Epitope mapping of monoclonal antibody to integrin alphaL beta2 hybrid domain suggests different requirements of affinity states for intercellular adhesion molecules (ICAM)-1 and ICAM-3 binding.
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Disruption of the integrin alphaLbeta2 transmembrane domain interface by beta2 Thr-686 mutation activates alphaLbeta2 and promotes micro-clustering of the alphaL subunitsA structural hypothesis for the transition between bent and extended conformations of the leukocyte beta2 integrinsStructure of an integrin with an αI domain, complement receptor type 4Structural basis of integrin regulation and signalingSignal-dependent slow leukocyte rolling does not require cytoskeletal anchorage of P-selectin glycoprotein ligand-1 (PSGL-1) or integrin αLβ2.Requirement of open headpiece conformation for activation of leukocyte integrin alphaXbeta2.Modulation of integrin activation by an entropic spring in the {beta}-kneeRegulation of integrin affinity on cell surfacesTests of the extension and deadbolt models of integrin activationMulti-Inhibitory Effects of A2A Adenosine Receptor Signaling on Neutrophil Adhesion Under FlowIsoflurane binds and stabilizes a closed conformation of the leukocyte function-associated antigen-1.Integrin structures and conformational signalingMutation of a conserved asparagine in the I-like domain promotes constitutively active integrins alphaLbeta2 and alphaIIbbeta3.The leucocyte β2 (CD18) integrins: the structure, functional regulation and signalling properties.The cytosolic protein talin induces an intermediate affinity integrin alphaLbeta2.A novel multi-parameter assay to dissect the pharmacological effects of different modes of integrin αLβ2 inhibition in whole blood.The effect of rhG-CSF on the conformation of LFA-1 on CD4+ T cells in hemopoietic stem cell transplantation.Urokinase-type plasminogen activator receptor induces conformational changes in the integrin alphaMbeta2 headpiece and reorientation of its transmembrane domains.Two functional active conformations of the integrin {alpha}2{beta}1, depending on activation condition and cell type.Hypoxia Enhances Fusion of Oral Squamous Carcinoma Cells and Epithelial Cells Partly via the Epithelial-Mesenchymal Transition of Epithelial Cells.Co-culture of hematopoietic stem cells with mesenchymal stem cells increases VCAM-1-dependent migration of primitive hematopoietic stem cells.Activated integrins identify functional antigen-specific CD8+ T cells within minutes after antigen stimulation.
P2860
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P2860
Epitope mapping of monoclonal antibody to integrin alphaL beta2 hybrid domain suggests different requirements of affinity states for intercellular adhesion molecules (ICAM)-1 and ICAM-3 binding.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
Epitope mapping of monoclonal ...... s (ICAM)-1 and ICAM-3 binding.
@en
type
label
Epitope mapping of monoclonal ...... s (ICAM)-1 and ICAM-3 binding.
@en
prefLabel
Epitope mapping of monoclonal ...... s (ICAM)-1 and ICAM-3 binding.
@en
P2093
P2860
P356
P1476
Epitope mapping of monoclonal ...... s (ICAM)-1 and ICAM-3 binding.
@en
P2093
Emilia Tng
Ren-Hong Tang
S K Alex Law
Suet-Mien Tan
P2860
P304
29208-29216
P356
10.1074/JBC.M503239200
P407
P577
2005-06-15T00:00:00Z