An atomic resolution view of ICAM recognition in a complex between the binding domains of ICAM-3 and integrin alphaLbeta2.
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An Unusual Allosteric Mobility of the C-Terminal Helix of a High-Affinity αL Integrin I Domain Variant Bound to ICAM-5Structure of the F-spondin domain of mindin, an integrin ligand and pattern recognition moleculeThe crystal structure of the signature domain of cartilage oligomeric matrix protein: implications for collagen, glycosaminoglycan and integrin bindingStructural basis of activation-dependent binding of ligand-mimetic antibody AL-57 to integrin LFA-1Stable Coordination of the Inhibitory Ca2+ Ion at the Metal Ion-Dependent Adhesion Site in Integrin CD11b/CD18 by an Antibody-Derived Ligand Aspartate: Implications for Integrin Regulation and Structure-Based Drug DesignCrystal structures of an ICAM-5 ectodomain fragment show electrostatic-based homophilic adhesionsThe Crystal Structure of the Ubiquitin-like Domain of Ribosome Assembly Factor Ytm1 and Characterization of Its Interaction with the AAA-ATPase MidasinRational design of intercellular adhesion molecule-1 (ICAM-1) variants for antagonizing integrin lymphocyte function-associated antigen-1-dependent adhesionStructural basis of integrin regulation and signalingA small molecule agonist of an integrin, alphaLbeta2.Complex structure of engineered modular domains defining molecular interaction between ICAM-1 and integrin LFA-1Differential role of ICAM ligands in determination of human memory T cell differentiationEngineering of single Ig superfamily domain of intercellular adhesion molecule 1 (ICAM-1) for native fold and function.Conformational stability analyses of alpha subunit I domain of LFA-1 and Mac-1Why integrin as a primary target for imaging and therapy.AL-57, a ligand-mimetic antibody to integrin LFA-1, reveals chemokine-induced affinity up-regulation in lymphocytes.Crystal structure of the Rad3/XPD regulatory domain of Ssl1/p44.Early chordate origin of the vertebrate integrin αI domains.Molecular basis for complement recognition by integrin αXβ2.The regulation of integrin function by divalent cations.The connection between metal ion affinity and ligand affinity in integrin I domainsDynamic structural changes are observed upon collagen and metal ion binding to the integrin α1 I domain.Isoflurane binds and stabilizes a closed conformation of the leukocyte function-associated antigen-1.Domain 1 of mucosal addressin cell adhesion molecule has an I1-set fold and a flexible integrin-binding loopLeukocyte integrin αLβ2 headpiece structures: The αI domain, the pocket for the internal ligand, and concerted movements of its loops.Structural modifications of ICAM-1 cyclic peptides to improve the activity to inhibit heterotypic adhesion of T cellsForce spectroscopy of LFA-1 and its ligands, ICAM-1 and ICAM-2.Structural basis of Dscam1 homodimerization: Insights into context constraint for protein recognitionThe interaction of Thrombospondins with extracellular matrix proteins.Rolling cell adhesionThe leucocyte β2 (CD18) integrins: the structure, functional regulation and signalling properties.The cytosolic protein talin induces an intermediate affinity integrin alphaLbeta2.Epitope mapping of monoclonal antibody to integrin alphaL beta2 hybrid domain suggests different requirements of affinity states for intercellular adhesion molecules (ICAM)-1 and ICAM-3 binding.2E8 binds to the high affinity I-domain in a metal ion-dependent manner: a second generation monoclonal antibody selectively targeting activated LFA-1.Sequence composition predicts immunoglobulin superfamily members that could share the intrinsically disordered properties of antibody CH1 domainsSalt bridge interactions within the β2 integrin α7 helix mediate force-induced binding and shear resistance ability.Forced-rupture of cell-adhesion complexes reveals abrupt switch between two brittle states.Ligand- and cation-induced structural alterations of the leukocyte integrin LFA-1.
P2860
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P2860
An atomic resolution view of ICAM recognition in a complex between the binding domains of ICAM-3 and integrin alphaLbeta2.
description
2005 nî lūn-bûn
@nan
2005 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
An atomic resolution view of I ...... AM-3 and integrin alphaLbeta2.
@ast
An atomic resolution view of I ...... AM-3 and integrin alphaLbeta2.
@en
type
label
An atomic resolution view of I ...... AM-3 and integrin alphaLbeta2.
@ast
An atomic resolution view of I ...... AM-3 and integrin alphaLbeta2.
@en
prefLabel
An atomic resolution view of I ...... AM-3 and integrin alphaLbeta2.
@ast
An atomic resolution view of I ...... AM-3 and integrin alphaLbeta2.
@en
P2093
P2860
P356
P1476
An atomic resolution view of I ...... AM-3 and integrin alphaLbeta2.
@en
P2093
Jia-Huai Wang
Jin-Huan Liu
Jose M Casasnovas
Motomu Shimaoka
Timothy A Springer
Yuting Yang
P2860
P304
P356
10.1073/PNAS.0500200102
P407
P577
2005-02-22T00:00:00Z