes derived fro ...... diversify receptor expression.

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Complex haplotypes derived fro ...... diversify receptor expression.

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type

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Complex haplotypes derived fro ...... diversify receptor expression.

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Complex haplotypes derived fro ...... diversify receptor expression.

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Complex haplotypes derived fro ...... diversify receptor expression.

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prefLabel

Complex haplotypes derived fro ...... diversify receptor expression.

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Complex haplotypes derived fro ...... diversify receptor expression.

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Complex haplotypes derived fro ...... diversify receptor expression.

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PNAS.0601345103

P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

Complex haplotypes derived fro ...... diversify receptor expression.

@en

P2093

Carrie A Seman

http://www.w3.org/2001/XMLSchema#string

Cheryl T Theiss

http://www.w3.org/2001/XMLSchema#string

Kari M Brown

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Kersten M Small

http://www.w3.org/2001/XMLSchema#string

Stephen B Liggett

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P2860

A gain-of-function polymorphism in a G-protein coupling domain of the human beta1-adrenergic receptor

An asn to lys polymorphism in the third intracellular loop of the human alpha 2A-adrenergic receptor imparts enhanced agonist-promoted Gi coupling

Polymorphisms of cardiac presynaptic alpha2C adrenergic receptors: Diverse intragenic variability with haplotype-specific functional effects

A New Statistical Method for Haplotype Reconstruction from Population Data

A simple method for estimating evolutionary rates of base substitutions through comparative studies of nucleotide sequences

Pharmacogenetics of antihypertensive drug responses

Genetic determinants of blood pressure regulation.

Two functionally distinct alpha2-adrenergic receptors regulate sympathetic neurotransmission.

A four amino acid deletion polymorphism in the third intracellular loop of the human alpha 2C-adrenergic receptor confers impaired coupling to multiple effectors.

Polymorphic deletion of three intracellular acidic residues of the alpha 2B-adrenergic receptor decreases G protein-coupled receptor kinase-mediated phosphorylation and desensitization.

P304

5472-5477

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scholarly article

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10.1073/PNAS.0601345103

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14

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103

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7210923

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16567612

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1459379

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